ID   SYLV_PROSY              Reviewed;          22 AA.
AC   P0C1R2;
DT   25-JUL-2006, integrated into UniProtKB/Swiss-Prot.
DT   25-JUL-2006, sequence version 1.
DT   25-MAY-2022, entry version 18.
DE   RecName: Full=Sylverin;
OS   Protonectarina sylveirae (Brazilian wasp).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Hymenoptera; Apocrita; Aculeata; Vespoidea;
OC   Vespidae; Polistinae; Epiponini; Protonectarina.
OX   NCBI_TaxID=91438;
RN   [1]
RP   PROTEIN SEQUENCE, AND SYNTHESIS.
RC   TISSUE=Venom;
RX   PubMed=7513243; DOI=10.1002/nt.2620010503;
RA   Dohtsu K., Okumura K., Hagiwara K., Palma M.S., Nakajima T.;
RT   "Isolation and sequence analysis of peptides from the venom of
RT   Protonectarina sylveirae (Hymenoptera-Vespidae).";
RL   Nat. Toxins 1:271-276(1993).
CC   -!- FUNCTION: This non-hemolytic peptide shows potent histamine releasing
CC       activities on rat peritoneal mast cells.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- TISSUE SPECIFICITY: Expressed by the venom gland.
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DR   AlphaFoldDB; P0C1R2; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0043303; P:mast cell degranulation; IEA:UniProtKB-KW.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Mast cell degranulation; Secreted.
FT   PEPTIDE         1..22
FT                   /note="Sylverin"
FT                   /id="PRO_0000247271"
SQ   SEQUENCE   22 AA;  2471 MW;  9E2DA4879FB1B05D CRC64;
     SIKEKICKII EAKIGKKPPF CP