ID   BL1S4_CAEEL             Reviewed;         106 AA.
AC   Q22756;
DT   28-NOV-2012, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1996, sequence version 1.
DT   03-AUG-2022, entry version 100.
DE   RecName: Full=Biogenesis of lysosome-related organelles complex 1 subunit 4;
DE            Short=BLOC-1 subunit 4;
DE   AltName: Full=Protein cappuccino homolog;
GN   Name=blos-4; ORFNames=T24H7.4;
OS   Caenorhabditis elegans.
OC   Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC   Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC   Caenorhabditis.
OX   NCBI_TaxID=6239;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Bristol N2;
RX   PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG   The C. elegans sequencing consortium;
RT   "Genome sequence of the nematode C. elegans: a platform for investigating
RT   biology.";
RL   Science 282:2012-2018(1998).
RN   [2]
RP   IDENTIFICATION IN THE BLOC-1 COMPLEX, FUNCTION, AND INTERACTION WITH GLO-2.
RX   PubMed=22916203; DOI=10.1371/journal.pone.0043043;
RA   Hermann G.J., Scavarda E., Weis A.M., Saxton D.S., Thomas L.L., Salesky R.,
RA   Somhegyi H., Curtin T.P., Barrett A., Foster O.K., Vine A., Erlich K.,
RA   Kwan E., Rabbitts B.M., Warren K.;
RT   "C. elegans BLOC-1 Functions in Trafficking to Lysosome-Related Gut
RT   Granules.";
RL   PLoS ONE 7:E43043-E43043(2012).
CC   -!- FUNCTION: Component of the biogenesis of lysosome-related organelles
CC       complex-1 (BLOC-1) involved in gut granule biogenesis.
CC       {ECO:0000269|PubMed:22916203}.
CC   -!- SUBUNIT: Component of the biogenesis of lysosome-related organelles
CC       complex-1 (BLOC-1) composed at least of blos-1, blos-2, blos-4, dsbn-1,
CC       glo-2, mutd-1 and snpn-1. Interacts with glo-2.
CC       {ECO:0000269|PubMed:22916203}.
CC   -!- SIMILARITY: Belongs to the BLOC1S4 family. {ECO:0000305}.
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DR   EMBL; FO080720; CCD66145.1; -; Genomic_DNA.
DR   PIR; E88175; E88175.
DR   RefSeq; NP_495247.1; NM_062846.1.
DR   AlphaFoldDB; Q22756; -.
DR   SMR; Q22756; -.
DR   BioGRID; 53522; 8.
DR   ComplexPortal; CPX-479; Bloc-1 complex.
DR   DIP; DIP-25653N; -.
DR   IntAct; Q22756; 5.
DR   STRING; 6239.T24H7.4.2; -.
DR   EPD; Q22756; -.
DR   PaxDb; Q22756; -.
DR   PeptideAtlas; Q22756; -.
DR   EnsemblMetazoa; T24H7.4.1; T24H7.4.1; WBGene00020783.
DR   GeneID; 188869; -.
DR   KEGG; cel:CELE_T24H7.4; -.
DR   UCSC; T24H7.4; c. elegans.
DR   CTD; 188869; -.
DR   WormBase; T24H7.4; CE02886; WBGene00020783; blos-4.
DR   eggNOG; ENOG502TIEA; Eukaryota.
DR   HOGENOM; CLU_2252437_0_0_1; -.
DR   InParanoid; Q22756; -.
DR   OMA; YNVVDRQ; -.
DR   OrthoDB; 1586423at2759; -.
DR   PRO; PR:Q22756; -.
DR   Proteomes; UP000001940; Chromosome II.
DR   Bgee; WBGene00020783; Expressed in germ line (C elegans) and 4 other tissues.
DR   GO; GO:0031082; C:BLOC complex; IC:ComplexPortal.
DR   GO; GO:0031083; C:BLOC-1 complex; TAS:UniProtKB.
DR   GO; GO:0016197; P:endosomal transport; IMP:UniProtKB.
DR   GO; GO:1904757; P:positive regulation of gut granule assembly; IC:ComplexPortal.
PE   1: Evidence at protein level;
KW   Coiled coil; Reference proteome.
FT   CHAIN           1..106
FT                   /note="Biogenesis of lysosome-related organelles complex 1
FT                   subunit 4"
FT                   /id="PRO_0000420195"
FT   COILED          53..106
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   106 AA;  11826 MW;  2C9E905127E5B1D9 CRC64;
     MTGVDDISSN VHKLVGVTAG MNTAASTGPM NLVLDKCSVV LEELRTIQIL TETHSEGLSE
     QLKMTEKNIL EMENLFDQID QLCLFVQKAK SDLDKLEKLY NVVDRQ