ID   BIOY_METTH              Reviewed;         157 AA.
AC   O26990;
DT   30-MAY-2000, integrated into UniProtKB/Swiss-Prot.
DT   01-JAN-1998, sequence version 1.
DT   25-MAY-2022, entry version 108.
DE   RecName: Full=Probable biotin transporter BioY;
GN   Name=bioY; OrderedLocusNames=MTH_905;
OS   Methanothermobacter thermautotrophicus (strain ATCC 29096 / DSM 1053 / JCM
OS   10044 / NBRC 100330 / Delta H) (Methanobacterium thermoautotrophicum).
OC   Archaea; Euryarchaeota; Methanomada group; Methanobacteria;
OC   Methanobacteriales; Methanobacteriaceae; Methanothermobacter.
OX   NCBI_TaxID=187420;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29096 / DSM 1053 / JCM 10044 / NBRC 100330 / Delta H;
RX   PubMed=9371463; DOI=10.1128/jb.179.22.7135-7155.1997;
RA   Smith D.R., Doucette-Stamm L.A., Deloughery C., Lee H.-M., Dubois J.,
RA   Aldredge T., Bashirzadeh R., Blakely D., Cook R., Gilbert K., Harrison D.,
RA   Hoang L., Keagle P., Lumm W., Pothier B., Qiu D., Spadafora R., Vicare R.,
RA   Wang Y., Wierzbowski J., Gibson R., Jiwani N., Caruso A., Bush D.,
RA   Safer H., Patwell D., Prabhakar S., McDougall S., Shimer G., Goyal A.,
RA   Pietrovski S., Church G.M., Daniels C.J., Mao J.-I., Rice P., Noelling J.,
RA   Reeve J.N.;
RT   "Complete genome sequence of Methanobacterium thermoautotrophicum deltaH:
RT   functional analysis and comparative genomics.";
RL   J. Bacteriol. 179:7135-7155(1997).
CC   -!- FUNCTION: Probable biotin transporter. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000305}; Multi-pass membrane
CC       protein {ECO:0000305}.
CC   -!- SIMILARITY: Belongs to the BioY family. {ECO:0000305}.
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DR   EMBL; AE000666; AAB85403.1; -; Genomic_DNA.
DR   PIR; B69221; B69221.
DR   AlphaFoldDB; O26990; -.
DR   SMR; O26990; -.
DR   STRING; 187420.MTH_905; -.
DR   EnsemblBacteria; AAB85403; AAB85403; MTH_905.
DR   KEGG; mth:MTH_905; -.
DR   PATRIC; fig|187420.15.peg.890; -.
DR   HOGENOM; CLU_077931_1_1_2; -.
DR   OMA; AGYLWSY; -.
DR   Proteomes; UP000005223; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015225; F:biotin transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR003784; BioY.
DR   PANTHER; PTHR34295; PTHR34295; 1.
DR   Pfam; PF02632; BioY; 1.
DR   PIRSF; PIRSF016661; BioY; 1.
PE   3: Inferred from homology;
KW   Cell membrane; Membrane; Reference proteome; Transmembrane;
KW   Transmembrane helix; Transport.
FT   CHAIN           1..157
FT                   /note="Probable biotin transporter BioY"
FT                   /id="PRO_0000144148"
FT   TRANSMEM        10..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        38..58
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        76..96
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        104..124
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   157 AA;  16827 MW;  3C9CA582BBAFB76E CRC64;
     MSGVILGRYW GGLSQLIYVI IGAAGVPWFA DMSGGPEVLL GATGGYLLGF ILAALLLGHF
     VDRHIRARKF TPMLGLMTIA NFGLIYIPGL VVLGLWSLKT QGTLPGPWEL LVMGLLPFIP
     GDILKITGAA ALTRAITPKE PYGEEIDIQK AEGWRVP