ID   BJSB2_TRINI             Reviewed;         749 AA.
AC   Q06343;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Basic juvenile hormone-suppressible protein 2;
DE            Short=BJHSP2;
DE   Flags: Precursor;
GN   Name=BJSP-2;
OS   Trichoplusia ni (Cabbage looper).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Lepidoptera; Glossata; Ditrysia; Noctuoidea;
OC   Noctuidae; Plusiinae; Trichoplusia.
OX   NCBI_TaxID=7111;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], AND PROTEIN SEQUENCE OF 15-32.
RX   PubMed=8419330; DOI=10.1016/s0021-9258(18)54072-2;
RA   Jones G., Manczak M., Horn M.;
RT   "Hormonal regulation and properties of a new group of basic hemolymph
RT   proteins expressed during insect metamorphosis.";
RL   J. Biol. Chem. 268:1284-1291(1993).
CC   -!- TISSUE SPECIFICITY: Fat body, and hemolymph of larvae.
CC   -!- DEVELOPMENTAL STAGE: Appears in increasing abundance on days 2 and 3 of
CC       the final metamorphic larval stadium and then declines to a very low
CC       level during day 4 prepupal stage.
CC   -!- INDUCTION: Suppressed by juvenile hormone.
CC   -!- SIMILARITY: Belongs to the hemocyanin family. {ECO:0000305}.
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DR   EMBL; L03281; AAA27883.1; ALT_SEQ; mRNA.
DR   PIR; A45046; A45046.
DR   AlphaFoldDB; Q06343; -.
DR   SMR; Q06343; -.
DR   PRIDE; Q06343; -.
DR   Proteomes; UP000322000; Genome assembly.
DR   GO; GO:0045735; F:nutrient reservoir activity; IEA:UniProtKB-KW.
DR   Gene3D; 1.10.1280.10; -; 1.
DR   Gene3D; 1.20.1370.10; -; 1.
DR   Gene3D; 2.60.40.1520; -; 1.
DR   InterPro; IPR008922; Di-copper_centre_dom_sf.
DR   InterPro; IPR013788; Hemocyanin/hexamerin.
DR   InterPro; IPR000896; Hemocyanin/hexamerin_mid_dom.
DR   InterPro; IPR005203; Hemocyanin_C.
DR   InterPro; IPR037020; Hemocyanin_C_sf.
DR   InterPro; IPR005204; Hemocyanin_N.
DR   InterPro; IPR036697; Hemocyanin_N_sf.
DR   InterPro; IPR014756; Ig_E-set.
DR   PANTHER; PTHR11511; PTHR11511; 1.
DR   Pfam; PF03723; Hemocyanin_C; 1.
DR   Pfam; PF00372; Hemocyanin_M; 1.
DR   Pfam; PF03722; Hemocyanin_N; 1.
DR   PRINTS; PR00187; HAEMOCYANIN.
DR   SUPFAM; SSF48050; SSF48050; 1.
DR   SUPFAM; SSF48056; SSF48056; 1.
DR   SUPFAM; SSF81296; SSF81296; 1.
DR   PROSITE; PS00209; HEMOCYANIN_1; 1.
DR   PROSITE; PS00210; HEMOCYANIN_2; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Reference proteome; Signal; Storage protein.
FT   SIGNAL          1..14
FT                   /evidence="ECO:0000255"
FT   CHAIN           15..749
FT                   /note="Basic juvenile hormone-suppressible protein 2"
FT                   /id="PRO_0000013344"
SQ   SEQUENCE   749 AA;  89613 MW;  18D0F91AE1035EA5 CRC64;
     MRAVLLFVVS LAALRMARPE IDDTTLVTMD IKQRQLVILK LLNHVVEPLM YKDLEELGKN
     FKIEENTDLF TKTDVLKDFI KMRKVGFLPR GEIFTLHVDR QLKEVVTMFH MLYYAKDFTT
     FVKTACWMRL YLNEGMFVYA LTVAVRHRED CKGIILPPPY EIYPYYFVRA DVIQKAYLLK
     MKKGLLDLKL CDFYGIKKTD KDVFIIDENV YDKRVHLNKE DKLRYFTEDI DLNTYYFYFH
     VDYPFWMKDK FMDKMKMRRF ELTYIMYQQI LARYILERLS NGMGMIKDLS WHKTIKKGYW
     PWMKLHNGVE IPVRFDNYVI VRDHNRDVIR LCDEYERIIR DAIIKGFIEI NGMRLELTKT
     DDIETLGKLI FGKIDKVDLD KTLVDSYRYL LIVMKAALGL NTFHSDKYFV VPSILDQYQT
     ALRDPVFYML QKRIIDLVHL FKLRLPSYTK EDLYFPGVKI DNVVVDKLVT YFDDYLMDMT
     NAVYLTEDEI KKTKSDMVFM VRKRRLNHQP FKVTLDILSD KSVDCVVRVF LGPKKDNLNR
     LIDINRNRLN FVELDTFLYK LNTGKNTIVR NSYDMHNLVK DRMMTRDFMK KVESITDMRD
     LMIKDLRNYH TGFPTRLLLP KGFVGGMHMM LYVIVTPLRL VDNVDINILD INRKDLMRDF
     RSTVLLDKMP LGFPFDRRID VGNFFTPNMK FVEVTIFHKR MTCDMKTRWN RWVLKDYDMV
     DRTRIESDSY FVDTDLDMKV NRNVNLIDV