ID   SYF2_CAEBR              Reviewed;         233 AA.
AC   Q612R3; A8XPK9;
DT   19-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT   19-SEP-2006, sequence version 2.
DT   25-MAY-2022, entry version 56.
DE   RecName: Full=Pre-mRNA-splicing factor syf-2;
GN   Name=syf-2 {ECO:0000312|WormBase:CBG16608};
GN   ORFNames=CBG16608 {ECO:0000312|WormBase:CBG16608};
OS   Caenorhabditis briggsae.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6238;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AF16;
RX   PubMed=14624247; DOI=10.1371/journal.pbio.0000045;
RA   Stein L.D., Bao Z., Blasiar D., Blumenthal T., Brent M.R., Chen N.,
RA   Chinwalla A., Clarke L., Clee C., Coghlan A., Coulson A., D'Eustachio P.,
RA   Fitch D.H.A., Fulton L.A., Fulton R.E., Griffiths-Jones S., Harris T.W.,
RA   Hillier L.W., Kamath R., Kuwabara P.E., Mardis E.R., Marra M.A.,
RA   Miner T.L., Minx P., Mullikin J.C., Plumb R.W., Rogers J., Schein J.E.,
RA   Sohrmann M., Spieth J., Stajich J.E., Wei C., Willey D., Wilson R.K.,
RA   Durbin R.M., Waterston R.H.;
RT   "The genome sequence of Caenorhabditis briggsae: a platform for comparative
RT   genomics.";
RL   PLoS Biol. 1:166-192(2003).
CC   -!- FUNCTION: May be involved in pre-mRNA splicing.
CC       {ECO:0000250|UniProtKB:P53277}.
CC   -!- SUBUNIT: May be part of a spliceosome complex.
CC       {ECO:0000250|UniProtKB:P53277}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:O95926}.
CC   -!- SIMILARITY: Belongs to the SYF2 family. {ECO:0000305}.
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DR   EMBL; HE600949; CAP34530.2; -; Genomic_DNA.
DR   AlphaFoldDB; Q612R3; -.
DR   SMR; Q612R3; -.
DR   STRING; 6238.CBG16608; -.
DR   PRIDE; Q612R3; -.
DR   EnsemblMetazoa; CBG16608.1; CBG16608.1; WBGene00036500.
DR   WormBase; CBG16608; CBP25827; WBGene00036500; Cbr-syf-2.
DR   eggNOG; KOG2609; Eukaryota.
DR   HOGENOM; CLU_051065_3_0_1; -.
DR   InParanoid; Q612R3; -.
DR   OMA; RRRMHND; -.
DR   OrthoDB; 1565402at2759; -.
DR   Proteomes; UP000008549; Chromosome III.
DR   GO; GO:0071013; C:catalytic step 2 spliceosome; IBA:GO_Central.
DR   GO; GO:0071014; C:post-mRNA release spliceosomal complex; IBA:GO_Central.
DR   GO; GO:0000974; C:Prp19 complex; IBA:GO_Central.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   InterPro; IPR013260; mRNA_splic_SYF2.
DR   PANTHER; PTHR13264; PTHR13264; 1.
DR   Pfam; PF08231; SYF2; 1.
PE   3: Inferred from homology;
KW   Coiled coil; mRNA processing; mRNA splicing; Nucleus; Reference proteome;
KW   Spliceosome.
FT   CHAIN           1..233
FT                   /note="Pre-mRNA-splicing factor syf-2"
FT                   /id="PRO_0000250383"
FT   REGION          1..80
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          95..119
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          18..77
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        1..19
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        20..80
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        95..112
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   233 AA;  27628 MW;  1A6205861E046A38 CRC64;
     MSDSEQTSSG TASSGSKMKD FNQRFRDLHK MRQKARKENH AQVVEEDRRK KLPKNFEAKK
     ERDQWQVKEL QDRKEAEDKG LDYERVRSLE MSADVTEKLE QKRKRKKNPD QGFASYEDMT
     LRQHTRLTAA LDPDLESYKK MKECVGGDQF YPTADTLIHG NHYPTTSAMD RLVKDVHGQV
     KRREQYHRRR LYDPDAPIDY INEKNKKFNK KLDKYYGKYT EDIKDDLERG TAI