BL1S4_YEAS7
ID BL1S4_YEAS7 Reviewed; 122 AA.
AC A6ZYV6;
DT 28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT 11-SEP-2007, sequence version 1.
DT 25-MAY-2022, entry version 32.
DE RecName: Full=Biogenesis of lysosome-related organelles complex 1 subunit CNL1;
DE Short=BLOC-1 subunit CNL1;
DE AltName: Full=CNO-like protein 1;
GN Name=CLN1; ORFNames=SCY_1244;
OS Saccharomyces cerevisiae (strain YJM789) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=307796;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=YJM789;
RX PubMed=17652520; DOI=10.1073/pnas.0701291104;
RA Wei W., McCusker J.H., Hyman R.W., Jones T., Ning Y., Cao Z., Gu Z.,
RA Bruno D., Miranda M., Nguyen M., Wilhelmy J., Komp C., Tamse R., Wang X.,
RA Jia P., Luedi P., Oefner P.J., David L., Dietrich F.S., Li Y., Davis R.W.,
RA Steinmetz L.M.;
RT "Genome sequencing and comparative analysis of Saccharomyces cerevisiae
RT strain YJM789.";
RL Proc. Natl. Acad. Sci. U.S.A. 104:12825-12830(2007).
CC -!- FUNCTION: Component of the biogenesis of lysosome-related organelles
CC complex-1 (BLOC-1), a complex that is involved in endosomal cargo
CC sorting. {ECO:0000250}.
CC -!- SUBUNIT: Component of the biogenesis of lysosome-related organelles
CC complex-1 (BLOC-1) composed of at least BLI1, BLS1, CNL1, KXD1, SNN1
CC and VAB2. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Note=Punctate pattern.
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the BLOC1S4 family. {ECO:0000305}.
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DR EMBL; AAFW02000145; EDN60686.1; -; Genomic_DNA.
DR AlphaFoldDB; A6ZYV6; -.
DR SMR; A6ZYV6; -.
DR EnsemblFungi; EDN60686; EDN60686; SCY_1244.
DR HOGENOM; CLU_141728_1_0_1; -.
DR Proteomes; UP000007060; Unassembled WGS sequence.
DR GO; GO:0031083; C:BLOC-1 complex; IEA:InterPro.
DR InterPro; IPR034455; CNL1.
DR PANTHER; PTHR39145; PTHR39145; 1.
PE 3: Inferred from homology;
KW Coiled coil; Cytoplasm; Transport.
FT CHAIN 1..122
FT /note="Biogenesis of lysosome-related organelles complex 1
FT subunit CNL1"
FT /id="PRO_0000410648"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 63..95
FT /evidence="ECO:0000255"
SQ SEQUENCE 122 AA; 13939 MW; 060EE9B58CD3388B CRC64;
MQDNSSHSRE SASAGDDPLG IDKLTVDYDY LLYKIRDYVQ SIQLDTTELC KKQNEVMVNG
IIENTIDKNI AKFKELLEKC DTLENHYEML NQLAIITDTF KERIAEAVNN YNSLKKGASK
SK