ID   BL1S4_KLULA             Reviewed;         124 AA.
AC   Q6CMB6;
DT   28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT   16-AUG-2004, sequence version 1.
DT   25-MAY-2022, entry version 76.
DE   RecName: Full=Biogenesis of lysosome-related organelles complex 1 subunit CNL1;
DE            Short=BLOC-1 subunit CNL1;
DE   AltName: Full=CNO-like protein 1;
GN   Name=CLN1; OrderedLocusNames=KLLA0E21495g;
OS   Kluyveromyces lactis (strain ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 /
OS   NRRL Y-1140 / WM37) (Yeast) (Candida sphaerica).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC   Saccharomycetales; Saccharomycetaceae; Kluyveromyces.
OX   NCBI_TaxID=284590;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8585 / CBS 2359 / DSM 70799 / NBRC 1267 / NRRL Y-1140 / WM37;
RX   PubMed=15229592; DOI=10.1038/nature02579;
RA   Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I.,
RA   de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L.,
RA   Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.,
RA   Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J.,
RA   Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E.,
RA   Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C.,
RA   Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M.,
RA   Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S.,
RA   Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F.,
RA   Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M.,
RA   Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M.,
RA   Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C.,
RA   Weissenbach J., Wincker P., Souciet J.-L.;
RT   "Genome evolution in yeasts.";
RL   Nature 430:35-44(2004).
CC   -!- FUNCTION: Component of the biogenesis of lysosome-related organelles
CC       complex-1 (BLOC-1), a complex that is involved in endosomal cargo
CC       sorting. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the biogenesis of lysosome-related organelles
CC       complex-1 (BLOC-1). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Note=Punctate pattern.
CC       {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the BLOC1S4 family. {ECO:0000305}.
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DR   EMBL; CR382125; CAH00010.1; -; Genomic_DNA.
DR   RefSeq; XP_454923.1; XM_454923.1.
DR   AlphaFoldDB; Q6CMB6; -.
DR   STRING; 28985.XP_454923.1; -.
DR   EnsemblFungi; CAH00010; CAH00010; KLLA0_E21495g.
DR   GeneID; 2894629; -.
DR   KEGG; kla:KLLA0_E21495g; -.
DR   eggNOG; ENOG502S4DQ; Eukaryota.
DR   HOGENOM; CLU_141728_1_0_1; -.
DR   InParanoid; Q6CMB6; -.
DR   OMA; HFDMLDQ; -.
DR   Proteomes; UP000000598; Chromosome E.
DR   GO; GO:0031083; C:BLOC-1 complex; IEA:EnsemblFungi.
DR   GO; GO:0005768; C:endosome; IEA:EnsemblFungi.
DR   GO; GO:0007032; P:endosome organization; IEA:EnsemblFungi.
DR   GO; GO:0032880; P:regulation of protein localization; IEA:EnsemblFungi.
DR   InterPro; IPR034455; CNL1.
DR   PANTHER; PTHR39145; PTHR39145; 1.
PE   3: Inferred from homology;
KW   Coiled coil; Cytoplasm; Reference proteome; Transport.
FT   CHAIN           1..124
FT                   /note="Biogenesis of lysosome-related organelles complex 1
FT                   subunit CNL1"
FT                   /id="PRO_0000410643"
FT   REGION          1..20
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          75..98
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   124 AA;  14312 MW;  D4A96D43D2BBE9CB CRC64;
     MMSENITAVE PQENNDVEAD SDPFNIDKLI VDYDYLLYKI QDELESIQLK TLEICQKQNE
     IVEHGIIEEV IDGNIGMAKD LLQKCDDLEK HYDQLDAVEG IVVSFKSRLK GVITQYKKYI
     DTKK