BLACE_HUMAN
ID BLACE_HUMAN Reviewed; 179 AA.
AC A4D250;
DT 27-JUL-2011, integrated into UniProtKB/Swiss-Prot.
DT 05-SEP-2012, sequence version 2.
DT 03-AUG-2022, entry version 62.
DE RecName: Full=B-cell acute lymphoblastic leukemia-expressed protein;
GN Name=BLACE;
OS Homo sapiens (Human).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae;
OC Homo.
OX NCBI_TaxID=9606;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=14667812; DOI=10.1016/s0888-7543(03)00209-x;
RA Vialle-Castellano A., Laduron S., De Plaen E., Jost E., Dupont S.,
RA Ameye G., Michaux L., Coulie P., Olive D., Boon T., van Baren N.;
RT "A gene expressed exclusively in acute B lymphoblastic leukemias.";
RL Genomics 83:85-94(2004).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=12853948; DOI=10.1038/nature01782;
RA Hillier L.W., Fulton R.S., Fulton L.A., Graves T.A., Pepin K.H.,
RA Wagner-McPherson C., Layman D., Maas J., Jaeger S., Walker R., Wylie K.,
RA Sekhon M., Becker M.C., O'Laughlin M.D., Schaller M.E., Fewell G.A.,
RA Delehaunty K.D., Miner T.L., Nash W.E., Cordes M., Du H., Sun H.,
RA Edwards J., Bradshaw-Cordum H., Ali J., Andrews S., Isak A., Vanbrunt A.,
RA Nguyen C., Du F., Lamar B., Courtney L., Kalicki J., Ozersky P.,
RA Bielicki L., Scott K., Holmes A., Harkins R., Harris A., Strong C.M.,
RA Hou S., Tomlinson C., Dauphin-Kohlberg S., Kozlowicz-Reilly A., Leonard S.,
RA Rohlfing T., Rock S.M., Tin-Wollam A.-M., Abbott A., Minx P., Maupin R.,
RA Strowmatt C., Latreille P., Miller N., Johnson D., Murray J.,
RA Woessner J.P., Wendl M.C., Yang S.-P., Schultz B.R., Wallis J.W.,
RA Spieth J., Bieri T.A., Nelson J.O., Berkowicz N., Wohldmann P.E.,
RA Cook L.L., Hickenbotham M.T., Eldred J., Williams D., Bedell J.A.,
RA Mardis E.R., Clifton S.W., Chissoe S.L., Marra M.A., Raymond C., Haugen E.,
RA Gillett W., Zhou Y., James R., Phelps K., Iadanoto S., Bubb K., Simms E.,
RA Levy R., Clendenning J., Kaul R., Kent W.J., Furey T.S., Baertsch R.A.,
RA Brent M.R., Keibler E., Flicek P., Bork P., Suyama M., Bailey J.A.,
RA Portnoy M.E., Torrents D., Chinwalla A.T., Gish W.R., Eddy S.R.,
RA McPherson J.D., Olson M.V., Eichler E.E., Green E.D., Waterston R.H.,
RA Wilson R.K.;
RT "The DNA sequence of human chromosome 7.";
RL Nature 424:157-164(2003).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX PubMed=12690205; DOI=10.1126/science.1083423;
RA Scherer S.W., Cheung J., MacDonald J.R., Osborne L.R., Nakabayashi K.,
RA Herbrick J.-A., Carson A.R., Parker-Katiraee L., Skaug J., Khaja R.,
RA Zhang J., Hudek A.K., Li M., Haddad M., Duggan G.E., Fernandez B.A.,
RA Kanematsu E., Gentles S., Christopoulos C.C., Choufani S., Kwasnicka D.,
RA Zheng X.H., Lai Z., Nusskern D.R., Zhang Q., Gu Z., Lu F., Zeesman S.,
RA Nowaczyk M.J., Teshima I., Chitayat D., Shuman C., Weksberg R.,
RA Zackai E.H., Grebe T.A., Cox S.R., Kirkpatrick S.J., Rahman N.,
RA Friedman J.M., Heng H.H.Q., Pelicci P.G., Lo-Coco F., Belloni E.,
RA Shaffer L.G., Pober B., Morton C.C., Gusella J.F., Bruns G.A.P., Korf B.R.,
RA Quade B.J., Ligon A.H., Ferguson H., Higgins A.W., Leach N.T.,
RA Herrick S.R., Lemyre E., Farra C.G., Kim H.-G., Summers A.M., Gripp K.W.,
RA Roberts W., Szatmari P., Winsor E.J.T., Grzeschik K.-H., Teebi A.,
RA Minassian B.A., Kere J., Armengol L., Pujana M.A., Estivill X.,
RA Wilson M.D., Koop B.F., Tosi S., Moore G.E., Boright A.P., Zlotorynski E.,
RA Kerem B., Kroisel P.M., Petek E., Oscier D.G., Mould S.J., Doehner H.,
RA Doehner K., Rommens J.M., Vincent J.B., Venter J.C., Li P.W., Mural R.J.,
RA Adams M.D., Tsui L.-C.;
RT "Human chromosome 7: DNA sequence and biology.";
RL Science 300:767-772(2003).
CC -!- SEQUENCE CAUTION:
CC Sequence=AY166699; Type=Frameshift; Evidence={ECO:0000305};
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DR EMBL; AY166699; -; NOT_ANNOTATED_CDS; mRNA.
DR EMBL; AC142169; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CH236954; EAL23907.1; -; Genomic_DNA.
DR AlphaFoldDB; A4D250; -.
DR BioMuta; BLACE; -.
DR MassIVE; A4D250; -.
DR PaxDb; A4D250; -.
DR PRIDE; A4D250; -.
DR UCSC; uc033aqq.2; human.
DR GeneCards; BLACE; -.
DR HGNC; HGNC:20484; BLACE.
DR neXtProt; NX_A4D250; -.
DR eggNOG; ENOG502TDKH; Eukaryota.
DR HOGENOM; CLU_1502992_0_0_1; -.
DR InParanoid; A4D250; -.
DR PhylomeDB; A4D250; -.
DR SignaLink; A4D250; -.
DR Pharos; A4D250; Tdark.
DR PRO; PR:A4D250; -.
DR Proteomes; UP000005640; Unplaced.
DR RNAct; A4D250; protein.
PE 2: Evidence at transcript level;
KW Reference proteome.
FT CHAIN 1..179
FT /note="B-cell acute lymphoblastic leukemia-expressed
FT protein"
FT /id="PRO_0000411092"
FT REGION 1..20
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT REGION 65..86
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 179 AA; 19503 MW; BD23BA9A1A2251AF CRC64;
MMKDIIPASS WASEESTDLQ NGSFPLSVAP RSEFPRRRAL EDWLLSVFLA DQAESEGQLV
LERVRDTPPP VTSPRGDGIC VSRGKAPSSP GGSTHAWLYL TRHFPWSPFP HGGWTDTSEP
CVLETLGGSS LAALRGNSLW VQSSGACAFC VYESLIEQSL PNERFEELLL GPSPGEVMK