BL1S4_YEASB
ID BL1S4_YEASB Reviewed; 109 AA.
AC E7Q2L9;
DT 28-JUN-2011, integrated into UniProtKB/Swiss-Prot.
DT 05-APR-2011, sequence version 1.
DT 25-MAY-2022, entry version 32.
DE RecName: Full=Biogenesis of lysosome-related organelles complex 1 subunit CNL1;
DE Short=BLOC-1 subunit CNL1;
DE AltName: Full=CNO-like protein 1;
GN Name=CLN1; ORFNames=FOSTERSB_1043;
OS Saccharomyces cerevisiae (strain FostersB) (Baker's yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Saccharomyces.
OX NCBI_TaxID=764102;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=FostersB;
RX PubMed=21304888; DOI=10.1371/journal.pgen.1001287;
RA Borneman A.R., Desany B.A., Riches D., Affourtit J.P., Forgan A.H.,
RA Pretorius I.S., Egholm M., Chambers P.J.;
RT "Whole-genome comparison reveals novel genetic elements that characterize
RT the genome of industrial strains of Saccharomyces cerevisiae.";
RL PLoS Genet. 7:E1001287-E1001287(2011).
CC -!- FUNCTION: Component of the biogenesis of lysosome-related organelles
CC complex-1 (BLOC-1), a complex that is involved in endosomal cargo
CC sorting. {ECO:0000250}.
CC -!- SUBUNIT: Component of the biogenesis of lysosome-related organelles
CC complex-1 (BLOC-1) composed of at least BLI1, BLS1, CNL1, KXD1, SNN1
CC and VAB2. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000250}. Note=Punctate pattern.
CC {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the BLOC1S4 family. {ECO:0000305}.
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DR EMBL; AEHH01000013; EGA59190.1; -; Genomic_DNA.
DR AlphaFoldDB; E7Q2L9; -.
DR SMR; E7Q2L9; -.
DR EnsemblFungi; EGA59190; EGA59190; FOSTERSB_1043.
DR HOGENOM; CLU_141728_1_0_1; -.
DR GO; GO:0031083; C:BLOC-1 complex; IEA:InterPro.
DR InterPro; IPR034455; CNL1.
DR PANTHER; PTHR39145; PTHR39145; 1.
PE 3: Inferred from homology;
KW Coiled coil; Cytoplasm; Transport.
FT CHAIN 1..109
FT /note="Biogenesis of lysosome-related organelles complex 1
FT subunit CNL1"
FT /id="PRO_0000410651"
FT REGION 1..21
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 63..95
FT /evidence="ECO:0000255"
SQ SEQUENCE 109 AA; 12720 MW; 9A9402AA986EBACA CRC64;
MQDNSSHSRE SASAGDDPLG IDKLTVDYDY LLYKIRDYVQ SIQLDTTELC KKQNEVMVNG
IIENTIDKNI AKFKELLEKC DTLENHYEML NQLAIDNRYF QGKNRRGRK