ID   SYGB_SODGM              Reviewed;         689 AA.
AC   Q2NX38;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   07-FEB-2006, sequence version 1.
DT   03-AUG-2022, entry version 99.
DE   RecName: Full=Glycine--tRNA ligase beta subunit {ECO:0000255|HAMAP-Rule:MF_00255};
DE            EC=6.1.1.14 {ECO:0000255|HAMAP-Rule:MF_00255};
DE   AltName: Full=Glycyl-tRNA synthetase beta subunit {ECO:0000255|HAMAP-Rule:MF_00255};
DE            Short=GlyRS {ECO:0000255|HAMAP-Rule:MF_00255};
GN   Name=glyS {ECO:0000255|HAMAP-Rule:MF_00255}; OrderedLocusNames=SG0012;
OS   Sodalis glossinidius (strain morsitans).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Bruguierivoracaceae; Sodalis.
OX   NCBI_TaxID=343509;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=morsitans;
RX   PubMed=16365377; DOI=10.1101/gr.4106106;
RA   Toh H., Weiss B.L., Perkin S.A.H., Yamashita A., Oshima K., Hattori M.,
RA   Aksoy S.;
RT   "Massive genome erosion and functional adaptations provide insights into
RT   the symbiotic lifestyle of Sodalis glossinidius in the tsetse host.";
RL   Genome Res. 16:149-156(2006).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-
CC         tRNA(Gly); Xref=Rhea:RHEA:16013, Rhea:RHEA-COMP:9664, Rhea:RHEA-
CC         COMP:9683, ChEBI:CHEBI:30616, ChEBI:CHEBI:33019, ChEBI:CHEBI:57305,
CC         ChEBI:CHEBI:78442, ChEBI:CHEBI:78522, ChEBI:CHEBI:456215;
CC         EC=6.1.1.14; Evidence={ECO:0000255|HAMAP-Rule:MF_00255};
CC   -!- SUBUNIT: Tetramer of two alpha and two beta subunits.
CC       {ECO:0000255|HAMAP-Rule:MF_00255}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00255}.
CC   -!- SIMILARITY: Belongs to the class-II aminoacyl-tRNA synthetase family.
CC       {ECO:0000255|HAMAP-Rule:MF_00255}.
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DR   EMBL; AP008232; BAE73287.1; -; Genomic_DNA.
DR   RefSeq; WP_011409877.1; NZ_LN854557.1.
DR   AlphaFoldDB; Q2NX38; -.
DR   SMR; Q2NX38; -.
DR   STRING; 343509.SG0012; -.
DR   EnsemblBacteria; BAE73287; BAE73287; SG0012.
DR   KEGG; sgl:SG0012; -.
DR   eggNOG; COG0751; Bacteria.
DR   HOGENOM; CLU_007220_2_2_6; -.
DR   OMA; LPIPKRM; -.
DR   OrthoDB; 213210at2; -.
DR   BioCyc; SGLO343509:SGP1_RS00135-MON; -.
DR   Proteomes; UP000001932; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004814; F:arginine-tRNA ligase activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0004820; F:glycine-tRNA ligase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006420; P:arginyl-tRNA aminoacylation; IEA:InterPro.
DR   GO; GO:0006426; P:glycyl-tRNA aminoacylation; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00255; Gly_tRNA_synth_beta; 1.
DR   InterPro; IPR008909; DALR_anticod-bd.
DR   InterPro; IPR015944; Gly-tRNA-synth_bsu.
DR   InterPro; IPR006194; Gly-tRNA-synth_heterodimer.
DR   PANTHER; PTHR30075; PTHR30075; 1.
DR   Pfam; PF05746; DALR_1; 1.
DR   Pfam; PF02092; tRNA_synt_2f; 1.
DR   PRINTS; PR01045; TRNASYNTHGB.
DR   TIGRFAMs; TIGR00211; glyS; 1.
DR   PROSITE; PS50861; AA_TRNA_LIGASE_II_GLYAB; 1.
PE   3: Inferred from homology;
KW   Aminoacyl-tRNA synthetase; ATP-binding; Cytoplasm; Ligase;
KW   Nucleotide-binding; Protein biosynthesis.
FT   CHAIN           1..689
FT                   /note="Glycine--tRNA ligase beta subunit"
FT                   /id="PRO_1000006416"
SQ   SEQUENCE   689 AA;  76438 MW;  CF2800C4BACA0912 CRC64;
     MTQHTFLVEI GTEELPPKAL RALAEAFAIH ISGELDAANV RHGEVSWFAA PRRLAVKVAA
     LGGAQADSDV EKRGPAIAQV FDADGNPTKA AEGWARGCGI TVSQAERLAT DKGEWLVYRA
     RVKGQPVQEL LCAVVSRALG KLPIPKMMRW GDNETQFIRP VHTVTLLLDD GVIAGNVLGI
     DADRIVRGHR FMGEREISLE HADQYPQVLL DRGRVMADYL QRKETIRRDA EEAAKRLGGV
     ADLSESLLEE VTSLVEWPVV LTARFEEKFL AVPAEALVYT MKGDQKYFPV YDAAGNLLPH
     FIFVANIESK DPQQIIAGNE KVVRPRLADA EFFFNTDHKQ RLEDRLPRLD TVLFQKQLGT
     LRDKSDRIEA LSAWIAGRIG ADVPQAARAG LLSKCDLMTN MVFEFTDTQG VMGMHYARHD
     GEPEAVALAQ KEQYQPRFAG DALPTTLVSC AVAIADKMDT LAGIFGIGQH PKGDKDPFAL
     RRATLGVLRI IVEKQLPLDL QTLTEEAVRL YGEKLTNDAV VNDVIDFMLG RFRAWYQEQG
     HSVDTIQAVL ARRPTRPADF DARVRAVSYF RTLEEAASLA AANKRVSNIL AKSDDPVYKD
     LQASVLKDPS EITLATHLVV LREKLQPLFE AGRYQDALVE LAALREPVDA FFDSVMVMAD
     DPQVRINRLT LLAQLRKLFL QVADISLLQ