BLP1_CANAL
ID BLP1_CANAL Reviewed; 77 AA.
AC P0CT51; A0A1D8PFI4;
DT 07-JAN-2015, integrated into UniProtKB/Swiss-Prot.
DT 07-JAN-2015, sequence version 1.
DT 25-MAY-2022, entry version 11.
DE RecName: Full=Blood-induced peptide 1 {ECO:0000303|PubMed:23948566};
GN Name=BLP1 {ECO:0000303|PubMed:23948566};
GN OrderedLocusNames=CAALFM_C112850WA; ORFNames=CaO19.4914.1, orf19.4914.1;
OS Candida albicans (strain SC5314 / ATCC MYA-2876) (Yeast).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Candida/Lodderomyces clade; Candida.
OX NCBI_TaxID=237561;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SC5314 / ATCC MYA-2876;
RX PubMed=15123810; DOI=10.1073/pnas.0401648101;
RA Jones T., Federspiel N.A., Chibana H., Dungan J., Kalman S., Magee B.B.,
RA Newport G., Thorstenson Y.R., Agabian N., Magee P.T., Davis R.W.,
RA Scherer S.;
RT "The diploid genome sequence of Candida albicans.";
RL Proc. Natl. Acad. Sci. U.S.A. 101:7329-7334(2004).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=SC5314 / ATCC MYA-2876;
RX PubMed=17419877; DOI=10.1186/gb-2007-8-4-r52;
RA van het Hoog M., Rast T.J., Martchenko M., Grindle S., Dignard D.,
RA Hogues H., Cuomo C., Berriman M., Scherer S., Magee B.B., Whiteway M.,
RA Chibana H., Nantel A., Magee P.T.;
RT "Assembly of the Candida albicans genome into sixteen supercontigs aligned
RT on the eight chromosomes.";
RL Genome Biol. 8:RESEARCH52.1-RESEARCH52.12(2007).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA], AND GENOME REANNOTATION.
RC STRAIN=SC5314 / ATCC MYA-2876;
RX PubMed=24025428; DOI=10.1186/gb-2013-14-9-r97;
RA Muzzey D., Schwartz K., Weissman J.S., Sherlock G.;
RT "Assembly of a phased diploid Candida albicans genome facilitates allele-
RT specific measurements and provides a simple model for repeat and indel
RT structure.";
RL Genome Biol. 14:RESEARCH97.1-RESEARCH97.14(2013).
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=SC5314 / ATCC MYA-2876;
RX PubMed=19465905; DOI=10.1038/nature08064;
RA Butler G., Rasmussen M.D., Lin M.F., Santos M.A.S., Sakthikumar S.,
RA Munro C.A., Rheinbay E., Grabherr M., Forche A., Reedy J.L., Agrafioti I.,
RA Arnaud M.B., Bates S., Brown A.J.P., Brunke S., Costanzo M.C.,
RA Fitzpatrick D.A., de Groot P.W.J., Harris D., Hoyer L.L., Hube B.,
RA Klis F.M., Kodira C., Lennard N., Logue M.E., Martin R., Neiman A.M.,
RA Nikolaou E., Quail M.A., Quinn J., Santos M.C., Schmitzberger F.F.,
RA Sherlock G., Shah P., Silverstein K.A.T., Skrzypek M.S., Soll D.,
RA Staggs R., Stansfield I., Stumpf M.P.H., Sudbery P.E., Srikantha T.,
RA Zeng Q., Berman J., Berriman M., Heitman J., Gow N.A.R., Lorenz M.C.,
RA Birren B.W., Kellis M., Cuomo C.A.;
RT "Evolution of pathogenicity and sexual reproduction in eight Candida
RT genomes.";
RL Nature 459:657-662(2009).
RN [5]
RP IDENTIFICATION BY MASS SPECTROMETRY, INDUCTION, AND FUNCTION.
RC STRAIN=SC5314 / ATCC MYA-2876;
RX PubMed=23948566; DOI=10.1016/j.jprot.2013.07.031;
RA Aoki W., Tatsukami Y., Kitahara N., Matsui K., Morisaka H., Kuroda K.,
RA Ueda M.;
RT "Elucidation of potentially virulent factors of Candida albicans during
RT serum adaptation by using quantitative time-course proteomics.";
RL J. Proteomics 91:417-429(2013).
CC -!- FUNCTION: Plays an important role in survival in host blood through
CC increasing tolerance to stresses such as heat, salt, or cycloheximide,
CC which is essential for virulence. {ECO:0000269|PubMed:23948566}.
CC -!- INDUCTION: Highly up-regulated by fetal bovine serum.
CC {ECO:0000269|PubMed:23948566}.
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DR EMBL; CP017623; AOW26900.1; -; Genomic_DNA.
DR RefSeq; XP_019330715.1; XM_019475170.1.
DR AlphaFoldDB; P0CT51; -.
DR SMR; P0CT51; -.
DR GeneID; 30515065; -.
DR KEGG; cal:CAALFM_C112850WA; -.
DR CGD; CAL0000190643; BLP1.
DR VEuPathDB; FungiDB:C1_12850W_A; -.
DR Proteomes; UP000000559; Chromosome 1.
PE 1: Evidence at protein level;
KW Coiled coil; Reference proteome; Stress response.
FT CHAIN 1..77
FT /note="Blood-induced peptide 1"
FT /id="PRO_0000431532"
FT COILED 38..71
FT /evidence="ECO:0000255"
SQ SEQUENCE 77 AA; 9031 MW; 6454015CC66A6788 CRC64;
MDFKRKLSEV DADAAEDVKM DMGATIIPQR ERATSVIEDF LHQENSELKK SLKNLEMENE
KLKNILKTDY NVNYIRK