ID   SYGB_THEYD              Reviewed;         679 AA.
AC   B5YJ12;
DT   24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT   25-NOV-2008, sequence version 1.
DT   25-MAY-2022, entry version 75.
DE   RecName: Full=Glycine--tRNA ligase beta subunit {ECO:0000255|HAMAP-Rule:MF_00255};
DE            EC=6.1.1.14 {ECO:0000255|HAMAP-Rule:MF_00255};
DE   AltName: Full=Glycyl-tRNA synthetase beta subunit {ECO:0000255|HAMAP-Rule:MF_00255};
DE            Short=GlyRS {ECO:0000255|HAMAP-Rule:MF_00255};
GN   Name=glyS {ECO:0000255|HAMAP-Rule:MF_00255}; OrderedLocusNames=THEYE_A2099;
OS   Thermodesulfovibrio yellowstonii (strain ATCC 51303 / DSM 11347 / YP87).
OC   Bacteria; Nitrospirae; Thermodesulfovibrionia; Thermodesulfovibrionales;
OC   Thermodesulfovibrionaceae; Thermodesulfovibrio.
OX   NCBI_TaxID=289376;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51303 / DSM 11347 / YP87;
RA   Dodson R.J., Durkin A.S., Wu M., Eisen J., Sutton G.;
RT   "The complete genome sequence of Thermodesulfovibrio yellowstonii strain
RT   ATCC 51303 / DSM 11347 / YP87.";
RL   Submitted (AUG-2008) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-
CC         tRNA(Gly); Xref=Rhea:RHEA:16013, Rhea:RHEA-COMP:9664, Rhea:RHEA-
CC         COMP:9683, ChEBI:CHEBI:30616, ChEBI:CHEBI:33019, ChEBI:CHEBI:57305,
CC         ChEBI:CHEBI:78442, ChEBI:CHEBI:78522, ChEBI:CHEBI:456215;
CC         EC=6.1.1.14; Evidence={ECO:0000255|HAMAP-Rule:MF_00255};
CC   -!- SUBUNIT: Tetramer of two alpha and two beta subunits.
CC       {ECO:0000255|HAMAP-Rule:MF_00255}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00255}.
CC   -!- SIMILARITY: Belongs to the class-II aminoacyl-tRNA synthetase family.
CC       {ECO:0000255|HAMAP-Rule:MF_00255}.
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DR   EMBL; CP001147; ACI20176.1; -; Genomic_DNA.
DR   RefSeq; WP_012544914.1; NC_011296.1.
DR   RefSeq; YP_002249886.1; NC_011296.1.
DR   AlphaFoldDB; B5YJ12; -.
DR   SMR; B5YJ12; -.
DR   STRING; 289376.THEYE_A2099; -.
DR   EnsemblBacteria; ACI20176; ACI20176; THEYE_A2099.
DR   KEGG; tye:THEYE_A2099; -.
DR   PATRIC; fig|289376.4.peg.2047; -.
DR   eggNOG; COG0751; Bacteria.
DR   HOGENOM; CLU_007220_2_2_0; -.
DR   InParanoid; B5YJ12; -.
DR   OMA; LPIPKRM; -.
DR   OrthoDB; 213210at2; -.
DR   Proteomes; UP000000718; Chromosome.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0004814; F:arginine-tRNA ligase activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0004820; F:glycine-tRNA ligase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006420; P:arginyl-tRNA aminoacylation; IEA:InterPro.
DR   GO; GO:0006426; P:glycyl-tRNA aminoacylation; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00255; Gly_tRNA_synth_beta; 1.
DR   InterPro; IPR008909; DALR_anticod-bd.
DR   InterPro; IPR015944; Gly-tRNA-synth_bsu.
DR   InterPro; IPR006194; Gly-tRNA-synth_heterodimer.
DR   InterPro; IPR009080; tRNAsynth_Ia_anticodon-bd.
DR   PANTHER; PTHR30075; PTHR30075; 1.
DR   Pfam; PF05746; DALR_1; 1.
DR   Pfam; PF02092; tRNA_synt_2f; 1.
DR   PRINTS; PR01045; TRNASYNTHGB.
DR   SMART; SM00836; DALR_1; 1.
DR   SUPFAM; SSF47323; SSF47323; 1.
DR   TIGRFAMs; TIGR00211; glyS; 1.
DR   PROSITE; PS50861; AA_TRNA_LIGASE_II_GLYAB; 1.
PE   3: Inferred from homology;
KW   Aminoacyl-tRNA synthetase; ATP-binding; Cytoplasm; Ligase;
KW   Nucleotide-binding; Protein biosynthesis; Reference proteome.
FT   CHAIN           1..679
FT                   /note="Glycine--tRNA ligase beta subunit"
FT                   /id="PRO_1000101366"
SQ   SEQUENCE   679 AA;  78736 MW;  BC7BB017C43AFE0D CRC64;
     MGKILFEIGA EEIPARFIPL AISQIEENFK KITSEYRIEL ESIKVYATPR RLTLLAELSS
     EQASEEKLVW GPPVHVAFDE KGLPKESAYA FAKAQGIEVD QLQIKPKGKG NYVCAVLSKK
     GKKTEEVLPE ILRNLFYSLN FPKMMRWGEG TLRFIRPVRW FLALYDDRFI SFEIEGIKTE
     NKTQGHRFLS ENPLNIDRVD NYEFILEKAF VIVDPEKRKK IILTQAEELA KKVNGKILWN
     NELIEEVTYL VEFPNSVLCS FSMQYLKLPE ELLITVMKDH QRYFAIIDNE GKLKNYFVVV
     SNTKAENEEN IKKGAERVIK ARFEDARFYY EEDLKKGLVN LLEATKGIIY HKKLGSLYDK
     SLRIIRIAER LSDRLIPEKT ELVKIAANYC KADLASGVVG EFPELQGIMG GYYAKNAGMP
     EEVFLAIREH YLPKGFTDEI PSNDIGCIIS LADKLDHIAT FFYLGEIPSG TEDPFGLRRA
     ANGIISILLK KKYSLSLLET VSMIQEFVDE KLKEQISIFI VQRFESYLES TGYDVNLIKT
     ISDFILIRPV YEIKKRLEAV SLFRSKEDFE EFFLAVKRVS NIIKNYEKFE LNPELFSSEE
     EKKLFNEIEK YKENLYEYLN SQQFFEALNY LHKLTPTINN FFDNVLVMDK DEKIKRNRLA
     LLQHLSELLK SVADISRLY