ID   BL1S5_DICDI             Reviewed;         158 AA.
AC   Q54TC6;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=Biogenesis of lysosome-related organelles complex 1 subunit 5;
DE            Short=BLOC-1 subunit 5;
DE   AltName: Full=Protein Muted homolog;
GN   Name=bloc1s5; Synonyms=muted; ORFNames=DDB_G0281859;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: Component of the BLOC-1 complex, a complex that is required
CC       for normal biogenesis of lysosome-related organelles (LRO). May play a
CC       role in intracellular vesicle trafficking (By similarity).
CC       {ECO:0000250}.
CC   -!- SUBUNIT: Component of the biogenesis of lysosome-related organelles
CC       complex 1 (BLOC-1). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the BLOC1S5 family. {ECO:0000305}.
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DR   EMBL; AAFI02000043; EAL66489.1; -; Genomic_DNA.
DR   RefSeq; XP_640463.1; XM_635371.1.
DR   AlphaFoldDB; Q54TC6; -.
DR   SMR; Q54TC6; -.
DR   STRING; 44689.DDB0204251; -.
DR   PaxDb; Q54TC6; -.
DR   EnsemblProtists; EAL66489; EAL66489; DDB_G0281859.
DR   GeneID; 8623276; -.
DR   KEGG; ddi:DDB_G0281859; -.
DR   dictyBase; DDB_G0281859; bloc1s5.
DR   eggNOG; ENOG502RHUK; Eukaryota.
DR   HOGENOM; CLU_1672525_0_0_1; -.
DR   InParanoid; Q54TC6; -.
DR   OMA; YQSHRDS; -.
DR   PRO; PR:Q54TC6; -.
DR   Proteomes; UP000002195; Chromosome 3.
DR   GO; GO:0031083; C:BLOC-1 complex; IBA:GO_Central.
DR   GO; GO:0030133; C:transport vesicle; IEA:InterPro.
DR   InterPro; IPR017243; Bloc1s5.
DR   PANTHER; PTHR31784; PTHR31784; 1.
DR   Pfam; PF14942; Muted; 1.
DR   PIRSF; PIRSF037610; BLOC-1_complex_muted_subunit; 1.
PE   2: Evidence at transcript level;
KW   Reference proteome.
FT   CHAIN           1..158
FT                   /note="Biogenesis of lysosome-related organelles complex 1
FT                   subunit 5"
FT                   /id="PRO_0000330838"
SQ   SEQUENCE   158 AA;  18729 MW;  934A5B74CD97060D CRC64;
     MNPKDKRVNF GSMEPLIRDI GTVYEFYFDQ NTFIESEIKT FLKEFETKRG DRDLYSLSQQ
     TINANNTIVN INRSIHQSSQ FLENINNNLN QINSKLSTQV ENESIHQEQR NNDRLNKFEL
     ELVEKKSIED SFNQRKSQIE NDFNEKASVL RDKYQIVL