ID   SYGB_ANADE              Reviewed;         701 AA.
AC   Q2IQJ5;
DT   28-JUL-2009, integrated into UniProtKB/Swiss-Prot.
DT   07-MAR-2006, sequence version 1.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=Glycine--tRNA ligase beta subunit {ECO:0000255|HAMAP-Rule:MF_00255};
DE            EC=6.1.1.14 {ECO:0000255|HAMAP-Rule:MF_00255};
DE   AltName: Full=Glycyl-tRNA synthetase beta subunit {ECO:0000255|HAMAP-Rule:MF_00255};
DE            Short=GlyRS {ECO:0000255|HAMAP-Rule:MF_00255};
GN   Name=glyS {ECO:0000255|HAMAP-Rule:MF_00255}; OrderedLocusNames=Adeh_1306;
OS   Anaeromyxobacter dehalogenans (strain 2CP-C).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Myxococcales;
OC   Cystobacterineae; Anaeromyxobacteraceae; Anaeromyxobacter.
OX   NCBI_TaxID=290397;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=2CP-C;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Brettin T., Bruce D., Han C., Tapia R.,
RA   Gilna P., Kiss H., Schmutz J., Larimer F., Land M., Kyrpides N.,
RA   Anderson I., Sanford R.A., Ritalahti K.M., Thomas H.S., Kirby J.R.,
RA   Zhulin I.B., Loeffler F.E., Richardson P.;
RT   "Complete sequence of Anaeromyxobacter dehalogenans 2CP-C.";
RL   Submitted (JAN-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-
CC         tRNA(Gly); Xref=Rhea:RHEA:16013, Rhea:RHEA-COMP:9664, Rhea:RHEA-
CC         COMP:9683, ChEBI:CHEBI:30616, ChEBI:CHEBI:33019, ChEBI:CHEBI:57305,
CC         ChEBI:CHEBI:78442, ChEBI:CHEBI:78522, ChEBI:CHEBI:456215;
CC         EC=6.1.1.14; Evidence={ECO:0000255|HAMAP-Rule:MF_00255};
CC   -!- SUBUNIT: Tetramer of two alpha and two beta subunits.
CC       {ECO:0000255|HAMAP-Rule:MF_00255}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00255}.
CC   -!- SIMILARITY: Belongs to the class-II aminoacyl-tRNA synthetase family.
CC       {ECO:0000255|HAMAP-Rule:MF_00255}.
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DR   EMBL; CP000251; ABC81080.1; -; Genomic_DNA.
DR   RefSeq; WP_011420363.1; NC_007760.1.
DR   AlphaFoldDB; Q2IQJ5; -.
DR   SMR; Q2IQJ5; -.
DR   STRING; 290397.Adeh_1306; -.
DR   EnsemblBacteria; ABC81080; ABC81080; Adeh_1306.
DR   KEGG; ade:Adeh_1306; -.
DR   eggNOG; COG0751; Bacteria.
DR   HOGENOM; CLU_007220_2_1_7; -.
DR   OMA; LPIPKRM; -.
DR   Proteomes; UP000001935; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004814; F:arginine-tRNA ligase activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0004820; F:glycine-tRNA ligase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006420; P:arginyl-tRNA aminoacylation; IEA:InterPro.
DR   GO; GO:0006426; P:glycyl-tRNA aminoacylation; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00255; Gly_tRNA_synth_beta; 1.
DR   InterPro; IPR008909; DALR_anticod-bd.
DR   InterPro; IPR015944; Gly-tRNA-synth_bsu.
DR   InterPro; IPR006194; Gly-tRNA-synth_heterodimer.
DR   PANTHER; PTHR30075; PTHR30075; 1.
DR   Pfam; PF05746; DALR_1; 1.
DR   Pfam; PF02092; tRNA_synt_2f; 1.
DR   PRINTS; PR01045; TRNASYNTHGB.
DR   SMART; SM00836; DALR_1; 1.
DR   TIGRFAMs; TIGR00211; glyS; 1.
DR   PROSITE; PS50861; AA_TRNA_LIGASE_II_GLYAB; 1.
PE   3: Inferred from homology;
KW   Aminoacyl-tRNA synthetase; ATP-binding; Cytoplasm; Ligase;
KW   Nucleotide-binding; Protein biosynthesis; Reference proteome.
FT   CHAIN           1..701
FT                   /note="Glycine--tRNA ligase beta subunit"
FT                   /id="PRO_1000197167"
SQ   SEQUENCE   701 AA;  75799 MW;  02A4676EF5A6D8C1 CRC64;
     MADLLFEIGA EEIPAGFVPG ALRQLEDDLA KALADARLAH GEVRAVGTPR RLAVWARDVA
     PKQTDARTEA FGPPVAQAYD AEGKPTPAAT GFARSQGVEV SALVRAQTPK GERVAVTKVE
     KGRKAEQVLP ALLERLVAGL RFRKAMRSRF DEVTFARPVR WMVALLGGRP LKVRHGEVAS
     GKVTYGHRFL APKAIALKGT PDDYLAKLRR AHVLADPEER RAALLAELAR AGKEAGGKVR
     DDPALVEQVL YLVEEPSAVV GEFERSNLEL PPEVVISEMR NHQRYFAVVD GKGRLKNRFV
     AVSATRVKDP AVARHGYERV LRARLADARF FFEEDRKRKL HERIEDLGRR TFQAKLGSEL
     DRAQRIGAVA SGLARALGKD ALVADLLEAS RLAKVDLNTG MVGEFPELQG TMGAHYARLE
     GLKPEIADAI EDHYKPIGAA EEMPRSDLGA LVAVADRLHS LVGIIGVGEK ATGAADPFGL
     RRAAIGILRI VIARGYHLSL ATAVEQTLDA LAGVKLAAGR ALVAEQVLDF LRGRVRAAWT
     ERFDADLVEA VLAAGSDDVV DARRRLEALA EAKARPDFGS LAVAFKRVAN IQEKAGGPGA
     AAVDPALLRD PAEQDLLAAL EKVEQEVGAR RAARDYPAVL RTVATLEPAV ARFFDDVLVM
     AEDPALRANR LGLMRRVGAL FSDLADFRKI QAEAPAQARA G