SYHC_ORYSJ
ID SYHC_ORYSJ Reviewed; 788 AA.
AC P93422; A0A0P0WI08; Q0DKP0; Q5WN00;
DT 15-DEC-1998, integrated into UniProtKB/Swiss-Prot.
DT 27-JUN-2006, sequence version 2.
DT 25-MAY-2022, entry version 124.
DE RecName: Full=Histidine--tRNA ligase, cytoplasmic {ECO:0000305};
DE EC=6.1.1.21 {ECO:0000305};
DE AltName: Full=Histidyl-tRNA synthetase {ECO:0000305};
DE Short=HisRS {ECO:0000305};
GN OrderedLocusNames=Os05g0150900, LOC_Os05g05840; ORFNames=P0001A07.8;
OS Oryza sativa subsp. japonica (Rice).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; Liliopsida; Poales; Poaceae; BOP clade;
OC Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa.
OX NCBI_TaxID=39947;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16261349; DOI=10.1007/s00438-005-0039-y;
RA Cheng C.-H., Chung M.C., Liu S.-M., Chen S.-K., Kao F.Y., Lin S.-J.,
RA Hsiao S.-H., Tseng I.C., Hsing Y.-I.C., Wu H.-P., Chen C.-S., Shaw J.-F.,
RA Wu J., Matsumoto T., Sasaki T., Chen H.-C., Chow T.-Y.;
RT "A fine physical map of the rice chromosome 5.";
RL Mol. Genet. Genomics 274:337-345(2005).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=16100779; DOI=10.1038/nature03895;
RG International rice genome sequencing project (IRGSP);
RT "The map-based sequence of the rice genome.";
RL Nature 436:793-800(2005).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=18089549; DOI=10.1093/nar/gkm978;
RG The rice annotation project (RAP);
RT "The rice annotation project database (RAP-DB): 2008 update.";
RL Nucleic Acids Res. 36:D1028-D1033(2008).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Nipponbare;
RX PubMed=24280374; DOI=10.1186/1939-8433-6-4;
RA Kawahara Y., de la Bastide M., Hamilton J.P., Kanamori H., McCombie W.R.,
RA Ouyang S., Schwartz D.C., Tanaka T., Wu J., Zhou S., Childs K.L.,
RA Davidson R.M., Lin H., Quesada-Ocampo L., Vaillancourt B., Sakai H.,
RA Lee S.S., Kim J., Numa H., Itoh T., Buell C.R., Matsumoto T.;
RT "Improvement of the Oryza sativa Nipponbare reference genome using next
RT generation sequence and optical map data.";
RL Rice 6:4-4(2013).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Nipponbare;
RX PubMed=12869764; DOI=10.1126/science.1081288;
RG The rice full-length cDNA consortium;
RT "Collection, mapping, and annotation of over 28,000 cDNA clones from
RT japonica rice.";
RL Science 301:376-379(2003).
RN [6]
RP NUCLEOTIDE SEQUENCE [MRNA] OF 272-788.
RC STRAIN=cv. Nipponbare;
RA Akashi K., Small I.D.;
RT "A cDNA clone encoding rice histidyl-tRNA synthetase.";
RL (er) Plant Gene Register PGR97-062(1997).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=ATP + L-histidine + tRNA(His) = AMP + diphosphate + H(+) + L-
CC histidyl-tRNA(His); Xref=Rhea:RHEA:17313, Rhea:RHEA-COMP:9665,
CC Rhea:RHEA-COMP:9689, ChEBI:CHEBI:15378, ChEBI:CHEBI:30616,
CC ChEBI:CHEBI:33019, ChEBI:CHEBI:57595, ChEBI:CHEBI:78442,
CC ChEBI:CHEBI:78527, ChEBI:CHEBI:456215; EC=6.1.1.21;
CC -!- SUBUNIT: Homodimer. {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the class-II aminoacyl-tRNA synthetase family.
CC {ECO:0000305}.
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DR EMBL; AC084218; AAV32201.1; -; Genomic_DNA.
DR EMBL; AP008211; BAF16583.1; -; Genomic_DNA.
DR EMBL; AP014961; BAS92308.1; -; Genomic_DNA.
DR EMBL; AK099789; -; NOT_ANNOTATED_CDS; mRNA.
DR EMBL; Z85984; CAB06653.1; -; mRNA.
DR PIR; T03774; T03774.
DR AlphaFoldDB; P93422; -.
DR SMR; P93422; -.
DR STRING; 4530.OS05T0150900-02; -.
DR PaxDb; P93422; -.
