SYCP2_ARATH
ID SYCP2_ARATH Reviewed; 856 AA.
AC P61430; Q4TWG1; Q9LME3;
DT 24-MAY-2004, integrated into UniProtKB/Swiss-Prot.
DT 24-MAY-2004, sequence version 1.
DT 25-MAY-2022, entry version 96.
DE RecName: Full=Synaptonemal complex protein 2;
DE AltName: Full=Synaptonemal complex central region protein ZYP1b;
GN Name=ZYP1B; OrderedLocusNames=At1g22275; ORFNames=T16E15.14;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=16230536; DOI=10.1101/gad.354705;
RA Higgins J.D., Sanchez-Moran E., Armstrong S.J., Jones G.H., Franklin F.C.;
RT "The Arabidopsis synaptonemal complex protein ZYP1 is required for
RT chromosome synapsis and normal fidelity of crossing over.";
RL Genes Dev. 19:2488-2500(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
CC -!- FUNCTION: Required for chromosome synapsis and normal fidelity of
CC crossing over.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF87264.1; Type=Erroneous gene model prediction; Note=The predicted gene At1g22270 has been split into 2 genes: At1g22270 and At1g22275.; Evidence={ECO:0000305};
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DR EMBL; DQ028765; AAY46120.1; -; mRNA.
DR EMBL; AC068562; AAF87264.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002684; AEE30219.1; -; Genomic_DNA.
DR PIR; E86355; E86355.
DR RefSeq; NP_564164.1; NM_102078.3.
DR AlphaFoldDB; P61430; -.
DR SMR; P61430; -.
DR BioGRID; 24073; 1.
DR STRING; 3702.AT1G22275.1; -.
DR PaxDb; P61430; -.
DR PRIDE; P61430; -.
DR EnsemblPlants; AT1G22275.1; AT1G22275.1; AT1G22275.
DR GeneID; 838834; -.
DR Gramene; AT1G22275.1; AT1G22275.1; AT1G22275.
DR KEGG; ath:AT1G22275; -.
DR Araport; AT1G22275; -.
DR TAIR; locus:505006139; AT1G22275.
DR eggNOG; ENOG502QSSX; Eukaryota.
DR HOGENOM; CLU_010415_0_0_1; -.
DR InParanoid; P61430; -.
DR OrthoDB; 251210at2759; -.
DR PhylomeDB; P61430; -.
DR PRO; PR:P61430; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; P61430; baseline and differential.
DR Genevisible; P61430; AT.
DR GO; GO:0005634; C:nucleus; HDA:TAIR.
DR GO; GO:0000795; C:synaptonemal complex; IDA:TAIR.
DR GO; GO:0051301; P:cell division; IEA:UniProtKB-KW.
DR GO; GO:0007129; P:homologous chromosome pairing at meiosis; IMP:TAIR.
DR GO; GO:0007131; P:reciprocal meiotic recombination; IMP:TAIR.
PE 2: Evidence at transcript level;
KW Cell cycle; Cell division; Coiled coil; Meiosis; Nucleus;
KW Reference proteome.
FT CHAIN 1..856
FT /note="Synaptonemal complex protein 2"
FT /id="PRO_0000220591"
FT REGION 711..743
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 826..856
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 78..193
FT /evidence="ECO:0000255"
FT COILED 332..598
FT /evidence="ECO:0000255"
FT COILED 635..705
FT /evidence="ECO:0000255"
FT COMPBIAS 717..743
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 856 AA; 99022 MW; A1763DA73833144F CRC64;
MQKLGFPAMK SFDQLRSLPG SAKTYFFSTR PPQDSVSSGS FSNLKLTAEK LVKDQAAMRT
DLELANCKLK KSMEHVYALE EKLQSAFNEN AKLRVRQKED EKLWRGLESK FSSTKTLCDQ
LTETLQHLAS QVQDAEKDKG FFETKFNTSS EAINSLNQQM RDMSLRLDAA KEEITSRDKE
LEELKLEKQH KEMFYQTERC GTASLIEKKD AVITELETTA AERKLKIEKL NSQLEKLHLE
LTTKEDEVIH LVSIQEKLEK EKTNVQLSSD ELFEKLVRSE QEVKKLDELV HYLIAELTEL
DKKNLTFKEK FDKLSGLYDT HFMLLRKDRD LASDRAQRSF DQLQGELFRV AAEKEALESS
GNELSEKIVE LQNDKESLIS QLSGVRCSAS QTIDKLEFEA KGLVLKNAET ESVISKLKEE
IDTLLESVRT SEDKKKELSI KLSSLEIESK DKYEKLQADA QRQVGELETL QKESESHQLQ
ADLLAKEVNQ LQTIIEEKGH LILQCNENEK NINQQIIKDK ELLATAETKL AEAKKQYDLM
LESKQLELSR HLKELSQRND QAINEIRRKY DVEKHEIINS EKDKVEKIIK ELSTKYDKGL
SDCKEESKRQ LLTIQEEHSS RILNIREEHE SKELNLKAKY DQELRQNQIQ AENELKERIT
ALKSEHDAQL KAFKCQYEDD CKKLQEELDL QRKKEERQRA LVQLQWKVMS DNPPEEQEVN
SNKDYSHSSV KVKESRLGGN KRSEHITESP FVKAKVTSVS NILKEATNPK HHSKVTHREY
EVETNNGRIP KRRKTRQTTM FQEPQRRSTR LTPKLMTPTI IAKETAMADH PHSANIGDLF
SEGSLNPYAD DPYAFD
