BL1S1_YEAS7
ID BL1S1_YEAS7 Reviewed; 122 AA.
AC A7A1T1;
DT 28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT 28-JUN-2011, sequence version 2.
DT 25-MAY-2022, entry version 32.
DE RecName: Full=Biogenesis of lysosome-related organelles complex 1 subunit BLS1;
DE Short=BLOC-1 subunit BLS1;
DE AltName: Full=BLOS1-homolog;
GN Name=BLS1; ORFNames=SCY_3959;
OS Saccharomyces cerevisiae (strain YJM789) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=307796;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YJM789;
RX PubMed=17652520; DOI=10.1073/pnas.0701291104;
RA Wei W., McCusker J.H., Hyman R.W., Jones T., Ning Y., Cao Z., Gu Z.,
RA Bruno D., Miranda M., Nguyen M., Wilhelmy J., Komp C., Tamse R., Wang X.,
RA Jia P., Luedi P., Oefner P.J., David L., Dietrich F.S., Li Y., Davis R.W.,
RA Steinmetz L.M.;
RT "Genome sequencing and comparative analysis of Saccharomyces cerevisiae
RT strain YJM789.";
RL Proc. Natl. Acad. Sci. U.S.A. 104:12825-12830(2007).
CC -!- FUNCTION: Component of the biogenesis of lysosome-related organelles
CC complex-1 (BLOC-1), a complex involved in endosomal cargo sorting.
CC {ECO:0000250}.
CC -!- SUBUNIT: Component of the biogenesis of lysosome-related organelles
CC complex-1 (BLOC-1) composed of at least BLI1, BLS1, CNL1, KXD1, SNN1
CC and VAB2. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Endosome {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the BLOC1S1 family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=EDN59309.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AAFW02000171; EDN59309.1; ALT_INIT; Genomic_DNA.
DR AlphaFoldDB; A7A1T1; -.
DR SMR; A7A1T1; -.
DR EnsemblFungi; EDN59309; EDN59309; SCY_3959.
DR HOGENOM; CLU_150164_0_0_1; -.
DR Proteomes; UP000007060; Unassembled WGS sequence.
DR GO; GO:0005768; C:endosome; IEA:UniProtKB-SubCell.
PE 3: Inferred from homology;
KW Endosome; Phosphoprotein; Transport.
FT CHAIN 1..122
FT /note="Biogenesis of lysosome-related organelles complex 1
FT subunit BLS1"
FT /id="PRO_0000410634"
FT MOD_RES 33
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q06071"
SQ SEQUENCE 122 AA; 14548 MW; 0B3BEA4E33149E39 CRC64;
MFLTFSMCVN WIIVKMPNRS EELDRLLDKI INSPHRTEAS KTLQEIENNQ SYILNVQLKK
LLRLHDDSFK NKCVSPINYM LEKYTPYMGH TEALQKEAEL VDRDLRIIEM TYQLIKKNRN
SK