BL1S1_KLULA
ID BL1S1_KLULA Reviewed; 104 AA.
AC Q6CWM9;
DT 28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT 16-AUG-2004, sequence version 1.
DT 25-MAY-2022, entry version 69.
DE RecName: Full=Biogenesis of lysosome-related organelles complex 1 subunit BLS1;
DE Short=BLOC-1 subunit BLS1;
DE AltName: Full=BLOS1-homolog;
GN Name=BLS1; OrderedLocusNames=KLLA0B02871g;
OS Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX NCBI_TaxID=284590;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX PubMed=15229592; DOI=10.1038/nature02579;
RA Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA Weissenbach J., Wincker P., Souciet J.-L.;
RT "Genome evolution in yeasts.";
RL Nature 430:35-44(2004).
CC -!- FUNCTION: Component of the biogenesis of lysosome-related organelles
CC complex-1 (BLOC-1), a complex involved in endosomal cargo sorting.
CC {ECO:0000250}.
CC -!- SUBUNIT: Component of the biogenesis of lysosome-related organelles
CC complex-1 (BLOC-1). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Endosome {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the BLOC1S1 family. {ECO:0000305}.
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DR EMBL; CR382122; CAH02053.1; -; Genomic_DNA.
DR RefSeq; XP_451660.1; XM_451660.1.
DR AlphaFoldDB; Q6CWM9; -.
DR SMR; Q6CWM9; -.
DR STRING; 28985.XP_451660.1; -.
DR EnsemblFungi; CAH02053; CAH02053; KLLA0_B02871g.
DR GeneID; 2896912; -.
DR KEGG; kla:KLLA0_B02871g; -.
DR eggNOG; ENOG502S787; Eukaryota.
DR HOGENOM; CLU_150164_0_0_1; -.
DR InParanoid; Q6CWM9; -.
DR OMA; IEANHAY; -.
DR Proteomes; UP000000598; Chromosome B.
DR GO; GO:0031083; C:BLOC-1 complex; IEA:EnsemblFungi.
DR GO; GO:0005768; C:endosome; IEA:UniProtKB-SubCell.
DR GO; GO:0007032; P:endosome organization; IEA:EnsemblFungi.
DR GO; GO:0032880; P:regulation of protein localization; IEA:EnsemblFungi.
PE 3: Inferred from homology;
KW Endosome; Reference proteome; Transport.
FT CHAIN 1..104
FT /note="Biogenesis of lysosome-related organelles complex 1
FT subunit BLS1"
FT /id="PRO_0000410630"
SQ SEQUENCE 104 AA; 12052 MW; 093C9A26DAA234C4 CRC64;
MMSNERTLLN QLIKSKTDTV GSEILKEIEG NDEYIKDVQL KKLKELHDKK FKEKGVTPLI
RLYEKYNACA LNDGDLQNWA ELIDRDIRIL EGTIKILEDE SNEG