ID   BLR31_BRELC             Reviewed;         126 AA.
AC   A0A286SC82;
DT   05-JUN-2019, integrated into UniProtKB/Swiss-Prot.
DT   22-NOV-2017, sequence version 1.
DT   25-MAY-2022, entry version 11.
DE   RecName: Full=RxLR effector protein BLR31 {ECO:0000303|PubMed:28833168};
DE   Flags: Precursor;
GN   Name=BLR31 {ECO:0000303|PubMed:28833168};
OS   Bremia lactucae (Lettuce downy mildew).
OC   Eukaryota; Sar; Stramenopiles; Oomycota; Peronosporales; Peronosporaceae;
OC   Bremia.
OX   NCBI_TaxID=4779;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA], DOMAIN, INDUCTION, AND FUNCTION.
RC   STRAIN=Race Bl:24;
RX   PubMed=28833168; DOI=10.1111/nph.14741;
RA   Giesbers A.K.J., Pelgrom A.J.E., Visser R.G.F., Niks R.E.,
RA   Van den Ackerveken G., Jeuken M.J.W.;
RT   "Effector-mediated discovery of a novel resistance gene against Bremia
RT   lactucae in a nonhost lettuce species.";
RL   New Phytol. 216:915-926(2017).
CC   -!- FUNCTION: Secreted effector that triggers a hypersensitive response
CC       (HR) in 3 Lactuca saligna accessions (CGN05947, CGN05310, CGN05304).
CC       {ECO:0000269|PubMed:28833168}.
CC   -!- SUBCELLULAR LOCATION: Secreted {ECO:0000305|PubMed:28833168}. Host cell
CC       {ECO:0000305|PubMed:28833168}.
CC   -!- INDUCTION: Expressed during host plant infection.
CC       {ECO:0000269|PubMed:28833168}.
CC   -!- DOMAIN: The RxLR-dEER motif acts to carry the protein into the host
CC       cell cytoplasm through binding to cell surface phosphatidylinositol-3-
CC       phosphate. {ECO:0000305|PubMed:28833168}.
CC   -!- SIMILARITY: Belongs to the RxLR effector family. {ECO:0000305}.
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DR   EMBL; KY940276; ASZ00240.1; -; mRNA.
DR   AlphaFoldDB; A0A286SC82; -.
DR   VEuPathDB; FungiDB:CCR75_008983; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0043657; C:host cell; IEA:UniProtKB-SubCell.
PE   2: Evidence at transcript level;
KW   Secreted; Signal.
FT   SIGNAL          1..22
FT                   /evidence="ECO:0000255"
FT   CHAIN           23..126
FT                   /note="RxLR effector protein BLR31"
FT                   /evidence="ECO:0000255"
FT                   /id="PRO_5012809571"
FT   MOTIF           44..58
FT                   /note="RxLR-dEER"
FT                   /evidence="ECO:0000305|PubMed:28833168"
SQ   SEQUENCE   126 AA;  14315 MW;  7C6BAE4A86EF6073 CRC64;
     MLLSRAISVL ALLACIRCGV HAQNTEQNLK TQLTTDSAMI TSQRLLRTSV DFKDSEERWP
     TESSRIRSAI KDYFREFPEK VSIAMAIRQI DAHGVRHVEK VLSQYKFPAA DQGNIRLAII
     HHKAPK