SYF2_GEKJA
ID SYF2_GEKJA Reviewed; 249 AA.
AC Q6DV01;
DT 19-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT 16-AUG-2004, sequence version 1.
DT 25-MAY-2022, entry version 36.
DE RecName: Full=Pre-mRNA-splicing factor syf2;
GN Name=syf2; Synonyms=GekBS028P;
OS Gekko japonicus (Schlegel's Japanese gecko).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC Lepidosauria; Squamata; Bifurcata; Gekkota; Gekkonidae; Gekkoninae; Gekko.
OX NCBI_TaxID=146911;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain;
RA Liu Y., Gu X., Ding F., Liu M., Yao D., Shen M.;
RT "Analysis of expressed sequence tags and cloning of full length cDNA from
RT brain and spinal cord cDNA library in Gecko.";
RL Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in pre-mRNA splicing as component of the
CC spliceosome. {ECO:0000250|UniProtKB:O95926}.
CC -!- SUBUNIT: Identified in the spliceosome C complex.
CC {ECO:0000250|UniProtKB:O95926}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:O95926}.
CC -!- SIMILARITY: Belongs to the SYF2 family. {ECO:0000305}.
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DR EMBL; AY641849; AAT68230.1; -; mRNA.
DR RefSeq; NP_001310429.1; NM_001323500.1.
DR AlphaFoldDB; Q6DV01; -.
DR SMR; Q6DV01; -.
DR GeneID; 107110818; -.
DR KEGG; gja:107110818; -.
DR CTD; 25949; -.
DR OrthoDB; 1565402at2759; -.
DR GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR GO; GO:0071007; C:U2-type catalytic step 2 spliceosome; ISS:UniProtKB.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; ISS:UniProtKB.
DR InterPro; IPR013260; mRNA_splic_SYF2.
DR PANTHER; PTHR13264; PTHR13264; 1.
DR Pfam; PF08231; SYF2; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; mRNA processing; mRNA splicing; Nucleus; Spliceosome.
FT CHAIN 1..249
FT /note="Pre-mRNA-splicing factor syf2"
FT /id="PRO_0000250380"
FT REGION 1..22
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 34..95
FT /evidence="ECO:0000255"
SQ SEQUENCE 249 AA; 29317 MW; 54F64709D5153798 CRC64;
MAAVEENEAP SPVMAITGIS EDPASIAAED TAAQKREEHL RKFRELHLKR NEARKLNHQE
VVEEDKRLKL PANWEAKKSR LEWELKVEEK KKECVAKGED YERVKLLEIS AEDAERFERK
RKKRNPDLGF SDYAAAQMRQ YQRLTRQIKP DLEKYAKLRE ESGEEFYPTS NSLLHGTHVP
CKEGVDKMVE DLEKQIQKRE KYSRRRPYND DADIDYINER NAKFNKKAER FYGKYTAEIK
QNLERGTAV