DR EnsemblPlants; Os05t0150900-01; Os05t0150900-01; Os05g0150900.
DR Gramene; Os05t0150900-01; Os05t0150900-01; Os05g0150900.
DR eggNOG; KOG1936; Eukaryota.
DR InParanoid; P93422; -.
DR BRENDA; 6.1.1.21; 4460.
DR Proteomes; UP000000763; Chromosome 5.
DR Proteomes; UP000059680; Chromosome 5.
DR ExpressionAtlas; P93422; baseline and differential.
DR Genevisible; P93422; OS.
DR GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR GO; GO:0004821; F:histidine-tRNA ligase activity; IBA:GO_Central.
DR GO; GO:0006427; P:histidyl-tRNA aminoacylation; IBA:GO_Central.
DR GO; GO:0032543; P:mitochondrial translation; IBA:GO_Central.
DR CDD; cd00773; HisRS-like_core; 1.
DR CDD; cd00859; HisRS_anticodon; 1.
DR Gene3D; 3.30.930.10; -; 1.
DR Gene3D; 3.40.50.800; -; 1.
DR HAMAP; MF_00127; His_tRNA_synth; 1.
DR InterPro; IPR006195; aa-tRNA-synth_II.
DR InterPro; IPR045864; aa-tRNA-synth_II/BPL/LPL.
DR InterPro; IPR004154; Anticodon-bd.
DR InterPro; IPR036621; Anticodon-bd_dom_sf.
DR InterPro; IPR001106; Aromatic_Lyase.
DR InterPro; IPR015807; His-tRNA-ligase.
DR InterPro; IPR041715; HisRS-like_core.
DR InterPro; IPR033656; HisRS_anticodon.
DR InterPro; IPR008948; L-Aspartase-like.
DR Pfam; PF03129; HGTP_anticodon; 1.
DR Pfam; PF00221; Lyase_aromatic; 1.
DR Pfam; PF13393; tRNA-synt_His; 1.
DR SUPFAM; SSF48557; SSF48557; 1.
DR SUPFAM; SSF55681; SSF55681; 1.
DR TIGRFAMs; TIGR00442; hisS; 1.
DR PROSITE; PS50862; AA_TRNA_LIGASE_II; 1.
PE 2: Evidence at transcript level;
KW Aminoacyl-tRNA synthetase; ATP-binding; Ligase; Nucleotide-binding;
KW Protein biosynthesis; Reference proteome.
FT CHAIN 1..788
FT /note="Histidine--tRNA ligase, cytoplasmic"
FT /id="PRO_0000136339"
FT REGION 252..286
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 788 AA; 85548 MW; 41E135A5EA989123 CRC64;
MAPPAAAAAV TLGGKGAALT PAAVYALSHG LADPAIDCCA SPLVRVADAV AALSCEAARG
DVAAFDVPTS GDGLSAKDEA DVAADVKMLL FGSKLVGAAG GADAASFTKV PTVNGIFREA
VRALHARVRI ELNAPVKLGK RDAVQTGEGK EEALVALATQ LARPVQAMLK LSVARARLCV
ARIDDAELRK KLTDGVEIDD LKGMLGKVTI DSDAVSVLRG VYNSLLKFRD ILAWEAAVAM
AVIEMDSSIE KPQACEENEA GSSTENPHAS GEKPKGDKKS KKKKTLGKGT SAVLMLLRDL
VTNGKEVLSV NSALLAEWGT ELSLLFDPKC PRLVSLVDKV KEIVETNEVR RLPKIPKGTR
DFGKEQMAIR EHAFSIITGV FKMHGAVSLD TPVFELRETL MGKYGEDSKL IYDLADQGGE
LCSLRYDLTV PFARYVAMNN ISSLKRYQIA KVYRRDNPSK GRYREFYQCD FDIAGVYETM
EPDFEVIKVL TELLDQLDIG TYEIKLNHRK LLDGMLEICG VPPEKFRTVC SSIDKLDKQT
FEQVKKELVD EKGISNETAD KIGDLVKTRG PPLEVLLELR KEGSKFMGNA GSVTALNELE
ILFKALDKAN AIGKIVFDLS LARGLDYYTG VIYEAVFKGT TQVGSIAAGG RYDNLVGMFS
GKQVPAVGVS LGIERVFAIM EQQEMEKNQI RATETEVLVS IIGKDLILAA ELVSELWNAG
IKAEFKLTTR IQNHLKYATQ SGIPWMVLVG ESEISSGKVK LKNLAASQEE EVDRTEFAQV
LKQKLRNP
