ID   SYGB_SYNC1              Reviewed;         688 AA.
AC   Q3A8N5;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   22-NOV-2005, sequence version 1.
DT   25-MAY-2022, entry version 97.
DE   RecName: Full=Glycine--tRNA ligase beta subunit {ECO:0000255|HAMAP-Rule:MF_00255};
DE            EC=6.1.1.14 {ECO:0000255|HAMAP-Rule:MF_00255};
DE   AltName: Full=Glycyl-tRNA synthetase beta subunit {ECO:0000255|HAMAP-Rule:MF_00255};
DE            Short=GlyRS {ECO:0000255|HAMAP-Rule:MF_00255};
GN   Name=glyS {ECO:0000255|HAMAP-Rule:MF_00255}; OrderedLocusNames=Pcar_0599;
OS   Syntrophotalea carbinolica (strain DSM 2380 / NBRC 103641 / GraBd1)
OS   (Pelobacter carbinolicus).
OC   Bacteria; Proteobacteria; Deltaproteobacteria; Desulfuromonadales;
OC   Syntrophotaleaceae; Syntrophotalea.
OX   NCBI_TaxID=338963;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 2380 / NBRC 103641 / GraBd1;
RA   Copeland A., Lucas S., Lapidus A., Barry K., Detter J.C., Glavina T.,
RA   Hammon N., Israni S., Pitluck S., Chertkov O., Schmutz J., Larimer F.,
RA   Land M., Kyrpides N., Ivanova N., Richardson P.;
RT   "Complete sequence of Pelobacter carbinolicus DSM 2380.";
RL   Submitted (OCT-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-
CC         tRNA(Gly); Xref=Rhea:RHEA:16013, Rhea:RHEA-COMP:9664, Rhea:RHEA-
CC         COMP:9683, ChEBI:CHEBI:30616, ChEBI:CHEBI:33019, ChEBI:CHEBI:57305,
CC         ChEBI:CHEBI:78442, ChEBI:CHEBI:78522, ChEBI:CHEBI:456215;
CC         EC=6.1.1.14; Evidence={ECO:0000255|HAMAP-Rule:MF_00255};
CC   -!- SUBUNIT: Tetramer of two alpha and two beta subunits.
CC       {ECO:0000255|HAMAP-Rule:MF_00255}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00255}.
CC   -!- SIMILARITY: Belongs to the class-II aminoacyl-tRNA synthetase family.
CC       {ECO:0000255|HAMAP-Rule:MF_00255}.
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DR   EMBL; CP000142; ABA87858.1; -; Genomic_DNA.
DR   RefSeq; WP_011340299.1; NC_007498.2.
DR   AlphaFoldDB; Q3A8N5; -.
DR   SMR; Q3A8N5; -.
DR   STRING; 338963.Pcar_0599; -.
DR   EnsemblBacteria; ABA87858; ABA87858; Pcar_0599.
DR   KEGG; pca:Pcar_0599; -.
DR   eggNOG; COG0751; Bacteria.
DR   HOGENOM; CLU_007220_2_2_7; -.
DR   OMA; LPIPKRM; -.
DR   OrthoDB; 213210at2; -.
DR   Proteomes; UP000002534; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0004820; F:glycine-tRNA ligase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006426; P:glycyl-tRNA aminoacylation; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00255; Gly_tRNA_synth_beta; 1.
DR   InterPro; IPR015944; Gly-tRNA-synth_bsu.
DR   InterPro; IPR006194; Gly-tRNA-synth_heterodimer.
DR   PANTHER; PTHR30075; PTHR30075; 1.
DR   Pfam; PF02092; tRNA_synt_2f; 1.
DR   PRINTS; PR01045; TRNASYNTHGB.
DR   TIGRFAMs; TIGR00211; glyS; 1.
DR   PROSITE; PS50861; AA_TRNA_LIGASE_II_GLYAB; 1.
PE   3: Inferred from homology;
KW   Aminoacyl-tRNA synthetase; ATP-binding; Cytoplasm; Ligase;
KW   Nucleotide-binding; Protein biosynthesis; Reference proteome.
FT   CHAIN           1..688
FT                   /note="Glycine--tRNA ligase beta subunit"
FT                   /id="PRO_1000006382"
SQ   SEQUENCE   688 AA;  75602 MW;  4ED184E2B25A5304 CRC64;
     MSAELFLEIG TEEIPAGFLP TAMADLERLI RKELETGRIG FETVRTFATP RRLVLAVTGV
     ASGQARQEVT ASGPSVSVAF DADGNPTKAA LGFARSNGVE VSDLERRETD KGEYLFVSKV
     VEGRPTGELL PEMLPRIIAA IPFKKSMRWK DLDIRFARPM HWIVALFDGQ VVPFSYGNLT
     SGNLSYGHRF MAPDAFEVSS LEQYLVEAEK HFVIVDPVKR RQIISDQLAE VVGRCGGKLN
     PDDDLLDEVA FLVEYPAAVM GGFEDSYLQL PPELLITVMR EHQRYFTVVD DSGKLLPRFI
     TISNTRAEDL TVVQQGNERV LRARLSDAMF FWNEDRKVKL ESRLDALKNV VYQAKLGTSY
     EKVMRFKTLA VELAQQQVPE VVELTERAAS LAKCDLETGM VFEFTELQGV MGREYALLDG
     EDPRVARAIF EHYLPVQAGG ELPGDDVGAF VSIADKIDSI CGCFGVGLIP TGTADPFALR
     RSAIGILNII LDRGYRLSLP ALVERSLGLL ADKLTRPATE VAADVLEFLR LRFFNMLTAQ
     GLPNDVVDAV LSAAFEDPVD ALQRVKGLAS FREEGEFEAL AVTFKRVVNI VKGGVDTSVD
     SALFEADCEA GLFDALQNVT GRFEQFVAEG AYLDALRTVG GLRSPVDALF EGVMVMSPDE
     AVKTNRLALL TAVARLFQGI ADFSKIAA