BIVM_MOUSE
ID BIVM_MOUSE Reviewed; 502 AA.
AC Q8CBX9; Q8CCP3;
DT 08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 97.
DE RecName: Full=Basic immunoglobulin-like variable motif-containing protein;
GN Name=Bivm;
OS Mus musculus (Mouse).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Mus; Mus.
OX NCBI_TaxID=10090;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=C57BL/6J; TISSUE=Diencephalon, and Olfactory bulb;
RX PubMed=16141072; DOI=10.1126/science.1112014;
RA Carninci P., Kasukawa T., Katayama S., Gough J., Frith M.C., Maeda N.,
RA Oyama R., Ravasi T., Lenhard B., Wells C., Kodzius R., Shimokawa K.,
RA Bajic V.B., Brenner S.E., Batalov S., Forrest A.R., Zavolan M., Davis M.J.,
RA Wilming L.G., Aidinis V., Allen J.E., Ambesi-Impiombato A., Apweiler R.,
RA Aturaliya R.N., Bailey T.L., Bansal M., Baxter L., Beisel K.W., Bersano T.,
RA Bono H., Chalk A.M., Chiu K.P., Choudhary V., Christoffels A.,
RA Clutterbuck D.R., Crowe M.L., Dalla E., Dalrymple B.P., de Bono B.,
RA Della Gatta G., di Bernardo D., Down T., Engstrom P., Fagiolini M.,
RA Faulkner G., Fletcher C.F., Fukushima T., Furuno M., Futaki S.,
RA Gariboldi M., Georgii-Hemming P., Gingeras T.R., Gojobori T., Green R.E.,
RA Gustincich S., Harbers M., Hayashi Y., Hensch T.K., Hirokawa N., Hill D.,
RA Huminiecki L., Iacono M., Ikeo K., Iwama A., Ishikawa T., Jakt M.,
RA Kanapin A., Katoh M., Kawasawa Y., Kelso J., Kitamura H., Kitano H.,
RA Kollias G., Krishnan S.P., Kruger A., Kummerfeld S.K., Kurochkin I.V.,
RA Lareau L.F., Lazarevic D., Lipovich L., Liu J., Liuni S., McWilliam S.,
RA Madan Babu M., Madera M., Marchionni L., Matsuda H., Matsuzawa S., Miki H.,
RA Mignone F., Miyake S., Morris K., Mottagui-Tabar S., Mulder N., Nakano N.,
RA Nakauchi H., Ng P., Nilsson R., Nishiguchi S., Nishikawa S., Nori F.,
RA Ohara O., Okazaki Y., Orlando V., Pang K.C., Pavan W.J., Pavesi G.,
RA Pesole G., Petrovsky N., Piazza S., Reed J., Reid J.F., Ring B.Z.,
RA Ringwald M., Rost B., Ruan Y., Salzberg S.L., Sandelin A., Schneider C.,
RA Schoenbach C., Sekiguchi K., Semple C.A., Seno S., Sessa L., Sheng Y.,
RA Shibata Y., Shimada H., Shimada K., Silva D., Sinclair B., Sperling S.,
RA Stupka E., Sugiura K., Sultana R., Takenaka Y., Taki K., Tammoja K.,
RA Tan S.L., Tang S., Taylor M.S., Tegner J., Teichmann S.A., Ueda H.R.,
RA van Nimwegen E., Verardo R., Wei C.L., Yagi K., Yamanishi H.,
RA Zabarovsky E., Zhu S., Zimmer A., Hide W., Bult C., Grimmond S.M.,
RA Teasdale R.D., Liu E.T., Brusic V., Quackenbush J., Wahlestedt C.,
RA Mattick J.S., Hume D.A., Kai C., Sasaki D., Tomaru Y., Fukuda S.,
RA Kanamori-Katayama M., Suzuki M., Aoki J., Arakawa T., Iida J., Imamura K.,
RA Itoh M., Kato T., Kawaji H., Kawagashira N., Kawashima T., Kojima M.,
RA Kondo S., Konno H., Nakano K., Ninomiya N., Nishio T., Okada M., Plessy C.,
RA Shibata K., Shiraki T., Suzuki S., Tagami M., Waki K., Watahiki A.,
RA Okamura-Oho Y., Suzuki H., Kawai J., Hayashizaki Y.;
RT "The transcriptional landscape of the mammalian genome.";
RL Science 309:1559-1563(2005).
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the BIVM family. {ECO:0000305}.
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DR EMBL; AK032375; BAC27843.1; -; mRNA.
