ID   SYME_SALCH              Reviewed;         110 AA.
AC   Q57G77;
DT   21-AUG-2007, integrated into UniProtKB/Swiss-Prot.
DT   10-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 70.
DE   RecName: Full=Endoribonuclease SymE {ECO:0000255|HAMAP-Rule:MF_01193};
DE            EC=3.1.-.- {ECO:0000255|HAMAP-Rule:MF_01193};
GN   Name=symE {ECO:0000255|HAMAP-Rule:MF_01193}; OrderedLocusNames=SCH_4379;
OS   Salmonella choleraesuis (strain SC-B67).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Salmonella.
OX   NCBI_TaxID=321314;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SC-B67;
RX   PubMed=15781495; DOI=10.1093/nar/gki297;
RA   Chiu C.-H., Tang P., Chu C., Hu S., Bao Q., Yu J., Chou Y.-Y., Wang H.-S.,
RA   Lee Y.-S.;
RT   "The genome sequence of Salmonella enterica serovar Choleraesuis, a highly
RT   invasive and resistant zoonotic pathogen.";
RL   Nucleic Acids Res. 33:1690-1698(2005).
CC   -!- FUNCTION: Involved in the degradation and recycling of damaged RNA. It
CC       is itself a target for degradation by the ATP-dependent protease Lon.
CC       {ECO:0000255|HAMAP-Rule:MF_01193}.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm {ECO:0000255|HAMAP-Rule:MF_01193}.
CC   -!- SIMILARITY: Belongs to the SymE family. {ECO:0000255|HAMAP-
CC       Rule:MF_01193}.
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DR   EMBL; AE017220; AAX68285.1; -; Genomic_DNA.
DR   RefSeq; WP_001541462.1; NC_006905.1.
DR   AlphaFoldDB; Q57G77; -.
DR   EnsemblBacteria; AAX68285; AAX68285; SCH_4379.
DR   KEGG; sec:SCH_4379; -.
DR   HOGENOM; CLU_151239_0_0_6; -.
DR   OMA; MRQHTRT; -.
DR   Proteomes; UP000000538; Chromosome.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0004521; F:endoribonuclease activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0003723; F:RNA binding; IEA:UniProtKB-KW.
DR   HAMAP; MF_01193; Endoribonucl_SymE; 1.
DR   InterPro; IPR007159; SpoVT-AbrB_dom.
DR   InterPro; IPR014944; Toxin_SymE-like.
DR   InterPro; IPR020883; TypeI_TA_SymE.
DR   Pfam; PF08845; SymE_toxin; 1.
DR   PROSITE; PS51740; SPOVT_ABRB; 1.
PE   3: Inferred from homology;
KW   Cytoplasm; DNA-binding; Endonuclease; Hydrolase; Nuclease; RNA-binding.
FT   CHAIN           1..110
FT                   /note="Endoribonuclease SymE"
FT                   /id="PRO_0000297823"
FT   DOMAIN          29..74
FT                   /note="SpoVT-AbrB"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU01076"
SQ   SEQUENCE   110 AA;  12184 MW;  45E80F28E8F95E67 CRC64;
     MTTPHSIAES TDPEVFPANN RHLTVSYASS YPEYTRIPAI TLKGQWLEDA GFTTGTQVDV
     RVMNGCIVLT AQQPQPEESE LMQSLRQVSK LSARKQKQVQ AFIDVMAGSK