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BIVM_MOUSE
ID   BIVM_MOUSE              Reviewed;         502 AA.
AC   Q8CBX9; Q8CCP3;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   03-AUG-2022, entry version 97.
DE   RecName: Full=Basic immunoglobulin-like variable motif-containing protein;
GN   Name=Bivm;
OS   Mus musculus (Mouse).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC   Murinae; Mus; Mus.
OX   NCBI_TaxID=10090;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=C57BL/6J; TISSUE=Diencephalon, and Olfactory bulb;
RX   PubMed=16141072; DOI=10.1126/science.1112014;
RA   Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA   Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA   Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA   Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA   Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA   Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA   Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA   Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA   Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA   Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA   Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA   Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA   Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA   Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA   Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA   Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA   Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA   Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA   Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA   Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA   Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA   Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA   Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA   Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA   Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA   van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA   Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA   Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA   Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA   Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA   Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA   Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA   Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA   Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT   "The transcriptional landscape of the mammalian genome.";
RL   Science 309:1559-1563(2005).
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the BIVM family. {ECO:0000305}.
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DR   EMBL; AK032375; BAC27843.1; -; mRNA.
DR   EMBL; AK034329; BAC28676.1; -; mRNA.
DR   CCDS; CCDS14930.1; -.
DR   RefSeq; NP_653141.3; NM_144558.4.
DR   RefSeq; XP_006496061.2; XM_006495998.3.
DR   RefSeq; XP_006496063.1; XM_006496000.2.
DR   RefSeq; XP_006496065.1; XM_006496002.2.
DR   RefSeq; XP_006496067.1; XM_006496004.3.
DR   RefSeq; XP_017176210.1; XM_017320721.1.
DR   AlphaFoldDB; Q8CBX9; -.
DR   STRING; 10090.ENSMUSP00000110357; -.
DR   iPTMnet; Q8CBX9; -.
DR   PhosphoSitePlus; Q8CBX9; -.
DR   PaxDb; Q8CBX9; -.
DR   PRIDE; Q8CBX9; -.
DR   ProteomicsDB; 273495; -.
DR   DNASU; 246229; -.
DR   Ensembl; ENSMUST00000035991; ENSMUSP00000041964; ENSMUSG00000041684.
DR   Ensembl; ENSMUST00000114709; ENSMUSP00000110357; ENSMUSG00000041684.
DR   GeneID; 246229; -.
DR   KEGG; mmu:246229; -.
DR   UCSC; uc007awd.2; mouse.
DR   CTD; 54841; -.
DR   MGI; MGI:2179809; Bivm.
DR   VEuPathDB; HostDB:ENSMUSG00000041684; -.
DR   eggNOG; ENOG502QUM8; Eukaryota.
DR   GeneTree; ENSGT00510000048601; -.
DR   HOGENOM; CLU_041921_1_0_1; -.
DR   InParanoid; Q8CBX9; -.
DR   OMA; CDFRGRV; -.
DR   OrthoDB; 421443at2759; -.
DR   PhylomeDB; Q8CBX9; -.
DR   TreeFam; TF331304; -.
DR   BioGRID-ORCS; 246229; 1 hit in 71 CRISPR screens.
DR   ChiTaRS; Bivm; mouse.
DR   PRO; PR:Q8CBX9; -.
DR   Proteomes; UP000000589; Chromosome 1.
DR   RNAct; Q8CBX9; protein.
DR   Bgee; ENSMUSG00000041684; Expressed in renal medulla interstitium and 213 other tissues.
DR   ExpressionAtlas; Q8CBX9; baseline and differential.
DR   Genevisible; Q8CBX9; MM.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   InterPro; IPR038819; BIVM.
DR   PANTHER; PTHR16171:SF9; PTHR16171:SF9; 1.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Nucleus; Reference proteome.
FT   CHAIN           1..502
FT                   /note="Basic immunoglobulin-like variable motif-containing
FT                   protein"
FT                   /id="PRO_0000328956"
FT   REGION          1..32
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          438..460
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        356
FT                   /note="W -> C (in Ref. 1; BAC27843)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        381
FT                   /note="L -> V (in Ref. 1; BAC27843)"
FT                   /evidence="ECO:0000305"
FT   CONFLICT        388
FT                   /note="F -> L (in Ref. 1; BAC27843)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   502 AA;  56622 MW;  79420B93221D9378 CRC64;
     MPNATEAGKA TDPGHGEHTS ENKSPEEGLQ GAVPSFYTSA SEAPIAPRGD GHYPSSCPVT
     HTREKIYAIC SDYAFLNQAT SVYKTPSLTR SACLPDNTSL SAGNTTRYIG ISTSTSEIIY
     NEENNLENLS TGMGKLPLAW EIDKSEFDGV TTNLIHKSGN VKKQFSKKKT SDKKGRHQRE
     CLHYSPLDDV KQRKVLDLRR WYCISRPQYK TSCGISSLIS CWNFLYSIMG AGNLPPITQE
     EALHILGFQP PFEDIRFGPF TGNTTLMRWF RQINDHFHVK GCSYVLYKPH GKNKTAGETA
     PGALSKLTRG LKDESLAYIY HCQNHYFCPI GFEATPVKAN KAFSRGPLSS QEVEYWILIG
     ESSRKHPAIH CKRWADIVTD LNTQNPEFLD IRHLERGLQF RKTKKVGGNL HCIIAFQRLS
     WQRFGFWNFP FGTITQESQH PTHVPGIAKS ESEDNISKKQ HGRLGRSFSA SFHQDSAWKN
     MSSIHERRNS GYHSFRDYNG ND
 
 
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