ID   BLH7_ARATH              Reviewed;         482 AA.
AC   Q9SIW1; Q93ZM1;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-MAY-2000, sequence version 1.
DT   25-MAY-2022, entry version 135.
DE   RecName: Full=BEL1-like homeodomain protein 7;
DE            Short=BEL1-like protein 7;
GN   Name=BLH7; OrderedLocusNames=At2g16400; ORFNames=F16F14.10;
OS   Arabidopsis thaliana (Mouse-ear cress).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC   rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX   NCBI_TaxID=3702;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=10617197; DOI=10.1038/45471;
RA   Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA   Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA   Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA   Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA   Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA   Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA   Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT   "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL   Nature 402:761-768(1999).
RN   [2]
RP   GENOME REANNOTATION.
RC   STRAIN=cv. Columbia;
RX   PubMed=27862469; DOI=10.1111/tpj.13415;
RA   Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA   Town C.D.;
RT   "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT   genome.";
RL   Plant J. 89:789-804(2017).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=cv. Columbia;
RX   PubMed=14593172; DOI=10.1126/science.1088305;
RA   Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA   Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA   Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA   Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA   Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA   Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA   Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA   Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA   Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA   Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA   Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA   Ecker J.R.;
RT   "Empirical analysis of transcriptional activity in the Arabidopsis
RT   genome.";
RL   Science 302:842-846(2003).
RN   [4]
RP   GENE FAMILY ORGANIZATION.
RX   PubMed=15120075; DOI=10.1016/j.cub.2004.04.032;
RA   Smith H.M.S., Campbell B.C.C., Hake S.;
RT   "Competence to respond to floral inductive signals requires the homeobox
RT   genes PENNYWISE and POUND-FOOLISH.";
RL   Curr. Biol. 14:812-817(2004).
CC   -!- SUBUNIT: May form heterodimeric complexes with TALE/KNOX proteins.
CC       {ECO:0000250}.
CC   -!- INTERACTION:
CC       Q9SIW1; P46639: KNAT1; NbExp=5; IntAct=EBI-1153967, EBI-530486;
CC       Q9SIW1; P48000: KNAT3; NbExp=3; IntAct=EBI-1153967, EBI-1153908;
CC       Q9SIW1; Q84JS6: KNAT6; NbExp=3; IntAct=EBI-1153967, EBI-530499;
CC   -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC   -!- DOMAIN: The SR/KY and BELL domains are responsive for the interaction
CC       between the TALE/BELL proteins and the TALE/KNOX proteins.
CC   -!- SIMILARITY: Belongs to the TALE/BELL homeobox family. {ECO:0000305}.
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DR   EMBL; AC007047; AAD22299.1; -; Genomic_DNA.
DR   EMBL; CP002685; AEC06493.1; -; Genomic_DNA.
DR   EMBL; AY056796; AAL10487.1; -; mRNA.
DR   EMBL; BT000609; AAN18176.1; -; mRNA.
DR   PIR; H84539; H84539.
DR   RefSeq; NP_179233.1; NM_127194.4.
DR   AlphaFoldDB; Q9SIW1; -.
DR   SMR; Q9SIW1; -.
DR   BioGRID; 1495; 11.
DR   IntAct; Q9SIW1; 11.
DR   STRING; 3702.AT2G16400.1; -.
DR   PaxDb; Q9SIW1; -.
DR   PRIDE; Q9SIW1; -.
DR   ProteomicsDB; 240356; -.
DR   EnsemblPlants; AT2G16400.1; AT2G16400.1; AT2G16400.
DR   GeneID; 816137; -.
DR   Gramene; AT2G16400.1; AT2G16400.1; AT2G16400.
DR   KEGG; ath:AT2G16400; -.
DR   Araport; AT2G16400; -.
DR   TAIR; locus:2042609; AT2G16400.
DR   eggNOG; KOG0773; Eukaryota.
DR   HOGENOM; CLU_011058_6_0_1; -.
DR   InParanoid; Q9SIW1; -.
DR   OMA; QMVEIQD; -.
DR   OrthoDB; 311531at2759; -.
DR   PhylomeDB; Q9SIW1; -.
DR   PRO; PR:Q9SIW1; -.
DR   Proteomes; UP000006548; Chromosome 2.
DR   ExpressionAtlas; Q9SIW1; baseline and differential.
DR   Genevisible; Q9SIW1; AT.
DR   GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR   GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR   GO; GO:0000981; F:DNA-binding transcription factor activity, RNA polymerase II-specific; IBA:GO_Central.
DR   GO; GO:0000978; F:RNA polymerase II cis-regulatory region sequence-specific DNA binding; IBA:GO_Central.
DR   GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR   GO; GO:0006357; P:regulation of transcription by RNA polymerase II; IBA:GO_Central.
DR   CDD; cd00086; homeodomain; 1.
DR   InterPro; IPR009057; Homeobox-like_sf.
DR   InterPro; IPR001356; Homeobox_dom.
DR   InterPro; IPR008422; Homeobox_KN_domain.
DR   InterPro; IPR006563; POX_dom.
DR   Pfam; PF05920; Homeobox_KN; 1.
DR   Pfam; PF07526; POX; 1.
DR   SMART; SM00389; HOX; 1.
DR   SMART; SM00574; POX; 1.
DR   SUPFAM; SSF46689; SSF46689; 1.
DR   PROSITE; PS00027; HOMEOBOX_1; 1.
DR   PROSITE; PS50071; HOMEOBOX_2; 1.
PE   1: Evidence at protein level;
KW   DNA-binding; Homeobox; Nucleus; Reference proteome; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..482
FT                   /note="BEL1-like homeodomain protein 7"
FT                   /id="PRO_0000315463"
FT   DNA_BIND        285..347
FT                   /note="Homeobox"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00108"
FT   REGION          118..134
FT                   /note="SR/KY domain"
FT   REGION          167..238
FT                   /note="BELL domain"
FT   REGION          358..401
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        361..401
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   CONFLICT        453
FT                   /note="T -> I (in Ref. 3; AAL10487/AAN18176)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   482 AA;  54244 MW;  3E289F5802FDDAE1 CRC64;
     MATYYKTGSS EIYSRPEFVP GNAMNYTNSF TETFPRDSTN NVSPSKEIQV LSSLGGVSQM
     VEIQDSGSWR DQEDNDRNRF PVMRRLGLSS QIETSRGNNN NEYATQVVSG FTRTIHNSKY
     LKAAQELLDE TVNVKKALKQ FQPEGDKINE VKEKNLQTNT AEIPQAERQE LQSKLSKLLS
     ILDEVDRNYK QYYHQMQIVV SSFDVIAGCG AAKPYTALAL QTISRHFRCL RDAISGQILV
     IRKSLGGEQD GSDGRGVGIS RLRNVDQQVR QQRALQRLGV MQPHTWRPQR GLPDSSVLVL
     RAWLFEHFLH PYPKDSDKIM LARQTGLSRG QVSNWFINAR VRLWKPMVEE MYKEEFTDAL
     QENDPNQSSE NTPEITEIQE LQTESSSNNG HVPGVASSSM RQNTVAHGGD RFMMVTDMTR
     NGNGGMSLTL GIQNSDARGD VPMSGGIDNY KNTISGTDLQ YLNSRNHQHQ IGSSQLLHDF
     VA