BLCAP_MACFA
ID BLCAP_MACFA Reviewed; 87 AA.
AC Q4R504;
DT 10-JUL-2007, integrated into UniProtKB/Swiss-Prot.
DT 19-JUL-2005, sequence version 1.
DT 25-MAY-2022, entry version 38.
DE RecName: Full=Bladder cancer-associated protein;
GN Name=BLCAP; ORFNames=QnpA-11526;
OS Macaca fascicularis (Crab-eating macaque) (Cynomolgus monkey).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini;
OC Cercopithecidae; Cercopithecinae; Macaca.
OX NCBI_TaxID=9541;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Parietal cortex;
RG International consortium for macaque cDNA sequencing and analysis;
RT "DNA sequences of macaque genes expressed in brain or testis and its
RT evolutionary implications.";
RL Submitted (JUN-2005) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: May regulate cell proliferation and coordinate apoptosis and
CC cell cycle progression via a novel mechanism independent of both
CC p53/TP53 and NF-kappa-B. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the BLCAP family. {ECO:0000305}.
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DR EMBL; AB169740; BAE01821.1; -; mRNA.
DR AlphaFoldDB; Q4R504; -.
DR STRING; 9541.XP_005569024.1; -.
DR eggNOG; KOG4489; Eukaryota.
DR Proteomes; UP000233100; Unplaced.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0006915; P:apoptotic process; IEA:UniProtKB-KW.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR InterPro; IPR009598; BC10.
DR PANTHER; PTHR13259; PTHR13259; 1.
DR SMART; SM01396; BC10; 1.
PE 3: Inferred from homology;
KW Apoptosis; Cell cycle; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..87
FT /note="Bladder cancer-associated protein"
FT /id="PRO_0000295133"
FT TRANSMEM 19..39
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 43..63
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 87 AA; 9903 MW; 2BA45C03F6FBE5FE CRC64;
MYCLQWLLPV LLIPKPLNPA LWFSHSMFMG FYLLNFLLER KPCTICALVF LAALFLICYS
CWGNCFLYHC SDSPLPESAH DPGVVGT