ID   BIOS_RHIME              Reviewed;         217 AA.
AC   O08250;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   02-NOV-2001, sequence version 2.
DT   25-MAY-2022, entry version 90.
DE   RecName: Full=Biotin transport regulator;
GN   Name=bioS; OrderedLocusNames=R01535; ORFNames=SMc02061;
OS   Rhizobium meliloti (strain 1021) (Ensifer meliloti) (Sinorhizobium
OS   meliloti).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Sinorhizobium/Ensifer group; Sinorhizobium.
OX   NCBI_TaxID=266834;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=1021;
RX   PubMed=9304864; DOI=10.1094/mpmi.1997.10.7.933;
RA   Streit W.R., Phillips D.A.;
RT   "A biotin-regulated locus, bioS, in a possible survival operon of Rhizobium
RT   meliloti.";
RL   Mol. Plant Microbe Interact. 10:933-937(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1021;
RX   PubMed=11481430; DOI=10.1073/pnas.161294398;
RA   Capela D., Barloy-Hubler F., Gouzy J., Bothe G., Ampe F., Batut J.,
RA   Boistard P., Becker A., Boutry M., Cadieu E., Dreano S., Gloux S.,
RA   Godrie T., Goffeau A., Kahn D., Kiss E., Lelaure V., Masuy D., Pohl T.,
RA   Portetelle D., Puehler A., Purnelle B., Ramsperger U., Renard C.,
RA   Thebault P., Vandenbol M., Weidner S., Galibert F.;
RT   "Analysis of the chromosome sequence of the legume symbiont Sinorhizobium
RT   meliloti strain 1021.";
RL   Proc. Natl. Acad. Sci. U.S.A. 98:9877-9882(2001).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1021;
RX   PubMed=11474104; DOI=10.1126/science.1060966;
RA   Galibert F., Finan T.M., Long S.R., Puehler A., Abola P., Ampe F.,
RA   Barloy-Hubler F., Barnett M.J., Becker A., Boistard P., Bothe G.,
RA   Boutry M., Bowser L., Buhrmester J., Cadieu E., Capela D., Chain P.,
RA   Cowie A., Davis R.W., Dreano S., Federspiel N.A., Fisher R.F., Gloux S.,
RA   Godrie T., Goffeau A., Golding B., Gouzy J., Gurjal M., Hernandez-Lucas I.,
RA   Hong A., Huizar L., Hyman R.W., Jones T., Kahn D., Kahn M.L., Kalman S.,
RA   Keating D.H., Kiss E., Komp C., Lelaure V., Masuy D., Palm C., Peck M.C.,
RA   Pohl T.M., Portetelle D., Purnelle B., Ramsperger U., Surzycki R.,
RA   Thebault P., Vandenbol M., Vorhoelter F.J., Weidner S., Wells D.H.,
RA   Wong K., Yeh K.-C., Batut J.;
RT   "The composite genome of the legume symbiont Sinorhizobium meliloti.";
RL   Science 293:668-672(2001).
RN   [4]
RP   CHARACTERIZATION.
RX   PubMed=10494632; DOI=10.1094/mpmi.1999.12.9.803;
RA   Heinz E.B., Phillips D.A., Streit W.R.;
RT   "BioS, a biotin-induced, stationary-phase, and possible LysR-type regulator
RT   in Sinorhizobium meliloti.";
RL   Mol. Plant Microbe Interact. 12:803-812(1999).
CC   -!- FUNCTION: May be part of a system that R.meliloti uses to respond to
CC       plant (alfalfa) biotin signals.
CC   -!- CAUTION: When this protein is expressed in E.coli it migrates as a 36
CC       kDa protein; thus the sequence may be incorrect in the C-terminal
CC       section. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAB88076.1; Type=Frameshift; Evidence={ECO:0000305};
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DR   EMBL; U81296; AAB88076.1; ALT_FRAME; Genomic_DNA.
DR   EMBL; AL591688; CAC46114.1; -; Genomic_DNA.
DR   RefSeq; NP_385641.1; NC_003047.1.
DR   RefSeq; WP_010969285.1; NC_003047.1.
DR   AlphaFoldDB; O08250; -.
DR   STRING; 266834.SMc02061; -.
DR   EnsemblBacteria; CAC46114; CAC46114; SMc02061.
DR   GeneID; 61602998; -.
DR   KEGG; sme:SMc02061; -.
DR   PATRIC; fig|266834.11.peg.2958; -.
DR   eggNOG; ENOG5031B54; Bacteria.
DR   HOGENOM; CLU_1276756_0_0_5; -.
DR   OMA; FVGWDVG; -.
DR   Proteomes; UP000001976; Chromosome.
PE   1: Evidence at protein level;
KW   Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..217
FT                   /note="Biotin transport regulator"
FT                   /id="PRO_0000064929"
FT   REGION          14..49
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   217 AA;  23827 MW;  AEA5E029C076DD80 CRC64;
     MQIENRLNAA AASGDGLGNL AGRSADPTGA ADKGESGVPV PPTGFVDPTP RISLSADALL
     YLGRAKRTPE KLPPLTKDEW NNRLSPQLAA REHQAFGRLA ETGDYRAYYR AFIDYYDGLR
     PEDQNSLRYF GTREAAVAGL RSLDYDADSG LDMDAEFENL VSVFLEEDKI APSPATTTMS
     PAERAFFAWD ASNISYEVDA PEPRPMTEIE RLYSELL