ID   SYF2_XENTR              Reviewed;         249 AA.
AC   Q28G05; Q5PPP9; Q688C6;
DT   19-SEP-2006, integrated into UniProtKB/Swiss-Prot.
DT   04-APR-2006, sequence version 1.
DT   03-AUG-2022, entry version 58.
DE   RecName: Full=Pre-mRNA-splicing factor syf2;
GN   Name=syf2; ORFNames=TGas131i06.1;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RA   Qin S., Dors M., Johnson E., Bloom S., Hood L., Rowen L.;
RT   "Sequence of Xenopus tropicalis development genes.";
RL   Submitted (SEP-2004) to the EMBL/GenBank/DDBJ databases.
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Gastrula;
RG   Sanger Xenopus tropicalis EST/cDNA project;
RL   Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 5-249.
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (DEC-2004) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Involved in pre-mRNA splicing as component of the
CC       spliceosome. {ECO:0000250|UniProtKB:O95926}.
CC   -!- SUBUNIT: Identified in the spliceosome C complex.
CC       {ECO:0000250|UniProtKB:O95926}.
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000250|UniProtKB:O95926}.
CC   -!- SIMILARITY: Belongs to the SYF2 family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAU12852.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AC151465; AAU12852.1; ALT_INIT; Genomic_DNA.
DR   EMBL; CR761644; CAJ83779.1; -; mRNA.
DR   EMBL; BC087564; AAH87564.1; -; mRNA.
DR   RefSeq; NP_001032340.1; NM_001037263.1.
DR   AlphaFoldDB; Q28G05; -.
DR   SMR; Q28G05; -.
DR   PaxDb; Q28G05; -.
DR   Ensembl; ENSXETT00000049327; ENSXETP00000049327; ENSXETG00000022797.
DR   GeneID; 496706; -.
DR   KEGG; xtr:496706; -.
DR   CTD; 25949; -.
DR   Xenbase; XB-GENE-920839; syf2.
DR   eggNOG; KOG2609; Eukaryota.
DR   InParanoid; Q28G05; -.
DR   OrthoDB; 1565402at2759; -.
DR   Reactome; R-XTR-72163; mRNA Splicing - Major Pathway.
DR   Proteomes; UP000008143; Chromosome 6.
DR   Proteomes; UP000790000; Unplaced.
DR   Bgee; ENSXETG00000022797; Expressed in ovary and 15 other tissues.
DR   GO; GO:0071013; C:catalytic step 2 spliceosome; IBA:GO_Central.
DR   GO; GO:0005634; C:nucleus; ISS:UniProtKB.
DR   GO; GO:0071014; C:post-mRNA release spliceosomal complex; IBA:GO_Central.
DR   GO; GO:0000974; C:Prp19 complex; IBA:GO_Central.
DR   GO; GO:0071007; C:U2-type catalytic step 2 spliceosome; ISS:UniProtKB.
DR   GO; GO:0000398; P:mRNA splicing, via spliceosome; ISS:UniProtKB.
DR   InterPro; IPR013260; mRNA_splic_SYF2.
DR   PANTHER; PTHR13264; PTHR13264; 1.
DR   Pfam; PF08231; SYF2; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; mRNA processing; mRNA splicing; Nucleus; Reference proteome;
KW   Spliceosome.
FT   CHAIN           1..249
FT                   /note="Pre-mRNA-splicing factor syf2"
FT                   /id="PRO_0000250382"
FT   REGION          1..36
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          72..100
FT                   /evidence="ECO:0000255"
FT   COMPBIAS        1..25
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   249 AA;  29298 MW;  AAA6C51BCD0E3B26 CRC64;
     MKSPSAAVTE DNETAGVSSK AESPPASTED LAAQKREARL RKFRELHLKT NEARKLNHQE
     VVEEDKRQKL PSNWEARKAR LEWELKEEEK KRECAANGVD YERAKLLEIS AEDAERWERK
     KKRKNPDLGF SDYAAAQLRQ YQRLTKQIKP DMEEYEMEKQ KQGEMFYPTS ESLYHGTHIP
     SQSGIDRMVT DLEKQIEKRE KYSRRRAYND DADIDYINER NAKFNKKAER FYGKYTAEIK
     QNLERGTAV