ID   BKDR_PSEAE              Reviewed;         153 AA.
AC   Q9I1M3;
DT   15-MAY-2007, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   03-AUG-2022, entry version 118.
DE   RecName: Full=Bkd operon transcriptional regulator;
GN   Name=bkdR; OrderedLocusNames=PA2246;
OS   Pseudomonas aeruginosa (strain ATCC 15692 / DSM 22644 / CIP 104116 / JCM
OS   14847 / LMG 12228 / 1C / PRS 101 / PAO1).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pseudomonadales;
OC   Pseudomonadaceae; Pseudomonas.
OX   NCBI_TaxID=208964;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 15692 / DSM 22644 / CIP 104116 / JCM 14847 / LMG 12228 / 1C /
RC   PRS 101 / PAO1;
RX   PubMed=10984043; DOI=10.1038/35023079;
RA   Stover C.K., Pham X.-Q.T., Erwin A.L., Mizoguchi S.D., Warrener P.,
RA   Hickey M.J., Brinkman F.S.L., Hufnagle W.O., Kowalik D.J., Lagrou M.,
RA   Garber R.L., Goltry L., Tolentino E., Westbrock-Wadman S., Yuan Y.,
RA   Brody L.L., Coulter S.N., Folger K.R., Kas A., Larbig K., Lim R.M.,
RA   Smith K.A., Spencer D.H., Wong G.K.-S., Wu Z., Paulsen I.T., Reizer J.,
RA   Saier M.H. Jr., Hancock R.E.W., Lory S., Olson M.V.;
RT   "Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic
RT   pathogen.";
RL   Nature 406:959-964(2000).
CC   -!- FUNCTION: Positive regulator of the bkd operon for branched-chain keto
CC       acid dehydrogenase complex. {ECO:0000250}.
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DR   EMBL; AE004091; AAG05634.1; -; Genomic_DNA.
DR   PIR; B83365; B83365.
DR   RefSeq; NP_250936.1; NC_002516.2.
DR   RefSeq; WP_003089245.1; NZ_QZGE01000014.1.
DR   AlphaFoldDB; Q9I1M3; -.
DR   SMR; Q9I1M3; -.
DR   STRING; 287.DR97_6304; -.
DR   PaxDb; Q9I1M3; -.
DR   PRIDE; Q9I1M3; -.
DR   EnsemblBacteria; AAG05634; AAG05634; PA2246.
DR   GeneID; 879548; -.
DR   KEGG; pae:PA2246; -.
DR   PATRIC; fig|208964.12.peg.2346; -.
DR   PseudoCAP; PA2246; -.
DR   HOGENOM; CLU_091233_0_3_6; -.
DR   InParanoid; Q9I1M3; -.
DR   OMA; TAFILME; -.
DR   PhylomeDB; Q9I1M3; -.
DR   BioCyc; PAER208964:G1FZ6-2285-MON; -.
DR   Proteomes; UP000002438; Chromosome.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0043565; F:sequence-specific DNA binding; IBA:GO_Central.
DR   GO; GO:0006355; P:regulation of transcription, DNA-templated; IEA:UniProt.
DR   GO; GO:0043200; P:response to amino acid; IBA:GO_Central.
DR   CDD; cd00090; HTH_ARSR; 1.
DR   Gene3D; 1.10.10.10; -; 1.
DR   InterPro; IPR011991; ArsR-like_HTH.
DR   InterPro; IPR000485; AsnC-type_HTH_dom.
DR   InterPro; IPR011008; Dimeric_a/b-barrel.
DR   InterPro; IPR019888; Tscrpt_reg_AsnC-like.
DR   InterPro; IPR019887; Tscrpt_reg_AsnC/Lrp_C.
DR   InterPro; IPR036388; WH-like_DNA-bd_sf.
DR   InterPro; IPR036390; WH_DNA-bd_sf.
DR   Pfam; PF01037; AsnC_trans_reg; 1.
DR   PRINTS; PR00033; HTHASNC.
DR   SMART; SM00344; HTH_ASNC; 1.
DR   SUPFAM; SSF46785; SSF46785; 1.
DR   SUPFAM; SSF54909; SSF54909; 1.
DR   PROSITE; PS50956; HTH_ASNC_2; 1.
PE   3: Inferred from homology;
KW   Activator; DNA-binding; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..153
FT                   /note="Bkd operon transcriptional regulator"
FT                   /id="PRO_0000287776"
FT   DOMAIN          4..65
FT                   /note="HTH asnC-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00319"
FT   DNA_BIND        23..42
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00319"
SQ   SEQUENCE   153 AA;  17203 MW;  5BBA7D42C800387B CRC64;
     MAELDRIDLK ILRALADDGR LSWRDLAQKV GLSLTPTLRR VRRLEEEHYI QGYFARLDEE
     RLSGAMSVFV SVSLEKQTGD YLARFEERIV DAPQVMSCFQ MTGDADYMLR VVVKDLAAYQ
     AFLTNTLTCI PGVAGIKSAF ALKSVMLRSA PPL