ID   SYDP_ECOBW              Reviewed;         181 AA.
AC   C4ZZU8;
DT   22-SEP-2009, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 1.
DT   25-MAY-2022, entry version 57.
DE   RecName: Full=Protein Syd {ECO:0000255|HAMAP-Rule:MF_01104};
GN   Name=syd {ECO:0000255|HAMAP-Rule:MF_01104}; OrderedLocusNames=BWG_2531;
OS   Escherichia coli (strain K12 / MC4100 / BW2952).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=595496;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MC4100 / BW2952;
RX   PubMed=19376874; DOI=10.1128/jb.00118-09;
RA   Ferenci T., Zhou Z., Betteridge T., Ren Y., Liu Y., Feng L., Reeves P.R.,
RA   Wang L.;
RT   "Genomic sequencing reveals regulatory mutations and recombinational events
RT   in the widely used MC4100 lineage of Escherichia coli K-12.";
RL   J. Bacteriol. 191:4025-4029(2009).
CC   -!- FUNCTION: Interacts with the SecY protein in vivo. May bind
CC       preferentially to an uncomplexed state of SecY, thus functioning either
CC       as a chelating agent for excess SecY in the cell or as a regulatory
CC       factor that negatively controls the translocase function.
CC       {ECO:0000255|HAMAP-Rule:MF_01104}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01104}; Peripheral membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01104}; Cytoplasmic side {ECO:0000255|HAMAP-Rule:MF_01104}.
CC       Note=Loosely associated with the cytoplasmic side of the inner
CC       membrane, probably via SecY. {ECO:0000255|HAMAP-Rule:MF_01104}.
CC   -!- SIMILARITY: Belongs to the Syd family. {ECO:0000255|HAMAP-
CC       Rule:MF_01104}.
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DR   EMBL; CP001396; ACR64912.1; -; Genomic_DNA.
DR   RefSeq; WP_000342431.1; NC_012759.1.
DR   AlphaFoldDB; C4ZZU8; -.
DR   SMR; C4ZZU8; -.
DR   GeneID; 58390453; -.
DR   KEGG; ebw:BWG_2531; -.
DR   HOGENOM; CLU_121866_0_0_6; -.
DR   OMA; GIPSPCI; -.
DR   GO; GO:0009898; C:cytoplasmic side of plasma membrane; IEA:InterPro.
DR   CDD; cd16323; Syd; 1.
DR   Gene3D; 3.40.1580.20; -; 1.
DR   HAMAP; MF_01104; Syd; 1.
DR   InterPro; IPR009948; Syd.
DR   InterPro; IPR038228; Syd_sf.
DR   Pfam; PF07348; Syd; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane.
FT   CHAIN           1..181
FT                   /note="Protein Syd"
FT                   /id="PRO_1000213553"
SQ   SEQUENCE   181 AA;  20708 MW;  95F6490B168DC222 CRC64;
     MDDLTAQALK DFTARYCDAW HEEHKSWPLS EELYGVPSPC IISTTEDAVY WQPQPFTGEQ
     NVNAVERAFD IVIQPTIHTF YTTQFAGDMH AQFGDIKLTL LQTWSEDDFR RVQENLIGHL
     VTQKRLKLPP TLFIATLEEE LEVISVCNLS GEVCKETLGT RKRTHLASNL AEFLNQLKPL
     L