DR EMBL; AK034329; BAC28676.1; -; mRNA.
DR CCDS; CCDS14930.1; -.
DR RefSeq; NP_653141.3; NM_144558.4.
DR RefSeq; XP_006496061.2; XM_006495998.3.
DR RefSeq; XP_006496063.1; XM_006496000.2.
DR RefSeq; XP_006496065.1; XM_006496002.2.
DR RefSeq; XP_006496067.1; XM_006496004.3.
DR RefSeq; XP_017176210.1; XM_017320721.1.
DR AlphaFoldDB; Q8CBX9; -.
DR STRING; 10090.ENSMUSP00000110357; -.
DR iPTMnet; Q8CBX9; -.
DR PhosphoSitePlus; Q8CBX9; -.
DR PaxDb; Q8CBX9; -.
DR PRIDE; Q8CBX9; -.
DR ProteomicsDB; 273495; -.
DR DNASU; 246229; -.
DR Ensembl; ENSMUST00000035991; ENSMUSP00000041964; ENSMUSG00000041684.
DR Ensembl; ENSMUST00000114709; ENSMUSP00000110357; ENSMUSG00000041684.
DR GeneID; 246229; -.
DR KEGG; mmu:246229; -.
DR UCSC; uc007awd.2; mouse.
DR CTD; 54841; -.
DR MGI; MGI:2179809; Bivm.
DR VEuPathDB; HostDB:ENSMUSG00000041684; -.
DR eggNOG; ENOG502QUM8; Eukaryota.
DR GeneTree; ENSGT00510000048601; -.
DR HOGENOM; CLU_041921_1_0_1; -.
DR InParanoid; Q8CBX9; -.
DR OMA; CDFRGRV; -.
DR OrthoDB; 421443at2759; -.
DR PhylomeDB; Q8CBX9; -.
DR TreeFam; TF331304; -.
DR BioGRID-ORCS; 246229; 1 hit in 71 CRISPR screens.
DR ChiTaRS; Bivm; mouse.
DR PRO; PR:Q8CBX9; -.
DR Proteomes; UP000000589; Chromosome 1.
DR RNAct; Q8CBX9; protein.
DR Bgee; ENSMUSG00000041684; Expressed in renal medulla interstitium and 213 other tissues.
DR ExpressionAtlas; Q8CBX9; baseline and differential.
DR Genevisible; Q8CBX9; MM.
DR GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR InterPro; IPR038819; BIVM.
DR PANTHER; PTHR16171:SF9; PTHR16171:SF9; 1.
PE 2: Evidence at transcript level;
KW Cytoplasm; Nucleus; Reference proteome.
FT CHAIN 1..502
FT /note="Basic immunoglobulin-like variable motif-containing
FT protein"
FT /id="PRO_0000328956"
FT REGION 1..32
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 438..460
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 356
FT /note="W -> C (in Ref. 1; BAC27843)"
FT /evidence="ECO:0000305"
FT CONFLICT 381
FT /note="L -> V (in Ref. 1; BAC27843)"
FT /evidence="ECO:0000305"
FT CONFLICT 388
FT /note="F -> L (in Ref. 1; BAC27843)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 502 AA; 56622 MW; 79420B93221D9378 CRC64;
MPNATEAGKA TDPGHGEHTS ENKSPEEGLQ GAVPSFYTSA SEAPIAPRGD GHYPSSCPVT
HTREKIYAIC SDYAFLNQAT SVYKTPSLTR SACLPDNTSL SAGNTTRYIG ISTSTSEIIY
NEENNLENLS TGMGKLPLAW EIDKSEFDGV TTNLIHKSGN VKKQFSKKKT SDKKGRHQRE
CLHYSPLDDV KQRKVLDLRR WYCISRPQYK TSCGISSLIS CWNFLYSIMG AGNLPPITQE
EALHILGFQP PFEDIRFGPF TGNTTLMRWF RQINDHFHVK GCSYVLYKPH GKNKTAGETA
PGALSKLTRG LKDESLAYIY HCQNHYFCPI GFEATPVKAN KAFSRGPLSS QEVEYWILIG
ESSRKHPAIH CKRWADIVTD LNTQNPEFLD IRHLERGLQF RKTKKVGGNL HCIIAFQRLS
WQRFGFWNFP FGTITQESQH PTHVPGIAKS ESEDNISKKQ HGRLGRSFSA SFHQDSAWKN
MSSIHERRNS GYHSFRDYNG ND