ID   BL1S5_XENTR             Reviewed;         185 AA.
AC   A9ULR1;
DT   29-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   05-FEB-2008, sequence version 1.
DT   03-AUG-2022, entry version 41.
DE   RecName: Full=Biogenesis of lysosome-related organelles complex 1 subunit 5;
DE            Short=BLOC-1 subunit 5;
DE   AltName: Full=Protein Muted homolog;
GN   Name=bloc1s5; Synonyms=muted;
OS   Xenopus tropicalis (Western clawed frog) (Silurana tropicalis).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia;
OC   Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Silurana.
OX   NCBI_TaxID=8364;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   TISSUE=Embryo;
RG   NIH - Xenopus Gene Collection (XGC) project;
RL   Submitted (DEC-2007) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Component of the BLOC-1 complex, a complex that is required
CC       for normal biogenesis of lysosome-related organelles (LRO), such as
CC       platelet dense granules and melanosomes. Plays a role in intracellular
CC       vesicle trafficking (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Component of the biogenesis of lysosome-related organelles
CC       complex 1 (BLOC-1). {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the BLOC1S5 family. {ECO:0000305}.
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DR   EMBL; BC157360; AAI57361.1; -; mRNA.
DR   RefSeq; NP_001107140.1; NM_001113668.1.
DR   AlphaFoldDB; A9ULR1; -.
DR   SMR; A9ULR1; -.
DR   PRIDE; A9ULR1; -.
DR   GeneID; 100101667; -.
DR   KEGG; xtr:100101667; -.
DR   CTD; 63915; -.
DR   Xenbase; XB-GENE-919985; bloc1s5.
DR   InParanoid; A9ULR1; -.
DR   OrthoDB; 1593497at2759; -.
DR   Proteomes; UP000008143; Chromosome 6.
DR   Proteomes; UP000790000; Unplaced.
DR   GO; GO:0031083; C:BLOC-1 complex; IBA:GO_Central.
DR   GO; GO:0030133; C:transport vesicle; IEA:InterPro.
DR   InterPro; IPR017243; Bloc1s5.
DR   PANTHER; PTHR31784; PTHR31784; 1.
DR   Pfam; PF14942; Muted; 1.
DR   PIRSF; PIRSF037610; BLOC-1_complex_muted_subunit; 1.
PE   2: Evidence at transcript level;
KW   Coiled coil; Reference proteome.
FT   CHAIN           1..185
FT                   /note="Biogenesis of lysosome-related organelles complex 1
FT                   subunit 5"
FT                   /id="PRO_0000330837"
FT   REGION          1..24
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COILED          98..182
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   185 AA;  21634 MW;  C8E056A968E80AAB CRC64;
     MSSSNSPVKS TGSPFIQSLK PRDNLASMGS STQLIIKDIG EIHSRLLDHR PVIQGETRYF
     IKEFEEKRGL REMRVLENLR NSISETNEHD LPKCTDVMQD QLASVLKKLE TANHTIHRLQ
     QRELETAKEI ASRAGDQMMR AHWEPFMKEQ EQRRRTVDEE HRKAVMRLKD QYVTMEKELS
     KQISF