ID   BIOY_LYSSH              Reviewed;         196 AA.
AC   P22819; P19207;
DT   01-AUG-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-AUG-1991, sequence version 1.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=Probable biotin transporter BioY;
GN   Name=bioY;
OS   Lysinibacillus sphaericus (Bacillus sphaericus).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Lysinibacillus.
OX   NCBI_TaxID=1421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 10208 / DSM 5019 / NBRC 3525 / NCIMB 11935 / NRS 966 / 1911;
RX   PubMed=2110099; DOI=10.1016/0378-1119(90)90496-e;
RA   Gloeckler R., Ohsawa I., Speck D., Ledoux C., Bernard S., Zinsius M.,
RA   Villeval D., Kisou T., Kamogawa K., Lemoine Y.;
RT   "Cloning and characterization of the Bacillus sphaericus genes controlling
RT   the bioconversion of pimelate into dethiobiotin.";
RL   Gene 87:63-70(1990).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 104-196.
RC   STRAIN=T-178-367;
RX   PubMed=2507401; DOI=10.1016/0378-1119(89)90248-5;
RA   Ohsawa I., Speck D., Kisou T., Hayakawa K., Zinsius M., Gloeckler R.,
RA   Lemoine Y., Kamogawa K.;
RT   "Cloning of the biotin synthetase gene from Bacillus sphaericus and
RT   expression in Escherichia coli and Bacilli.";
RL   Gene 80:39-48(1989).
CC   -!- FUNCTION: Probable biotin transporter. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the BioY family. {ECO:0000305}.
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DR   EMBL; M29292; AAB02326.1; -; Genomic_DNA.
DR   EMBL; M27867; AAA22267.1; -; Genomic_DNA.
DR   PIR; JQ0508; JQ0508.
DR   RefSeq; WP_024361130.1; NZ_UFSZ01000001.1.
DR   AlphaFoldDB; P22819; -.
DR   SMR; P22819; -.
DR   GeneID; 48276409; -.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015225; F:biotin transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR003784; BioY.
DR   PANTHER; PTHR34295; PTHR34295; 1.
DR   Pfam; PF02632; BioY; 1.
DR   PIRSF; PIRSF016661; BioY; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..196
FT                   /note="Probable biotin transporter BioY"
FT                   /id="PRO_0000144145"
FT   TRANSMEM        8..28
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        30..50
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        59..79
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        81..101
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        114..134
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        150..170
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   196 AA;  21347 MW;  10DD21705CA084EB CRC64;
     MLKQQSTLSL VMIAMFAALT AVGAFIKIPL PLVPFTLQIV FVFLAGCLLG GRNGFQSQLV
     YIGIGLVGLP VFTQGGGITY VLQPTFGYLI GFALAALVIG YMIDRVESPT KKHFIVANII
     GLIIIYAVAV PYLYVALNVW LNMKSSWSHV FLVGFVNSIV ADFCLAIASA LLAERLYKVF
     RSARAIKLVQ IEKENV