ID   SYGB_VESOH              Reviewed;         677 AA.
AC   A5CW91;
DT   24-MAR-2009, integrated into UniProtKB/Swiss-Prot.
DT   12-JUN-2007, sequence version 1.
DT   03-AUG-2022, entry version 77.
DE   RecName: Full=Glycine--tRNA ligase beta subunit {ECO:0000255|HAMAP-Rule:MF_00255};
DE            EC=6.1.1.14 {ECO:0000255|HAMAP-Rule:MF_00255};
DE   AltName: Full=Glycyl-tRNA synthetase beta subunit {ECO:0000255|HAMAP-Rule:MF_00255};
DE            Short=GlyRS {ECO:0000255|HAMAP-Rule:MF_00255};
GN   Name=glyS {ECO:0000255|HAMAP-Rule:MF_00255}; OrderedLocusNames=COSY_0669;
OS   Vesicomyosocius okutanii subsp. Calyptogena okutanii (strain HA).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; sulfur-oxidizing symbionts;
OC   Candidatus Vesicomyosocius.
OX   NCBI_TaxID=412965;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=HA;
RX   PubMed=17493812; DOI=10.1016/j.cub.2007.04.039;
RA   Kuwahara H., Yoshida T., Takaki Y., Shimamura S., Nishi S., Harada M.,
RA   Matsuyama K., Takishita K., Kawato M., Uematsu K., Fujiwara Y., Sato T.,
RA   Kato C., Kitagawa M., Kato I., Maruyama T.;
RT   "Reduced genome of the thioautotrophic intracellular symbiont in a deep-sea
RT   clam, Calyptogena okutanii.";
RL   Curr. Biol. 17:881-886(2007).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-
CC         tRNA(Gly); Xref=Rhea:RHEA:16013, Rhea:RHEA-COMP:9664, Rhea:RHEA-
CC         COMP:9683, ChEBI:CHEBI:30616, ChEBI:CHEBI:33019, ChEBI:CHEBI:57305,
CC         ChEBI:CHEBI:78442, ChEBI:CHEBI:78522, ChEBI:CHEBI:456215;
CC         EC=6.1.1.14; Evidence={ECO:0000255|HAMAP-Rule:MF_00255};
CC   -!- SUBUNIT: Tetramer of two alpha and two beta subunits.
CC       {ECO:0000255|HAMAP-Rule:MF_00255}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_00255}.
CC   -!- SIMILARITY: Belongs to the class-II aminoacyl-tRNA synthetase family.
CC       {ECO:0000255|HAMAP-Rule:MF_00255}.
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DR   EMBL; AP009247; BAF61781.1; -; Genomic_DNA.
DR   RefSeq; WP_011930051.1; NC_009465.1.
DR   AlphaFoldDB; A5CW91; -.
DR   SMR; A5CW91; -.
DR   STRING; 412965.COSY_0669; -.
DR   PRIDE; A5CW91; -.
DR   EnsemblBacteria; BAF61781; BAF61781; COSY_0669.
DR   KEGG; vok:COSY_0669; -.
DR   eggNOG; COG0751; Bacteria.
DR   HOGENOM; CLU_007220_2_2_6; -.
DR   OMA; LPIPKRM; -.
DR   OrthoDB; 213210at2; -.
DR   Proteomes; UP000000247; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0004814; F:arginine-tRNA ligase activity; IEA:InterPro.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0004820; F:glycine-tRNA ligase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0006420; P:arginyl-tRNA aminoacylation; IEA:InterPro.
DR   GO; GO:0006426; P:glycyl-tRNA aminoacylation; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_00255; Gly_tRNA_synth_beta; 1.
DR   InterPro; IPR008909; DALR_anticod-bd.
DR   InterPro; IPR015944; Gly-tRNA-synth_bsu.
DR   InterPro; IPR006194; Gly-tRNA-synth_heterodimer.
DR   PANTHER; PTHR30075; PTHR30075; 1.
DR   Pfam; PF05746; DALR_1; 1.
DR   Pfam; PF02092; tRNA_synt_2f; 1.
DR   PRINTS; PR01045; TRNASYNTHGB.
DR   TIGRFAMs; TIGR00211; glyS; 1.
DR   PROSITE; PS50861; AA_TRNA_LIGASE_II_GLYAB; 1.
PE   3: Inferred from homology;
KW   Aminoacyl-tRNA synthetase; ATP-binding; Cytoplasm; Ligase;
KW   Nucleotide-binding; Protein biosynthesis.
FT   CHAIN           1..677
FT                   /note="Glycine--tRNA ligase beta subunit"
FT                   /id="PRO_1000101369"
SQ   SEQUENCE   677 AA;  76481 MW;  D2BD730FF00AF172 CRC64;
     MNTQDFLLEL GCEELPPKNL QHLSNALTYN LTTEFDKLKL SYSSVESFAT PRRLAVLVNG
     LQLQQNNQTI ERKGPLISEL DKAIEGFAKS CGVARNMLTQ KAFGKIQYYF FTKQQIGLKT
     IDLLESVVNT AIQNIPIAKP MRWSNLDTYF VRPVHWLIMM LGSDVVPASI MGLISSNITR
     GLRFTDECIF DIICAKDYQK TLLEKAQIEV DFDMRKAIIR KQIIHVAQNN NATAVIDESL
     LDEVCALVEY PCVFSGNFSS KFLDIPEEVL ISVMKSYQKY FHMLDMNGNL MSSFISVANI
     ESSDLSVIID GNERVIRSRL SDSEFFWIQD KAYTLEFRLD RLNQVLFMKS LGSMGDKAKR
     IEILSGYIAG VIGANVKDSS RAGLLCKSDL VTDMVGEFAD LQGVMGGYYA FNDGENKAVS
     VAISEHYQPR FSGDSLPNTI EGLVVSIADK LDTITGIFGI GQGPTGSKDP YALRRMALGL
     LRIILESKFH INLKELISES LNAHLSVVNT NKANDIYQFM MERLRSYYKK HEVSMQVFDA
     VLAVCPESPY DFHLRIRALN TFTNNQELEN LIEINKRISN ILKNCSDLSI KVDDSVLIET
     AEKTLFKATK ILAKRISNSI NYTKNMKELI ALKDMIDEFF DKVMVNTDDV ELRQARLNLI
     NWVRSLFLSV ADISYLV