BLCAP_FELCA
ID BLCAP_FELCA Reviewed; 87 AA.
AC P62953; O60629; Q9D3B5;
DT 31-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT 31-AUG-2004, sequence version 1.
DT 03-AUG-2022, entry version 71.
DE RecName: Full=Bladder cancer-associated protein;
DE AltName: Full=Bladder cancer 10 kDa protein;
DE Short=Bc10;
GN Name=BLCAP; Synonyms=BC10;
OS Felis catus (Cat) (Felis silvestris catus).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Felinae; Felis.
OX NCBI_TaxID=9685;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=Fca295; TISSUE=Testis;
RA Hahn Y., Murphy W.J., Chung J.H.;
RT "Identification of feline ortholog of human BLCAP (BC10).";
RL Submitted (MAY-2000) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May regulate cell proliferation and coordinate apoptosis and
CC cell cycle progression via a novel mechanism independent of both
CC p53/TP53 and nuclear factor kappa B (NF-kappaB). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the BLCAP family. {ECO:0000305}.
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DR EMBL; AB043791; BAA96306.1; -; mRNA.
DR RefSeq; NP_001009852.1; NM_001009852.1.
DR RefSeq; XP_019681730.1; XM_019826171.1.
DR AlphaFoldDB; P62953; -.
DR STRING; 9685.ENSFCAP00000017162; -.
DR Ensembl; ENSFCAT00000014322; ENSFCAP00000017162; ENSFCAG00000014318.
DR GeneID; 493843; -.
DR KEGG; fca:493843; -.
DR CTD; 10904; -.
DR VGNC; VGNC:60120; BLCAP.
DR eggNOG; KOG4489; Eukaryota.
DR GeneTree; ENSGT00390000014105; -.
DR HOGENOM; CLU_181908_0_0_1; -.
DR InParanoid; P62953; -.
DR OMA; MERRPCY; -.
DR Proteomes; UP000011712; Chromosome A3.
DR Bgee; ENSFCAG00000014318; Expressed in prefrontal cortex and 10 other tissues.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0030262; P:apoptotic nuclear changes; IEA:Ensembl.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR InterPro; IPR009598; BC10.
DR PANTHER; PTHR13259; PTHR13259; 1.
DR SMART; SM01396; BC10; 1.
PE 3: Inferred from homology;
KW Apoptosis; Cell cycle; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..87
FT /note="Bladder cancer-associated protein"
FT /id="PRO_0000064849"
FT TRANSMEM 19..39
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 43..63
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 87 AA; 9876 MW; 06A45C03E27D3E87 CRC64;
MYCLQWLLPV LLIPKPLNPA LWFSHSMFMG FYLLSFLLER KPCTICALVF LAALFLICYS
CWGNCFLYHC SDSPLPESAH DPGVVGT