ID   BLCI_BACIU              Reviewed;          47 AA.
AC   P82243;
DT   09-NOV-2004, integrated into UniProtKB/Swiss-Prot.
DT   25-OCT-2004, sequence version 1.
DT   25-MAY-2022, entry version 42.
DE   RecName: Full=Antimicrobial peptide LCI;
OS   Bacillus subtilis.
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=1423;
RN   [1] {ECO:0000305}
RP   PROTEIN SEQUENCE, AND SUBCELLULAR LOCATION.
RC   STRAIN=A014;
RA   Xu Q.;
RL   Submitted (DEC-1999) to UniProtKB.
RN   [2] {ECO:0000305}
RP   PROTEIN SEQUENCE OF 1-27, FUNCTION, AND STABILITY.
RC   STRAIN=A014 {ECO:0000269|Ref.2};
RA   Liu J.-Y., Pan N.-S., Chen Z.-L.;
RT   "Characterization of an anti-rice bacterial blight polypeptide LCI.";
RL   Rice Genet. Newsl. 7:151-154(1990).
CC   -!- FUNCTION: Has antibacterial activity against X.oryzae pv oryzae and
CC       R.solanacearum, but not E.coli or P.carotovorum subsp carotovorum. May
CC       bind DNA or mRNA. {ECO:0000269|Ref.2}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000269|Ref.1}.
CC   -!- MISCELLANEOUS: Heat stable. Resistant to proteolysis by tryspin and
CC       pepsin, but susceptible to pronase E and proteinase K.
CC       {ECO:0000269|Ref.2}.
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DR   PDB; 2B9K; NMR; -; A=1-47.
DR   PDBsum; 2B9K; -.
DR   AlphaFoldDB; P82243; -.
DR   SMR; P82243; -.
DR   EvolutionaryTrace; P82243; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0042742; P:defense response to bacterium; IEA:UniProtKB-KW.
DR   InterPro; IPR020976; Antimicrobial_lci.
DR   Pfam; PF12197; lci; 1.
PE   1: Evidence at protein level;
KW   3D-structure; Antibiotic; Antimicrobial; Direct protein sequencing;
KW   Secreted.
FT   CHAIN           1..47
FT                   /note="Antimicrobial peptide LCI"
FT                   /id="PRO_0000064937"
FT   STRAND          3..7
FT                   /evidence="ECO:0007829|PDB:2B9K"
FT   STRAND          15..18
FT                   /evidence="ECO:0007829|PDB:2B9K"
FT   STRAND          21..30
FT                   /evidence="ECO:0007829|PDB:2B9K"
FT   TURN            32..34
FT                   /evidence="ECO:0007829|PDB:2B9K"
FT   STRAND          35..43
FT                   /evidence="ECO:0007829|PDB:2B9K"
SQ   SEQUENCE   47 AA;  5464 MW;  B41DADC98F76432E CRC64;
     AIKLVQSPNG NFAASFVLDG TKWIFKSKYY DSSKGYWVGI YEVWDRK