ID   BLS_STRMO               Reviewed;         136 AA.
AC   P19997;
DT   01-FEB-1991, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1991, sequence version 1.
DT   25-MAY-2022, entry version 67.
DE   RecName: Full=Blasticidin-S acetyltransferase;
DE            EC=2.3.1.-;
GN   Name=bls;
OS   Streptomyces morookaense (Streptoverticillium morookaense).
OC   Bacteria; Actinobacteria; Streptomycetales; Streptomycetaceae;
OC   Streptomyces.
OX   NCBI_TaxID=1970;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2311933; DOI=10.1016/0378-1119(90)90125-b;
RA   Perez-Gonzalez J.A., Ruiz D., Esteban J.A., Jimenez A.;
RT   "Cloning and characterization of the gene encoding a blasticidin S
RT   acetyltransferase from Streptoverticillum sp.";
RL   Gene 86:129-134(1990).
CC   -!- FUNCTION: Confers resistance to blasticidin S antibiotic.
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DR   EMBL; M34537; AAA26840.1; -; Genomic_DNA.
DR   PIR; JQ0421; JQ0421.
DR   AlphaFoldDB; P19997; -.
DR   SMR; P19997; -.
DR   GO; GO:0008080; F:N-acetyltransferase activity; IEA:InterPro.
DR   GO; GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
DR   InterPro; IPR016181; Acyl_CoA_acyltransferase.
DR   InterPro; IPR000182; GNAT_dom.
DR   Pfam; PF00583; Acetyltransf_1; 1.
DR   SUPFAM; SSF55729; SSF55729; 1.
DR   PROSITE; PS51186; GNAT; 1.
PE   4: Predicted;
KW   Acyltransferase; Antibiotic resistance; Transferase.
FT   CHAIN           1..136
FT                   /note="Blasticidin-S acetyltransferase"
FT                   /id="PRO_0000064944"
FT   DOMAIN          1..136
FT                   /note="N-acetyltransferase"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00532"
SQ   SEQUENCE   136 AA;  15073 MW;  38201A66614900AC CRC64;
     MLSLPRLQTV NDERSPALRA LRRTPVMEAR PLEVYATYAC GERGELAGGL VGHVQWQWLH
     VDLLWVDAGA RGAGLGSRLI ARAEARAREE FGCIGSQVET WDFQAPGFYQ RVGYRLAASI
     PDYPPGITSH LLVKEL