ID   BIPC_BURP0              Reviewed;         419 AA.
AC   A3P6Z6;
DT   22-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   22-JUL-2008, sequence version 2.
DT   03-AUG-2022, entry version 60.
DE   RecName: Full=Effector protein BipC;
GN   Name=bipC; OrderedLocusNames=BURPS1106A_A2073;
OS   Burkholderia pseudomallei (strain 1106a).
OC   Bacteria; Proteobacteria; Betaproteobacteria; Burkholderiales;
OC   Burkholderiaceae; Burkholderia; pseudomallei group.
OX   NCBI_TaxID=357348;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=1106a;
RX   PubMed=20333227; DOI=10.1093/gbe/evq003;
RA   Losada L., Ronning C.M., DeShazer D., Woods D., Fedorova N., Kim H.S.,
RA   Shabalina S.A., Pearson T.R., Brinkac L., Tan P., Nandi T., Crabtree J.,
RA   Badger J., Beckstrom-Sternberg S., Saqib M., Schutzer S.E., Keim P.,
RA   Nierman W.C.;
RT   "Continuing evolution of Burkholderia mallei through genome reduction and
RT   large-scale rearrangements.";
RL   Genome Biol. Evol. 2:102-116(2010).
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000250}. Note=Secreted via the bsa
CC       type III secretion system. {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the invasin protein C family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=ABN93279.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; CP000573; ABN93279.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_004551891.1; NC_009078.1.
DR   AlphaFoldDB; A3P6Z6; -.
DR   EnsemblBacteria; ABN93279; ABN93279; BURPS1106A_A2073.
DR   GeneID; 56530060; -.
DR   KEGG; bpl:BURPS1106A_A2073; -.
DR   HOGENOM; CLU_661703_0_0_4; -.
DR   PHI-base; PHI:6552; -.
DR   Proteomes; UP000006738; Chromosome II.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   InterPro; IPR005427; BacInvasinC.
DR   Pfam; PF09599; IpaC_SipC; 1.
DR   TIGRFAMs; TIGR02101; IpaC_SipC; 1.
PE   3: Inferred from homology;
KW   Secreted; Virulence.
FT   CHAIN           1..419
FT                   /note="Effector protein BipC"
FT                   /id="PRO_0000343998"
FT   REGION          62..91
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          338..402
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        75..91
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        338..359
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   419 AA;  44250 MW;  D15BA60EFC61A487 CRC64;
     MSIGVQSSGI NISHAGLSRL VDAGKSEQGD KAVRDDGRAL ARADAALAAV VGERVAARRD
     AVAGSGAQRV ELARPKPDAQ TRATDRRTVS GLEREHKRLA ASQTPRVTGM HDALVQRHVS
     LDGAKAAHGE GVKRAAGDAP RAAADAPQRF AFADDKAFDA MLALGAAMQK NVQSDLAMQG
     KLTMLAHDAM MSAAAQDRSI GAAQMTAAIA GGALQATTSL GGAMQQMKSL STKSMSIEKE
     LKPQAELKQF HAEQALELRG INKPVLSNDE VSHVKIKRDT GETVRHEIDH GGERMSDEHA
     SVLAQEAPAR QHRIDMHGMR HEENLVKAGR QQMKGDLLQS GGQIGKNQID GASAQQQGAD
     RAEQKEDENA QQTAMAAAST RDEAAHRSRE AAQKAIDAAK SQVANDNAVA AQVAGNLRT