BL1S5_CAEEL
ID BL1S5_CAEEL Reviewed; 131 AA.
AC Q18446;
DT 28-NOV-2012, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2003, sequence version 2.
DT 03-AUG-2022, entry version 99.
DE RecName: Full=Biogenesis of lysosome-related organelles complex 1 subunit 5;
DE Short=BLOC-1 subunit 5;
DE AltName: Full=Protein Muted homolog;
GN Name=mutd-1; ORFNames=C34D4.13;
OS Caenorhabditis elegans.
OC Eukaryota; Metazoa; Ecdysozoa; Nematoda; Chromadorea; Rhabditida;
OC Rhabditina; Rhabditomorpha; Rhabditoidea; Rhabditidae; Peloderinae;
OC Caenorhabditis.
OX NCBI_TaxID=6239;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=Bristol N2;
RX PubMed=9851916; DOI=10.1126/science.282.5396.2012;
RG The C. elegans sequencing consortium;
RT "Genome sequence of the nematode C. elegans: a platform for investigating
RT biology.";
RL Science 282:2012-2018(1998).
CC -!- FUNCTION: Component of the biogenesis of lysosome-related organelles
CC complex-1 (BLOC-1) involved in gut granule biogenesis.
CC -!- SUBUNIT: Component of the biogenesis of lysosome-related organelles
CC complex-1 (BLOC-1) composed at least of blos-1, blos-2, blos-4, dsbn-1,
CC glo-2, mutd-1 and snpn-1.
CC -!- SIMILARITY: Belongs to the BLOC1S5 family. {ECO:0000305}.
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DR EMBL; FO080770; CCD66607.1; -; Genomic_DNA.
DR PIR; T29284; T29284.
DR RefSeq; NP_501119.2; NM_068718.2.
DR AlphaFoldDB; Q18446; -.
DR SMR; Q18446; -.
DR BioGRID; 48041; 1.
DR ComplexPortal; CPX-479; Bloc-1 complex.
DR STRING; 6239.C34D4.13; -.
DR EPD; Q18446; -.
DR PaxDb; Q18446; -.
DR PeptideAtlas; Q18446; -.
DR PRIDE; Q18446; -.
DR EnsemblMetazoa; C34D4.13.1; C34D4.13.1; WBGene00016404.
DR GeneID; 183210; -.
DR KEGG; cel:CELE_C34D4.13; -.
DR UCSC; C34D4.13; c. elegans.
DR CTD; 183210; -.
DR WormBase; C34D4.13; CE34735; WBGene00016404; mutd-1.
DR eggNOG; ENOG502SSKI; Eukaryota.
DR HOGENOM; CLU_1929446_0_0_1; -.
DR InParanoid; Q18446; -.
DR OMA; EPKYQKE; -.
DR OrthoDB; 1547233at2759; -.
DR PRO; PR:Q18446; -.
DR Proteomes; UP000001940; Chromosome IV.
DR Bgee; WBGene00016404; Expressed in embryo and 3 other tissues.
DR GO; GO:0031082; C:BLOC complex; IC:ComplexPortal.
DR GO; GO:0031083; C:BLOC-1 complex; TAS:UniProtKB.
DR GO; GO:0030133; C:transport vesicle; IEA:InterPro.
DR GO; GO:0016197; P:endosomal transport; IMP:UniProtKB.
DR GO; GO:1904757; P:positive regulation of gut granule assembly; IC:ComplexPortal.
DR InterPro; IPR017243; Bloc1s5.
DR Pfam; PF14942; Muted; 1.
PE 3: Inferred from homology;
KW Reference proteome.
FT CHAIN 1..131
FT /note="Biogenesis of lysosome-related organelles complex 1
FT subunit 5"
FT /id="PRO_0000420197"
SQ SEQUENCE 131 AA; 15467 MW; FD28B014262F33AE CRC64;
MATIPSVVRE ITLVGEQIFD HTQVVRAEID RFVERFERNE RHREFDGILR ASHALVESSE
TPVEGLFDMG KMEHMTQCVD DITKKLQTLV EPKYQKEHDV YLEKVKEDQK KYVDVCREQA
MNKMRSMTAH R