BL1S4_LACTC
ID BL1S4_LACTC Reviewed; 131 AA.
AC C5DJH5;
DT 28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT 28-JUL-2009, sequence version 1.
DT 25-MAY-2022, entry version 48.
DE RecName: Full=Biogenesis of lysosome-related organelles complex 1 subunit CNL1;
DE Short=BLOC-1 subunit CNL1;
DE AltName: Full=CNO-like protein 1;
GN Name=CLN1; OrderedLocusNames=KLTH0F16478g;
OS Lachancea thermotolerans (strain ATCC 56472 / CBS 6340 / NRRL Y-8284)
OS (Yeast) (Kluyveromyces thermotolerans).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Lachancea.
OX NCBI_TaxID=559295;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 56472 / CBS 6340 / NRRL Y-8284;
RX PubMed=19525356; DOI=10.1101/gr.091546.109;
RG The Genolevures Consortium;
RA Souciet J.-L., Dujon B., Gaillardin C., Johnston M., Baret P.V.,
RA Cliften P., Sherman D.J., Weissenbach J., Westhof E., Wincker P., Jubin C.,
RA Poulain J., Barbe V., Segurens B., Artiguenave F., Anthouard V.,
RA Vacherie B., Val M.-E., Fulton R.S., Minx P., Wilson R., Durrens P.,
RA Jean G., Marck C., Martin T., Nikolski M., Rolland T., Seret M.-L.,
RA Casaregola S., Despons L., Fairhead C., Fischer G., Lafontaine I., Leh V.,
RA Lemaire M., de Montigny J., Neuveglise C., Thierry A., Blanc-Lenfle I.,
RA Bleykasten C., Diffels J., Fritsch E., Frangeul L., Goeffon A.,
RA Jauniaux N., Kachouri-Lafond R., Payen C., Potier S., Pribylova L.,
RA Ozanne C., Richard G.-F., Sacerdot C., Straub M.-L., Talla E.;
RT "Comparative genomics of protoploid Saccharomycetaceae.";
RL Genome Res. 19:1696-1709(2009).
CC -!- FUNCTION: Component of the biogenesis of lysosome-related organelles
CC complex-1 (BLOC-1), a complex that is involved in endosomal cargo
CC sorting. {ECO:0000250}.
CC -!- SUBUNIT: Component of the biogenesis of lysosome-related organelles
CC complex-1 (BLOC-1). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Note=Punctate pattern.
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the BLOC1S4 family. {ECO:0000305}.
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DR EMBL; CU928170; CAR24464.1; -; Genomic_DNA.
DR RefSeq; XP_002554901.1; XM_002554855.1.
DR AlphaFoldDB; C5DJH5; -.
DR SMR; C5DJH5; -.
DR STRING; 559295.C5DJH5; -.
DR EnsemblFungi; CAR24464; CAR24464; KLTH0F16478g.
DR GeneID; 8293134; -.
DR KEGG; lth:KLTH0F16478g; -.
DR eggNOG; ENOG502S4DQ; Eukaryota.
DR HOGENOM; CLU_141728_1_0_1; -.
DR InParanoid; C5DJH5; -.
DR OMA; HFDMLDQ; -.
DR OrthoDB; 1564181at2759; -.
DR Proteomes; UP000002036; Chromosome F.
DR GO; GO:0031083; C:BLOC-1 complex; IEA:InterPro.
DR InterPro; IPR034455; CNL1.
DR PANTHER; PTHR39145; PTHR39145; 1.
PE 3: Inferred from homology;
KW Coiled coil; Cytoplasm; Reference proteome; Transport.
FT CHAIN 1..131
FT /note="Biogenesis of lysosome-related organelles complex 1
FT subunit CNL1"
FT /id="PRO_0000410644"
FT REGION 1..29
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 73..101
FT /evidence="ECO:0000255"
SQ SEQUENCE 131 AA; 15183 MW; CB36296D13C4F5A4 CRC64;
MSAPDSNSGH AHDSAQNEGA AEGTRDPFGI DRLSVDYDYL LYRIQDHVTS IQLSTTEICR
QQNQLVEQGI IGDAIDINIE EMRRILQKCE ELETHFDMLD QIDSIVQTFR PRLDDIVREH
RELTRNTERR I