BLCAP_DIDVI
ID BLCAP_DIDVI Reviewed; 87 AA.
AC Q4G2S9;
DT 10-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT 30-AUG-2005, sequence version 1.
DT 25-MAY-2022, entry version 30.
DE RecName: Full=Bladder cancer-associated protein;
GN Name=BLCAP;
OS Didelphis virginiana (North American opossum) (Didelphis marsupialis
OS virginiana).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Metatheria; Didelphimorphia; Didelphidae; Didelphis.
OX NCBI_TaxID=9267;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX PubMed=15901842; DOI=10.1093/molbev/msi165;
RA Evans H.K., Weidman J.R., Cowley D.O., Jirtle R.L.;
RT "Comparative phylogenetic analysis of blcap/nnat reveals eutherian-specific
RT imprinted gene.";
RL Mol. Biol. Evol. 22:1740-1748(2005).
CC -!- FUNCTION: May regulate cell proliferation and coordinate apoptosis and
CC cell cycle progression via a novel mechanism independent of both
CC p53/TP53 and nuclear factor kappa B (NF-kappaB). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the BLCAP family. {ECO:0000305}.
CC ---------------------------------------------------------------------------
CC Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC ---------------------------------------------------------------------------
DR EMBL; AY821914; AAW73084.1; -; Genomic_DNA.
DR AlphaFoldDB; Q4G2S9; -.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR InterPro; IPR009598; BC10.
DR PANTHER; PTHR13259; PTHR13259; 1.
DR SMART; SM01396; BC10; 1.
PE 3: Inferred from homology;
KW Apoptosis; Cell cycle; Membrane; Transmembrane; Transmembrane helix.
FT CHAIN 1..87
FT /note="Bladder cancer-associated protein"
FT /id="PRO_0000295132"
FT TRANSMEM 19..39
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 43..63
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 87 AA; 9985 MW; BE340C116E134684 CRC64;
MYCLQWLLPV LLIPKPLNPA LWFSHSMFMG FYLLSFLLER KPCTICALVF LAALFLICYS
CWGNCFLYHC TGSHLPESAH DPRIVGT