ID   SYGB_DESVH              Reviewed;         696 AA.
AC   Q72AU3;
DT   14-APR-2009, integrated into UniProtKB/Swiss-Prot.
DT   05-JUL-2004, sequence version 1.
DT   03-AUG-2022, entry version 113.
DE   RecName: Full=Glycine--tRNA ligase beta subunit {ECO:0000255|HAMAP-Rule:MF_00255};
DE            EC=6.1.1.14 {ECO:0000255|HAMAP-Rule:MF_00255};
DE   AltName: Full=Glycyl-tRNA synthetase beta subunit {ECO:0000255|HAMAP-Rule:MF_00255};
DE            Short=GlyRS {ECO:0000255|HAMAP-Rule:MF_00255};
GN   Name=glyS {ECO:0000255|HAMAP-Rule:MF_00255}; OrderedLocusNames=DVU_1897;
OS   Desulfovibrio vulgaris (strain ATCC 29579 / DSM 644 / NCIMB 8303 / VKM
OS   B-1760 / Hildenborough).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Desulfovibrionales;
OC   Desulfovibrionaceae; Desulfovibrio.
OX   NCBI_TaxID=882;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 29579 / DSM 644 / NCIMB 8303 / VKM B-1760 / Hildenborough;
RX   PubMed=15077118; DOI=10.1038/nbt959;
RA   Heidelberg J.F., Seshadri R., Haveman S.A., Hemme C.L., Paulsen I.T.,
RA   Kolonay J.F., Eisen J.A., Ward N.L., Methe B.A., Brinkac L.M.,
RA   Daugherty S.C., DeBoy R.T., Dodson R.J., Durkin A.S., Madupu R.,
RA   Nelson W.C., Sullivan S.A., Fouts D.E., Haft D.H., Selengut J.,
RA   Peterson J.D., Davidsen T.M., Zafar N., Zhou L., Radune D., Dimitrov G.,
RA   Hance M., Tran K., Khouri H.M., Gill J., Utterback T.R., Feldblyum T.V.,
RA   Wall J.D., Voordouw G., Fraser C.M.;
RT   "The genome sequence of the anaerobic, sulfate-reducing bacterium
RT   Desulfovibrio vulgaris Hildenborough.";
RL   Nat. Biotechnol. 22:554-559(2004).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-
CC         tRNA(Gly); Xref=Rhea:RHEA:16013, Rhea:RHEA-COMP:9664, Rhea:RHEA-
CC         COMP:9683, ChEBI:CHEBI:30616, ChEBI:CHEBI:33019, ChEBI:CHEBI:57305,
CC         ChEBI:CHEBI:78442, ChEBI:CHEBI:78522, ChEBI:CHEBI:456215;
CC         EC=6.1.1.14; Evidence={ECO:0000255|HAMAP-Rule:MF_00255};
CC   -!- SUBUNIT: Tetramer of two alpha and two beta subunits.
CC       {ECO:0000255|HAMAP-Rule:MF_00255}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00255}.
CC   -!- SIMILARITY: Belongs to the class-II aminoacyl-tRNA synthetase family.
CC       {ECO:0000255|HAMAP-Rule:MF_00255}.
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DR   EMBL; AE017285; AAS96373.1; -; Genomic_DNA.
DR   RefSeq; WP_010939183.1; NC_002937.3.
DR   RefSeq; YP_011114.1; NC_002937.3.
DR   AlphaFoldDB; Q72AU3; -.
DR   SMR; Q72AU3; -.
DR   IntAct; Q72AU3; 1.
DR   STRING; 882.DVU_1897; -.
DR   PaxDb; Q72AU3; -.
DR   EnsemblBacteria; AAS96373; AAS96373; DVU_1897.
DR   KEGG; dvu:DVU_1897; -.
DR   PATRIC; fig|882.5.peg.1740; -.
DR   eggNOG; COG0751; Bacteria.
DR   HOGENOM; CLU_007220_2_2_7; -.
DR   OMA; LPIPKRM; -.
DR   PhylomeDB; Q72AU3; -.
DR   Proteomes; UP000002194; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0004820; F:glycine-tRNA ligase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006426; P:glycyl-tRNA aminoacylation; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00255; Gly_tRNA_synth_beta; 1.
DR   InterPro; IPR015944; Gly-tRNA-synth_bsu.
DR   InterPro; IPR006194; Gly-tRNA-synth_heterodimer.
DR   PANTHER; PTHR30075; PTHR30075; 1.
DR   Pfam; PF02092; tRNA_synt_2f; 1.
DR   PRINTS; PR01045; TRNASYNTHGB.
DR   TIGRFAMs; TIGR00211; glyS; 1.
DR   PROSITE; PS50861; AA_TRNA_LIGASE_II_GLYAB; 1.
PE   3: Inferred from homology;
KW   Aminoacyl-tRNA synthetase; ATP-binding; Cytoplasm; Ligase;
KW   Nucleotide-binding; Protein biosynthesis; Reference proteome.
FT   CHAIN           1..696
FT                   /note="Glycine--tRNA ligase beta subunit"
FT                   /id="PRO_1000197179"
SQ   SEQUENCE   696 AA;  75402 MW;  416C7EC9BF427E32 CRC64;
     MSQFVLEIGT EELPARFLPA LERELAERFT RALADAGIEC DPVRVMSTPR RAVVRMDAVN
     PVQSESEEVV TGPPARIAFT PEGGLTKAAE GFARTQGVEV ADIFRLTTDK GEYIAVRKHM
     GGARSIDLLR DICPAIIGAL PFPKRMRWGS GDFTYARPMR WLLALFDESV VDFEVGGVRS
     GNITYGHRIH GAGPLTVARA GDYERVIREQ GGVTPVGEER RNAVVKGGNA LAVAAGGKVI
     WKDSLLDEVQ GLVEHPVPCL GNIDPSFLEL PREVLLTSME SHQKSFGVED AEGRLMPHFL
     TVLNLTPLDG DLVRKGWERV LRARLEDARF FWKTDLASSF DAWLASLDNV IFLGPLGSMG
     DKTRRLEQLC AWLAAEVGFD DATAAARAGR LSKGDLVSGM VGEFDTLQGI MGGIYARRMG
     EAEAVAAAIA EQYLPAGPDS PVPSSMCGAL LSIADKADTL AGCFGLGMIP TGAADPYALR
     RCVLGIARII LEHGLQLDVR GLFAKAFALY GERAWKLAPE DALVKLDEFF MARLRNLFIA
     NGYETLLVEA VLAAGCDDVR SAGARLEALA AFSRRDDFAS AVLTFKRAAN IIRKQGGDSD
     VALDGAWKAD LLVEDAERQL AASLEAMFPR FDGLWAEGDY PALFGLLGEL RPVVDGFFEG
     VMVMSDDAAL RTNRLNLLQA LVGRLSRLAD FGALQM