BL1S5_NEMVE
ID BL1S5_NEMVE Reviewed; 164 AA.
AC A7SPE8;
DT 29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT 02-OCT-2007, sequence version 1.
DT 25-MAY-2022, entry version 51.
DE RecName: Full=Biogenesis of lysosome-related organelles complex 1 subunit 5;
DE Short=BLOC-1 subunit 5;
DE AltName: Full=Protein Muted homolog;
GN Name=bloc1s5; Synonyms=muted; ORFNames=v1g246561;
OS Nematostella vectensis (Starlet sea anemone).
OC Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC Edwardsiidae; Nematostella.
OX NCBI_TaxID=45351;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=CH2 X CH6;
RX PubMed=17615350; DOI=10.1126/science.1139158;
RA Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA Technau U., Martindale M.Q., Rokhsar D.S.;
RT "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT genomic organization.";
RL Science 317:86-94(2007).
CC -!- FUNCTION: Component of the BLOC-1 complex, a complex that is required
CC for normal biogenesis of lysosome-related organelles (LRO). May play a
CC role in intracellular vesicle trafficking (By similarity).
CC {ECO:0000250}.
CC -!- SUBUNIT: Component of the biogenesis of lysosome-related organelles
CC complex 1 (BLOC-1). {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the BLOC1S5 family. {ECO:0000305}.
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DR EMBL; DS469732; EDO34439.1; -; Genomic_DNA.
DR RefSeq; XP_001626539.1; XM_001626489.1.
DR AlphaFoldDB; A7SPE8; -.
DR SMR; A7SPE8; -.
DR STRING; 45351.EDO34439; -.
DR EnsemblMetazoa; EDO34439; EDO34439; NEMVEDRAFT_v1g246561.
DR GeneID; 5505759; -.
DR KEGG; nve:5505759; -.
DR eggNOG; ENOG502SGGQ; Eukaryota.
DR HOGENOM; CLU_110751_1_0_1; -.
DR InParanoid; A7SPE8; -.
DR OMA; QGEICYF; -.
DR OrthoDB; 1593497at2759; -.
DR PhylomeDB; A7SPE8; -.
DR Proteomes; UP000001593; Unassembled WGS sequence.
DR GO; GO:0031083; C:BLOC-1 complex; IBA:GO_Central.
DR GO; GO:0030133; C:transport vesicle; IEA:InterPro.
DR InterPro; IPR017243; Bloc1s5.
DR PANTHER; PTHR31784; PTHR31784; 1.
DR Pfam; PF14942; Muted; 1.
PE 3: Inferred from homology;
KW Coiled coil; Reference proteome.
FT CHAIN 1..164
FT /note="Biogenesis of lysosome-related organelles complex 1
FT subunit 5"
FT /id="PRO_0000330839"
FT COILED 36..91
FT /evidence="ECO:0000255"
SQ SEQUENCE 164 AA; 19652 MW; F633BB8DD29584FD CRC64;
MAGEKMVRDI SGVYARLFDH RAVLQAECKY MLREFEGKRN DRELERLRES EQKIRQVQEE
IPKCITESVK LKDLLEELKV AREKCHEILV KEEQDLFKER REEIFIESKK NWETFIGEIA
EEEKRIEEEF EQSAEKLRAR YGVQLVRNPK EPDDKGELQP QEIA