BLCAP_RAT
ID BLCAP_RAT Reviewed; 87 AA.
AC P62950; O60629; Q9D3B5;
DT 31-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT 31-AUG-2004, sequence version 1.
DT 03-AUG-2022, entry version 90.
DE RecName: Full=Bladder cancer-associated protein;
DE AltName: Full=Bladder cancer 10 kDa protein;
DE Short=Bc10;
GN Name=Blcap;
OS Rattus norvegicus (Rat).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae;
OC Murinae; Rattus.
OX NCBI_TaxID=10116;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RA Hahn Y.;
RL Submitted (SEP-2001) to the EMBL/GenBank/DDBJ databases.
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC TISSUE=Brain;
RX PubMed=15489334; DOI=10.1101/gr.2596504;
RG The MGC Project Team;
RT "The status, quality, and expansion of the NIH full-length cDNA project:
RT the Mammalian Gene Collection (MGC).";
RL Genome Res. 14:2121-2127(2004).
CC -!- FUNCTION: May regulate cell proliferation and coordinate apoptosis and
CC cell cycle progression via a novel mechanism independent of both
CC p53/TP53 and NF-kappa-B. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the BLCAP family. {ECO:0000305}.
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DR EMBL; AB071598; BAB68312.1; -; mRNA.
DR EMBL; BC087661; AAH87661.1; -; mRNA.
DR RefSeq; NP_598266.1; NM_133582.3.
DR AlphaFoldDB; P62950; -.
DR STRING; 10116.ENSRNOP00000031525; -.
DR PaxDb; P62950; -.
DR Ensembl; ENSRNOT00000033525; ENSRNOP00000031525; ENSRNOG00000024437.
DR GeneID; 171113; -.
DR KEGG; rno:171113; -.
DR UCSC; RGD:621666; rat.
DR CTD; 10904; -.
DR RGD; 621666; Blcap.
DR eggNOG; KOG4489; Eukaryota.
DR GeneTree; ENSGT00390000014105; -.
DR HOGENOM; CLU_181908_0_0_1; -.
DR InParanoid; P62950; -.
DR OMA; MERRPCY; -.
DR OrthoDB; 1521316at2759; -.
DR PhylomeDB; P62950; -.
DR TreeFam; TF313306; -.
DR PRO; PR:P62950; -.
DR Proteomes; UP000002494; Chromosome 3.
DR Bgee; ENSRNOG00000024437; Expressed in frontal cortex and 20 other tissues.
DR Genevisible; P62950; RN.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0030262; P:apoptotic nuclear changes; ISO:RGD.
DR GO; GO:0007049; P:cell cycle; IEA:UniProtKB-KW.
DR InterPro; IPR009598; BC10.
DR PANTHER; PTHR13259; PTHR13259; 1.
DR SMART; SM01396; BC10; 1.
PE 3: Inferred from homology;
KW Apoptosis; Cell cycle; Membrane; Reference proteome; Transmembrane;
KW Transmembrane helix.
FT CHAIN 1..87
FT /note="Bladder cancer-associated protein"
FT /id="PRO_0000064853"
FT TRANSMEM 19..39
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 43..63
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 87 AA; 9876 MW; 06A45C03E27D3E87 CRC64;
MYCLQWLLPV LLIPKPLNPA LWFSHSMFMG FYLLSFLLER KPCTICALVF LAALFLICYS
CWGNCFLYHC SDSPLPESAH DPGVVGT