ID   SYDP_ECODH              Reviewed;         181 AA.
AC   B1XDK2;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   20-MAY-2008, sequence version 1.
DT   03-AUG-2022, entry version 68.
DE   RecName: Full=Protein Syd {ECO:0000255|HAMAP-Rule:MF_01104};
GN   Name=syd {ECO:0000255|HAMAP-Rule:MF_01104}; OrderedLocusNames=ECDH10B_2962;
OS   Escherichia coli (strain K12 / DH10B).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=316385;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / DH10B;
RX   PubMed=18245285; DOI=10.1128/jb.01695-07;
RA   Durfee T., Nelson R., Baldwin S., Plunkett G. III, Burland V., Mau B.,
RA   Petrosino J.F., Qin X., Muzny D.M., Ayele M., Gibbs R.A., Csorgo B.,
RA   Posfai G., Weinstock G.M., Blattner F.R.;
RT   "The complete genome sequence of Escherichia coli DH10B: insights into the
RT   biology of a laboratory workhorse.";
RL   J. Bacteriol. 190:2597-2606(2008).
CC   -!- FUNCTION: Interacts with the SecY protein in vivo. May bind
CC       preferentially to an uncomplexed state of SecY, thus functioning either
CC       as a chelating agent for excess SecY in the cell or as a regulatory
CC       factor that negatively controls the translocase function.
CC       {ECO:0000255|HAMAP-Rule:MF_01104}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_01104}; Peripheral membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_01104}; Cytoplasmic side {ECO:0000255|HAMAP-Rule:MF_01104}.
CC       Note=Loosely associated with the cytoplasmic side of the inner
CC       membrane, probably via SecY. {ECO:0000255|HAMAP-Rule:MF_01104}.
CC   -!- SIMILARITY: Belongs to the Syd family. {ECO:0000255|HAMAP-
CC       Rule:MF_01104}.
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DR   EMBL; CP000948; ACB03906.1; -; Genomic_DNA.
DR   RefSeq; WP_000342431.1; NC_010473.1.
DR   AlphaFoldDB; B1XDK2; -.
DR   SMR; B1XDK2; -.
DR   GeneID; 58390453; -.
DR   KEGG; ecd:ECDH10B_2962; -.
DR   HOGENOM; CLU_121866_0_0_6; -.
DR   OMA; GIPSPCI; -.
DR   BioCyc; ECOL316385:ECDH10B_RS15055-MON; -.
DR   GO; GO:0009898; C:cytoplasmic side of plasma membrane; IEA:InterPro.
DR   CDD; cd16323; Syd; 1.
DR   Gene3D; 3.40.1580.20; -; 1.
DR   HAMAP; MF_01104; Syd; 1.
DR   InterPro; IPR009948; Syd.
DR   InterPro; IPR038228; Syd_sf.
DR   Pfam; PF07348; Syd; 1.
PE   3: Inferred from homology;
KW   Cell inner membrane; Cell membrane; Membrane.
FT   CHAIN           1..181
FT                   /note="Protein Syd"
FT                   /id="PRO_1000137028"
SQ   SEQUENCE   181 AA;  20708 MW;  95F6490B168DC222 CRC64;
     MDDLTAQALK DFTARYCDAW HEEHKSWPLS EELYGVPSPC IISTTEDAVY WQPQPFTGEQ
     NVNAVERAFD IVIQPTIHTF YTTQFAGDMH AQFGDIKLTL LQTWSEDDFR RVQENLIGHL
     VTQKRLKLPP TLFIATLEEE LEVISVCNLS GEVCKETLGT RKRTHLASNL AEFLNQLKPL
     L