BL1S4_ASHGO
ID BL1S4_ASHGO Reviewed; 129 AA.
AC Q756L2;
DT 28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 03-AUG-2022, entry version 81.
DE RecName: Full=Biogenesis of lysosome-related organelles complex 1 subunit CNL1;
DE Short=BLOC-1 subunit CNL1;
DE AltName: Full=CNO-like protein 1;
GN Name=CLN1; OrderedLocusNames=AER242C; ORFNames=AGOS_AER242C;
OS Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS (Yeast) (Eremothecium gossypii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX NCBI_TaxID=284811;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX PubMed=15001715; DOI=10.1126/science.1095781;
RA Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA Gaffney T.D., Philippsen P.;
RT "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT cerevisiae genome.";
RL Science 304:304-307(2004).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX PubMed=23749448; DOI=10.1534/g3.112.002881;
RA Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT loci, numerous translocations, lack of transposons, and distinct gene
RT duplications.";
RL G3 (Bethesda) 3:1225-1239(2013).
CC -!- FUNCTION: Component of the biogenesis of lysosome-related organelles
CC complex-1 (BLOC-1), a complex that is involved in endosomal cargo
CC sorting. {ECO:0000250}.
CC -!- SUBUNIT: Component of the biogenesis of lysosome-related organelles
CC complex-1 (BLOC-1). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Note=Punctate pattern.
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the BLOC1S4 family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AE016818; AAS52923.1; -; Genomic_DNA.
DR RefSeq; NP_985099.1; NM_210453.1.
DR AlphaFoldDB; Q756L2; -.
DR SMR; Q756L2; -.
DR STRING; 33169.AAS52923; -.
DR PRIDE; Q756L2; -.
DR EnsemblFungi; AAS52923; AAS52923; AGOS_AER242C.
DR GeneID; 4621309; -.
DR KEGG; ago:AGOS_AER242C; -.
DR eggNOG; ENOG502S4DQ; Eukaryota.
DR HOGENOM; CLU_141728_1_0_1; -.
DR InParanoid; Q756L2; -.
DR OMA; HFDMLDQ; -.
DR Proteomes; UP000000591; Chromosome V.
DR GO; GO:0031083; C:BLOC-1 complex; IBA:GO_Central.
DR GO; GO:0005768; C:endosome; IEA:EnsemblFungi.
DR GO; GO:0007032; P:endosome organization; IBA:GO_Central.
DR GO; GO:0032880; P:regulation of protein localization; IEA:EnsemblFungi.
DR InterPro; IPR034455; CNL1.
DR PANTHER; PTHR39145; PTHR39145; 1.
PE 3: Inferred from homology;
KW Cytoplasm; Reference proteome; Transport.
FT CHAIN 1..129
FT /note="Biogenesis of lysosome-related organelles complex 1
FT subunit CNL1"
FT /id="PRO_0000410641"
SQ SEQUENCE 129 AA; 14880 MW; B7CF688B0B2CED4A CRC64;
MVAEAGASIQ AEDVNNDPFR VDQLILDYDY MLYRIKDHVA SIHLATTELC RKQNQLVCTG
IVEEIIDSNI KNVRELLTKC KELETYFEQL HAIDGIVSTF HERMDEIVKQ YRDIKVHTDS
ASRDHVATK