SYF2_XENLA
ID SYF2_XENLA Reviewed; 240 AA.
AC Q8AVQ6;
DT 19-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 50.
DE RecName: Full=Pre-mRNA-splicing factor syf2;
GN Name=syf2;
OS Xenopus laevis (African clawed frog).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus.
OX NCBI_TaxID=8355;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Embryo;
RG NIH - Xenopus Gene Collection (XGC) project;
RL Submitted (DEC-2002) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Involved in pre-mRNA splicing as component of the
CC spliceosome. {ECO:0000250|UniProtKB:O95926}.
CC -!- SUBUNIT: Identified in the spliceosome C complex.
CC {ECO:0000250|UniProtKB:O95926}.
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:O95926}.
CC -!- SIMILARITY: Belongs to the SYF2 family. {ECO:0000305}.
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DR EMBL; BC041520; AAH41520.1; -; mRNA.
DR RefSeq; NP_001079405.1; NM_001085936.1.
DR AlphaFoldDB; Q8AVQ6; -.
DR SMR; Q8AVQ6; -.
DR DNASU; 379092; -.
DR GeneID; 379092; -.
DR KEGG; xla:379092; -.
DR CTD; 379092; -.
DR Xenbase; XB-GENE-920851; syf2.S.
DR OrthoDB; 1565402at2759; -.
DR Proteomes; UP000186698; Chromosome 6S.
DR Bgee; 379092; Expressed in gastrula and 19 other tissues.
DR GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR GO; GO:0071007; C:U2-type catalytic step 2 spliceosome; ISS:UniProtKB.
DR GO; GO:0000398; P:mRNA splicing, via spliceosome; ISS:UniProtKB.
DR InterPro; IPR013260; mRNA_splic_SYF2.
DR PANTHER; PTHR13264; PTHR13264; 1.
DR Pfam; PF08231; SYF2; 1.
PE 2: Evidence at transcript level;
KW Coiled coil; mRNA processing; mRNA splicing; Nucleus; Reference proteome;
KW Spliceosome.
FT CHAIN 1..240
FT /note="Pre-mRNA-splicing factor syf2"
FT /id="PRO_0000250381"
FT REGION 1..25
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 63..91
FT /evidence="ECO:0000255"
SQ SEQUENCE 240 AA; 28477 MW; DD241F8949EBD50C CRC64;
MDKEKAEVSP EEESAPASAE DLAAQKREAR LRKFRELHLK TNEARKLNHQ EVVEEDKRQK
LPSNWEARKA RLEWELKNEE KKRECAANGV DFERAKLLEI SAEDAERWER KKKRKNPDLG
FSDYAAAQLR QYQRLTKQIK PDMEEYEMEK EKQGELFYPT SDSLYHGTHV PSQSGIDRMV
TDLEKQIEKR EKYSRRRAYN DDADIDYINE RNAKFNKKAE RFYGKYTAEI KQNLERGTAV