ID   SYGB_GEOMG              Reviewed;         686 AA.
AC   Q39RG5;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   22-NOV-2005, sequence version 1.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=Glycine--tRNA ligase beta subunit {ECO:0000255|HAMAP-Rule:MF_00255};
DE            EC=6.1.1.14 {ECO:0000255|HAMAP-Rule:MF_00255};
DE   AltName: Full=Glycyl-tRNA synthetase beta subunit {ECO:0000255|HAMAP-Rule:MF_00255};
DE            Short=GlyRS {ECO:0000255|HAMAP-Rule:MF_00255};
GN   Name=glyS {ECO:0000255|HAMAP-Rule:MF_00255}; OrderedLocusNames=Gmet_2941;
OS   Geobacter metallireducens (strain ATCC 53774 / DSM 7210 / GS-15).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Desulfuromonadales;
OC   Geobacteraceae; Geobacter.
OX   NCBI_TaxID=269799;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 53774 / DSM 7210 / GS-15;
RG   US DOE Joint Genome Institute;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Di Bartolo G., Chain P., Schmutz J.,
RA   Larimer F., Land M., Kyrpides N., Ivanova N., Richardson P.;
RT   "Complete sequence of Geobacter metallireducens GS-15.";
RL   Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-
CC         tRNA(Gly); Xref=Rhea:RHEA:16013, Rhea:RHEA-COMP:9664, Rhea:RHEA-
CC         COMP:9683, ChEBI:CHEBI:30616, ChEBI:CHEBI:33019, ChEBI:CHEBI:57305,
CC         ChEBI:CHEBI:78442, ChEBI:CHEBI:78522, ChEBI:CHEBI:456215;
CC         EC=6.1.1.14; Evidence={ECO:0000255|HAMAP-Rule:MF_00255};
CC   -!- SUBUNIT: Tetramer of two alpha and two beta subunits.
CC       {ECO:0000255|HAMAP-Rule:MF_00255}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00255}.
CC   -!- SIMILARITY: Belongs to the class-II aminoacyl-tRNA synthetase family.
CC       {ECO:0000255|HAMAP-Rule:MF_00255}.
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DR   EMBL; CP000148; ABB33159.1; -; Genomic_DNA.
DR   RefSeq; WP_004512877.1; NC_007517.1.
DR   AlphaFoldDB; Q39RG5; -.
DR   SMR; Q39RG5; -.
DR   STRING; 269799.Gmet_2941; -.
DR   PRIDE; Q39RG5; -.
DR   EnsemblBacteria; ABB33159; ABB33159; Gmet_2941.
DR   KEGG; gme:Gmet_2941; -.
DR   eggNOG; COG0751; Bacteria.
DR   HOGENOM; CLU_007220_2_2_7; -.
DR   OMA; LPIPKRM; -.
DR   OrthoDB; 213210at2; -.
DR   Proteomes; UP000007073; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0004820; F:glycine-tRNA ligase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006426; P:glycyl-tRNA aminoacylation; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00255; Gly_tRNA_synth_beta; 1.
DR   InterPro; IPR015944; Gly-tRNA-synth_bsu.
DR   InterPro; IPR006194; Gly-tRNA-synth_heterodimer.
DR   PANTHER; PTHR30075; PTHR30075; 1.
DR   Pfam; PF02092; tRNA_synt_2f; 1.
DR   PRINTS; PR01045; TRNASYNTHGB.
DR   TIGRFAMs; TIGR00211; glyS; 1.
DR   PROSITE; PS50861; AA_TRNA_LIGASE_II_GLYAB; 1.
PE   3: Inferred from homology;
KW   Aminoacyl-tRNA synthetase; ATP-binding; Cytoplasm; Ligase;
KW   Nucleotide-binding; Protein biosynthesis; Reference proteome.
FT   CHAIN           1..686
FT                   /note="Glycine--tRNA ligase beta subunit"
FT                   /id="PRO_1000006361"
SQ   SEQUENCE   686 AA;  74759 MW;  80F12E8A87A3CF78 CRC64;
     MKELFLEIGT EEIPAGFIPK AMADMEALLA KELENARISF DDIRTLGTPR RLALTVKGLP
     TVQPDAEITA MGPARNVAFD AEGKPTRAAE GFARGQGVDV ASLTLVATEK GEYVAAVRKE
     SGRPVPELLA EILPRLVANI PFRKSMRWGA LDVRFARPIH WIVALFDGVV VPFTFGNIES
     GTISRGHRFM ANQPFPVRDF AHYLEECERH FVIPDPERRQ EIIRREIHRV AKAAGGHLLP
     DEGLLEEVSF LCEYPSAVHG TFSAEFLKVP REVLITSMRS HQRYFSIVDD AGKLMPGFIT
     INNTLTEDPT VVVKGNERVL RARLSDARFF FEEDQKVKLE TRVESLKNVV YQQKLGTSFE
     KMERFRALAE GLADLLNPAV KVKVSQAAFL CKADLVSGMV GEFPEVQGIM GREYALIEGE
     DAEVAAAIAE HYLPTQAGGE LPASDIGAFV SMADKLDTIC GCFGVGLIPT GSADPYALRR
     SALGIINIIL DKGYRLSLEE QVDKALGLLA AKLTRPAVDV KADVLEFFRG RFVNLMADRH
     ASDAVDAAVA AGCADLVDAA ARIAALSEFR SHPDFEPLAV AFKRVGNIVK EGVDAPVDTA
     LFQDAAEGLL NDAVQGVAVS VREKIATGAY LEALTEIAAL RGPVDTFFDK VMVMAEDERV
     RTNRLALLTG IARMLGAIAD FAKIAA