ID   BIOR_THESB              Reviewed;          25 AA.
AC   P86277;
DT   19-JAN-2010, integrated into UniProtKB/Swiss-Prot.
DT   19-JAN-2010, sequence version 1.
DT   25-MAY-2022, entry version 25.
DE   RecName: Full=Bioremediase {ECO:0000303|Ref.1};
DE   Flags: Fragment;
OS   Thermoanaerobacter sp.
OC   Bacteria; Firmicutes; Clostridia; Thermoanaerobacterales;
OC   Thermoanaerobacteraceae; Thermoanaerobacter;
OC   unclassified Thermoanaerobacter.
OX   NCBI_TaxID=1755;
RN   [1]
RP   PROTEIN SEQUENCE, FUNCTION, AND BIOTECHNOLOGY.
RC   STRAIN=BKH1 {ECO:0000269|Ref.1};
RX   DOI=10.1016/j.enzm ictec.2010.03.005;
RA   Biswas S., Majumdar S., Chowdhury T., Chattopadhyay B., Mandal S.,
RA   Halder U.C., Yamasaki S.;
RT   "Bioremediase a unique protein from a novel bacterium BKH1, ushering a new
RT   hope in concrete technology.";
RL   Enzyme Microb. Technol. 46:581-587(2010).
RN   [2]
RP   FUNCTION, COFACTOR, IDENTIFICATION BY MASS SPECTROMETRY, AND BIOTECHNOLOGY.
RC   STRAIN=BKH1;
RX   PubMed=25944503; DOI=10.1007/s00775-015-1266-2;
RA   Chowdhury T., Sarkar M., Chaudhuri B., Chattopadhyay B., Halder U.C.;
RT   "Participatory role of zinc in structural and functional characterization
RT   of bioremediase: a unique thermostable microbial silica leaching protein.";
RL   J. Biol. Inorg. Chem. 20:791-803(2015).
CC   -!- FUNCTION: Releases silica from silica-rich substances.
CC       {ECO:0000269|PubMed:25944503, ECO:0000269|Ref.1}.
CC   -!- COFACTOR:
CC       Name=Zn(2+); Xref=ChEBI:CHEBI:29105;
CC         Evidence={ECO:0000269|PubMed:25944503};
CC   -!- BIOTECHNOLOGY: Has a potential use in the concrete technology for the
CC       development of an inherent and more durable concrete material.
CC       {ECO:0000269|PubMed:25944503, ECO:0000269|Ref.1}.
CC   -!- SIMILARITY: Belongs to the alpha-carbonic anhydrase family.
CC       {ECO:0000305}.
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DR   AlphaFoldDB; P86277; -.
DR   SMR; P86277; -.
DR   InterPro; IPR001148; CA_dom.
DR   Pfam; PF00194; Carb_anhydrase; 1.
DR   PROSITE; PS51144; ALPHA_CA_2; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing.
FT   CHAIN           1..>25
FT                   /note="Bioremediase"
FT                   /id="PRO_0000390702"
FT   DOMAIN          1..>25
FT                   /note="Alpha-carbonic anhydrase"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01134"
FT   REGION          1..25
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   NON_TER         25
FT                   /evidence="ECO:0000303|Ref.1"
SQ   SEQUENCE   25 AA;  2683 MW;  062899DF2FC75CA1 CRC64;
     DFPIANGERQ SPVDIDTKAV VQDPA