ID   BIOY_RHIEC              Reviewed;         187 AA.
AC   Q2KBP7; Q6GUB0;
DT   21-MAR-2012, integrated into UniProtKB/Swiss-Prot.
DT   07-MAR-2006, sequence version 1.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=Biotin transporter BioY;
DE   AltName: Full=Biotin ECF transporter S component BioY;
GN   Name=bioY; OrderedLocusNames=RHE_CH00928;
OS   Rhizobium etli (strain CFN 42 / ATCC 51251).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Hyphomicrobiales;
OC   Rhizobiaceae; Rhizobium/Agrobacterium group; Rhizobium.
OX   NCBI_TaxID=347834;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA], FUNCTION IN BIOTIN UPTAKE, SUBUNIT,
RP   INDUCTION, AND DISRUPTION PHENOTYPE.
RC   STRAIN=CE3;
RX   PubMed=16099603; DOI=10.1016/j.femsle.2005.07.020;
RA   Guillen-Navarro K., Araiza G., Garcia-de los Santos A., Mora Y., Dunn M.F.;
RT   "The Rhizobium etli bioMNY operon is involved in biotin transport.";
RL   FEMS Microbiol. Lett. 250:209-219(2005).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CFN 42 / ATCC 51251;
RX   PubMed=16505379; DOI=10.1073/pnas.0508502103;
RA   Gonzalez V., Santamaria R.I., Bustos P., Hernandez-Gonzalez I.,
RA   Medrano-Soto A., Moreno-Hagelsieb G., Janga S.C., Ramirez M.A.,
RA   Jimenez-Jacinto V., Collado-Vides J., Davila G.;
RT   "The partitioned Rhizobium etli genome: genetic and metabolic redundancy in
RT   seven interacting replicons.";
RL   Proc. Natl. Acad. Sci. U.S.A. 103:3834-3839(2006).
CC   -!- FUNCTION: Involved in biotin uptake. {ECO:0000269|PubMed:16099603}.
CC   -!- SUBUNIT: Part of a biotin transporter complex composed of BioM, BioN
CC       and BioY. {ECO:0000305|PubMed:16099603}.
CC   -!- SUBCELLULAR LOCATION: Cell inner membrane {ECO:0000305}; Multi-pass
CC       membrane protein {ECO:0000305}.
CC   -!- INDUCTION: Expression is repressed by biotin.
CC       {ECO:0000269|PubMed:16099603}.
CC   -!- DISRUPTION PHENOTYPE: Mutant exhibits lower biotin uptake and has a
CC       diminished capacity to form nodules on bean plants.
CC       {ECO:0000269|PubMed:16099603}.
CC   -!- SIMILARITY: Belongs to the BioY family. {ECO:0000305}.
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DR   EMBL; AY644481; AAT52198.1; -; Genomic_DNA.
DR   EMBL; CP000133; ABC89739.1; -; Genomic_DNA.
DR   RefSeq; WP_011424275.1; NC_007761.1.
DR   AlphaFoldDB; Q2KBP7; -.
DR   SMR; Q2KBP7; -.
DR   STRING; 347834.RHE_CH00928; -.
DR   TCDB; 2.A.88.1.1; the vitamin uptake transporter (vut) family.
DR   TCDB; 3.A.1.25.1; the atp-binding cassette (abc) superfamily.
DR   EnsemblBacteria; ABC89739; ABC89739; RHE_CH00928.
DR   GeneID; 58688370; -.
DR   GeneID; 61479382; -.
DR   KEGG; ret:RHE_CH00928; -.
DR   eggNOG; COG1268; Bacteria.
DR   HOGENOM; CLU_077931_0_1_5; -.
DR   OMA; AGYLWSY; -.
DR   Proteomes; UP000001936; Chromosome.
DR   GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0015225; F:biotin transmembrane transporter activity; IEA:InterPro.
DR   InterPro; IPR003784; BioY.
DR   PANTHER; PTHR34295; PTHR34295; 1.
DR   Pfam; PF02632; BioY; 1.
DR   PIRSF; PIRSF016661; BioY; 1.
PE   1: Evidence at protein level;
KW   Cell inner membrane; Cell membrane; Membrane; Reference proteome;
KW   Transmembrane; Transmembrane helix; Transport.
FT   CHAIN           1..187
FT                   /note="Biotin transporter BioY"
FT                   /id="PRO_0000416407"
FT   TRANSMEM        10..30
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        53..73
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        78..98
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        120..140
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   TRANSMEM        152..172
FT                   /note="Helical"
FT                   /evidence="ECO:0000255"
FT   CONFLICT        180..187
FT                   /note="YPLLPARA -> FPCCGARLSA (in Ref. 1; AAT52198)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   187 AA;  18970 MW;  6931DF2806E6F51F CRC64;
     MSTRDLVLTA LFAAIIVALG LLPPISLGFI PVPITAQSLG VMMAGVVLGA RRGAIAVLIV
     LLLVAIGLPV LSGGRGGLAI FASPTAGFLV GWIFGAFVTG YLSERLVNHG QSGLVQTVSF
     FLAAMIGGIV VLYAFGITYL ATVAGLGFTK AFVGSMAFIP GDVIKAVVAA LLGRAVMVGY
     PLLPARA