BLCAP_BOVIN
ID BLCAP_BOVIN Reviewed; 87 AA.
AC P62954; A5D976; O60629; Q17QQ8; Q9D3B5;
DT 31-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT 31-AUG-2004, sequence version 1.
DT 03-AUG-2022, entry version 83.
DE RecName: Full=Bladder cancer-associated protein;
GN Name=BLCAP;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Hahn Y.;
RT "Bovine mRNA for Blcap.";
RL Submitted (SEP-2001) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RX PubMed=16305752; DOI=10.1186/1471-2164-6-166;
RA Harhay G.P., Sonstegard T.S., Keele J.W., Heaton M.P., Clawson M.L.,
RA Snelling W.M., Wiedmann R.T., Van Tassell C.P., Smith T.P.L.;
RT "Characterization of 954 bovine full-CDS cDNA sequences.";
RL BMC Genomics 6:166-166(2005).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Hereford; TISSUE=Hippocampus;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (JUN-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May regulate cell proliferation and coordinate apoptosis and
CC cell cycle progression via a novel mechanism independent of both
CC p53/TP53 and nuclear factor kappa B (NF-kappaB). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the BLCAP family. {ECO:0000305}.
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DR EMBL; AB071597; BAB68125.1; -; mRNA.
DR EMBL; BT030495; ABQ12935.1; -; mRNA.
DR EMBL; BC118229; AAI18230.1; -; mRNA.
DR RefSeq; NP_776675.1; NM_174250.3.
DR RefSeq; XP_005214547.1; XM_005214490.3.
DR AlphaFoldDB; P62954; -.
DR STRING; 9913.ENSBTAP00000004167; -.
DR PaxDb; P62954; -.
DR PRIDE; P62954; -.
DR Ensembl; ENSBTAT00000004167; ENSBTAP00000004167; ENSBTAG00000003209.
DR GeneID; 281649; -.
DR KEGG; bta:281649; -.
DR CTD; 10904; -.
DR VEuPathDB; HostDB:ENSBTAG00000003209; -.
DR VGNC; VGNC:54701; BLCAP.
DR eggNOG; KOG4489; Eukaryota.
DR GeneTree; ENSGT00390000014105; -.
DR HOGENOM; CLU_181908_0_0_1; -.
DR InParanoid; P62954; -.
DR OMA; MERRPCY; -.
DR OrthoDB; 1521316at2759; -.
DR TreeFam; TF313306; -.
DR Proteomes; UP000009136; Chromosome 13.
DR Bgee; ENSBTAG00000003209; Expressed in adenohypophysis and 106 other tissues.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0030262; P:apoptotic nuclear changes; IEA:Ensembl.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR InterPro; IPR009598; BC10.
DR PANTHER; PTHR13259; PTHR13259; 1.
DR SMART; SM01396; BC10; 1.
PE 3: Inferred from homology;
KW Apoptosis; Cell cycle; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..87
FT /note="Bladder cancer-associated protein"
FT /id="PRO_0000064848"
FT TRANSMEM 19..39
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 43..63
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 87 AA; 9876 MW; 06A45C03E27D3E87 CRC64;
MYCLQWLLPV LLIPKPLNPA LWFSHSMFMG FYLLSFLLER KPCTICALVF LAALFLICYS
CWGNCFLYHC SDSPLPESAH DPGVVGT