ID   SYF2_KLULA              Reviewed;         221 AA.
AC   Q6CPI4;
DT   13-SEP-2005, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 69.
DE   RecName: Full=Pre-mRNA-splicing factor SYF2;
GN   Name=SYF2; OrderedLocusNames=KLLA0E04565g;
OS   Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS   NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Involved in pre-mRNA splicing. {ECO:0000250}.
CC   -!- SUBUNIT: Associated with the spliceosome. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the SYF2 family. {ECO:0000305}.
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DR   EMBL; CR382125; CAG99242.1; -; Genomic_DNA.
DR   RefSeq; XP_454155.1; XM_454155.1.
DR   AlphaFoldDB; Q6CPI4; -.
DR   SMR; Q6CPI4; -.
DR   STRING; 28985.XP_454155.1; -.
DR   EnsemblFungi; CAG99242; CAG99242; KLLA0_E04643g.
DR   GeneID; 2894082; -.
DR   KEGG; kla:KLLA0_E04643g; -.
DR   eggNOG; KOG2609; Eukaryota.
DR   HOGENOM; CLU_114239_0_0_1; -.
DR   InParanoid; Q6CPI4; -.
DR   OMA; YSIREYE; -.
DR   Proteomes; UP000000598; Chromosome E.
DR   GO; GO:0005681; C:spliceosomal complex; IEA:UniProtKB-KW.
DR   GO; GO:0006397; P:mRNA processing; IEA:UniProtKB-KW.
DR   GO; GO:0008380; P:RNA splicing; IEA:UniProtKB-KW.
DR   InterPro; IPR013260; mRNA_splic_SYF2.
DR   Pfam; PF08231; SYF2; 1.
PE   3: Inferred from homology;
KW   Coiled coil; mRNA processing; mRNA splicing; Nucleus; Reference proteome;
KW   Spliceosome.
FT   CHAIN           1..221
FT                   /note="Pre-mRNA-splicing factor SYF2"
FT                   /id="PRO_0000072376"
FT   REGION          72..98
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          34..63
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   221 AA;  25869 MW;  00FAA597DAD7697E CRC64;
     MNILRYLPGD RKCSPYLNAT NHIVNWTQAD NKYSKMNDLM EIEKKLKSLR KQKVEVSIRN
     KKAIIAEEKK NSERRVYSMA DDGEDKARSN KSEPEDPIKL ANYSIREYEK WEAKTQNSRH
     NKSVMGDFQT IAKNSYKKEV DALPKDISHP LKGGITEDGK VQVEDNPELV EKMVNDLNER
     SKKRYMVRKQ KLDKQNKINL DDGFINDKNK RFNAKLNSEF K